GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for kdgA (2-keto-3-deoxygluconate-6-phosphate aldolase EC:4.1.2.14) in D-glucosamine (chitosamine) catabolism

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Definition of kdgA

Fetched 9 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 8 of these sequences

Found 2 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 288-308 amino acids (not heteromeric)

KDGA_SULAC / Q4JC35 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase; EC 4.1.2.55 from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Q4JC35 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6 phosphogalactonate aldolase (EC 4.1.2.55) from Sulfolobus acidocaldarius
PFams: DHDPS
288 amino acids: PaperBLAST, CDD, Compare to cluster

KDGA_SACS2 / Q97U28 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase; EC 4.1.2.55 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
Q97U28 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6 phosphogalactonate aldolase (EC 4.1.2.55) from Saccharolobus solfataricus
PFams: DHDPS
308 amino acids: PaperBLAST, CDD, Compare to cluster

KDGA_SULTO / F9VPG1 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase; EC 4.1.2.55 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii)
F9VPG1 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6 phosphogalactonate aldolase (EC 4.1.2.55) from Sulfurisphaera tokodaii
PFams: DHDPS
290 amino acids: PaperBLAST, CDD, Compare to cluster

KDGA_SACSO / O54288 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase; EC 4.1.2.55 from Saccharolobus solfataricus (Sulfolobus solfataricus)
O54288 2-dehydro-3-deoxy-phosphogluconate aldolase (EC 4.1.2.14); 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6 phosphogalactonate aldolase (EC 4.1.2.55) from Saccharolobus solfataricus
O54288 KDG-aldolase subunit (EC 4.1.2.28; EC 4.1.2.18; EC 4.1.2.51) from Saccharolobus solfataricus
PFams: DHDPS
294 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 205-213 amino acids (not heteromeric)

Q9WXS1 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16; EC 4.1.2.55) from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
PFams: Aldolase
205 amino acids: PaperBLAST, CDD, Compare to cluster

b1850 KHG/KDPG aldolase (EC 4.1.2.55; EC 4.1.2.14; EC 4.1.3.42; EC 4.1.1.112) from Escherichia coli K-12 substr. MG1655
ALKH_ECOLI / P0A955 KHG/KDPG aldolase; EC 4.1.3.16; EC 4.1.2.14 from Escherichia coli (strain K12)
P0A955 2-dehydro-3-deoxy-phosphogluconate aldolase (EC 4.1.2.14); 4-Hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16); (4S)-4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.42) from Escherichia coli
P0A955 KHG/KDPG aldolase (EC 4.1.2.55; EC 4.1.3.42; EC 4.1.1.112) from Escherichia coli (strain K12)
RF|NP_416364 KHG/KDPG aldolase; EC 4.1.2.14; EC 4.1.3.16 from Escherichia coli K12
PFams: Aldolase
213 amino acids: PaperBLAST, CDD, Compare to cluster

b4477 2-dehydro-3-deoxy-6-phosphogalactonate aldolase (EC 4.1.2.55; EC 4.1.2.21) from Escherichia coli K-12 substr. MG1655
DGOA_ECOLI / Q6BF16 2-dehydro-3-deoxy-6-phosphogalactonate aldolase; 2-oxo-3-deoxygalactonate 6-phosphate aldolase; 6-phospho-2-dehydro-3-deoxygalactonate aldolase; 6-phospho-2-keto-3-deoxygalactonate aldolase; KDPGal; EC 4.1.2.21 from Escherichia coli (strain K12)
Q6BF16 2-dehydro-3-deoxy-6-phosphogalactonate aldolase (EC 4.1.2.21) from Escherichia coli
Q6BF16 2-dehydro-3-deoxy-6-phosphogalactonate aldolase (EC 4.1.2.55) from Escherichia coli (strain K12)
RF|YP_026238 2-dehydro-3-deoxy-6-phosphogalactonate aldolase from Escherichia coli K12
PFams: Aldolase
205 amino acids: PaperBLAST, CDD, Compare to cluster

P38448 2-dehydro-3-deoxy-D-gluconate-6-phosphate aldolase (EC 4.1.2.55) from Dickeya dadantii (strain 3937)
PFams: Aldolase
213 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/1 heteromeric)

DGAF_SALT1 / D0ZLR2 2-dehydro-3-deoxy-phosphogluconate aldolase; Keto-3-deoxygluconate 6-phosphate aldolase; KDGP aldolase; EC 4.1.2.14 from Salmonella typhimurium (strain 14028s / SGSC 2262)
D0ZLR2 2-dehydro-3-deoxy-phosphogluconate aldolase (EC 4.1.2.55) from Salmonella typhimurium (strain 14028s / SGSC 2262)
PFams: KDGP_aldolase
247 amino acids: PaperBLAST, CDD