Other Characterized Proteins Similar to nagK

GapMind for catabolism of small carbon sources

Other Characterized Proteins Similar to nagK

Finding the characterized proteins for nagK (N-acetylglucosamine kinase) in D-glucosamine (chitosamine) catabolism

Or see clustering for step nagK

Or see all steps for D-glucosamine (chitosamine) catabolism

Or cluster curated proteins matching a keyword

Definition of nagK

Curated proteins or TIGRFams with EC 2.7.1.59
Ignore hits to CH_123431 when looking for 'other' hits (N-acetylglucosamine kinase)
UniProt sequence Q8P6S9: SubName: Full=Glucose kinase {ECO:0000313|EMBL:AAM42158.1};
UniProt sequence Q8P6M4: SubName: Full=Glucose kinase {ECO:0000313|EMBL:AAM42215.1};
Comment: Ignore a putative enzyme from C. albicans, not given this EC number in CharProtDB. PMC2832512 identified two NAG kinases in Xanthomonas campestris, XCC2886 (Q8P6S9) and XCC2943 (Q8P6M4)

Fetched 18 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 5 other characterized sequences. (Found 21 hits including self hits.)

Removing ignored items reduces this to 4 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for nagK.)

Sama_2231 glucokinase (EC 2.7.1.2) from Shewanella amazonensis SB2B
PFams: ROK, Glucokinase
299 amino acids: PaperBLAST, CDD, reanno::SB2B:6938110
42% identical to

b1119 N-acetyl-D-glucosamine kinase (EC 2.7.1.59) from Escherichia coli K-12 substr. MG1655
P75959 N-acetyl-D-glucosamine kinase (EC 2.7.1.59) from Escherichia coli (strain K12)
NAGK_ECOLI / P75959 N-acetyl-D-glucosamine kinase; GlcNAc kinase; EC 2.7.1.59 from Escherichia coli (strain K12)
GB|ABB62126.1 N-acetyl-D-glucosamine kinase; EC 2.7.1.59 from Escherichia coli K12
PFams: ROK, Glucokinase
303 amino acids: PaperBLAST, CDD

b0394 fructokinase (EC 2.7.1.7; EC 2.7.1.4) from Escherichia coli K-12 substr. MG1655
P23917 fructokinase (EC 2.7.1.7; EC 2.7.1.4) from Escherichia coli (strain K12)
MAK_ECOLI / P23917 Fructokinase; D-fructose kinase; Manno(fructo)kinase; EC 2.7.1.4 from Escherichia coli (strain K12)
PFams: ROK, Glucokinase
302 amino acids: PaperBLAST, CDD, SwissProt::P23917
40% identical to

Sama_1405 glucokinase (EC 2.7.1.2) from Shewanella amazonensis SB2B
PFams: ROK, Glucokinase
310 amino acids: PaperBLAST, CDD, reanno::SB2B:6937235
40% identical to

SMc03109 Mannokinase (EC 2.7.1.7) from Sinorhizobium meliloti 1021
PFams: ROK
298 amino acids: PaperBLAST, CDD, reanno::Smeli:SMc03109
40% identical to

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for nagK.)

CH_123431 N-acetylglucosamine kinase from Candida albicans
PFams: Hexokinase_1, Hexokinase_2
493 amino acids: PaperBLAST, CDD, CharProtDB::CH_123431
99% identical to

HXK1_CANAL / Q59RW5 N-acetylglucosamine kinase 1; GlcNAc kinase 1; Hexokinase 1; EC 2.7.1.59; EC 2.7.1.1 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
PFams: Hexokinase_1, Hexokinase_2
493 amino acids: PaperBLAST, CDD