GapMind for catabolism of small carbon sources

 

Other Characterized Proteins Similar to manZ

Finding the characterized proteins for manZ (glucose PTS, enzyme EIID) in D-glucose catabolism

Or see clustering for step manZ

Or see all steps for D-glucose catabolism

Or cluster curated proteins matching a keyword

Definition of manZ

Fetched 6 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 7 other characterized sequences. (Found 13 hits including self hits.)

Removing ignored items reduces this to 5 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for manZ.)

TC 4.A.6.1.16 / Q8Y8W1 Lmo0781 protein, component of Constitutively synthesized sensor, MpoABCD, controlling man operon (see TC# 4.A.6.1.15) expression by interacting with and phosphorylating ManR, the transcriptional regulator of the man operon from Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
PFams: EIID-AGA
Heteromeric, 292 amino acids: PaperBLAST, CDD, TCDB::Q8Y8W1
72% identical to

TC 4.A.6.1.1 / P69805 PTND aka MANZ aka PTSM aka GPTB aka B1819, component of The mannose (glucose, 2-deoxyglucose, glucosamine, N-acetylglucosamine, N-acetylmannosamine, mannosamine and fructose) PTS porter/group translocator, ManXYZ (Rephaeli and Saier 1980; Plumbridge 2015). Catalyzes xylose facilitated diffusion in lactobacilli. The order of D-sugar substrate affinities is: glucose > mannose > 2-deoxyglucose > N-acetylglucosamine > glucosamine > N-acetylmannosamine > mannosamine > fructose from Escherichia coli
PFams: EIID-AGA
Heteromeric, 286 amino acids: PaperBLAST, CDD

PTRD_KLEPN / P37083 PTS system sorbose-specific EIID component; EIID-Sor; Sorbose permease IID component from Klebsiella pneumoniae
TC 4.A.6.1.3 / P37083 PTRD aka SORM, component of Sorbose porter from Klebsiella pneumoniae
PFams: EIID-AGA
Heteromeric, 274 amino acids: PaperBLAST, CDD, SwissProt::P37083
61% identical to

b1819 mannose-specific PTS enzyme IID component (EC 2.7.1.191; EC 2.7.1.199; EC 2.7.1.193) from Escherichia coli K-12 substr. MG1655
PTND_ECOLI / P69805 PTS system mannose-specific EIID component; EII-M-Man; EIID-Man; Mannose permease IID component from Escherichia coli (strain K12)
P69805 mannose-specific PTS enzyme IID component (EC 2.7.1.191; EC 2.7.1.199; EC 2.7.1.193) from Escherichia coli (strain K12)
PFams: EIID-AGA
Heteromeric, 283 amino acids: PaperBLAST, CDD

TC 4.A.6.1.2 / P26382 PTFD aka LEVG, component of Fructose group translocator, LevDEFG from Bacillus subtilis
PFams: EIID-AGA
Heteromeric, 275 amino acids: PaperBLAST, CDD, TCDB::P26382
60% identical to

b1819 mannose-specific PTS enzyme IID component (EC 2.7.1.191; EC 2.7.1.199; EC 2.7.1.193) from Escherichia coli K-12 substr. MG1655
PTND_ECOLI / P69805 PTS system mannose-specific EIID component; EII-M-Man; EIID-Man; Mannose permease IID component from Escherichia coli (strain K12)
P69805 mannose-specific PTS enzyme IID component (EC 2.7.1.191; EC 2.7.1.199; EC 2.7.1.193) from Escherichia coli (strain K12)
PFams: EIID-AGA
Heteromeric, 283 amino acids: PaperBLAST, CDD

PTRD_LACCA / Q9RGG2 PTS system sorbose-specific EIID component; EIID-Sor; Sorbose permease IID component from Lactobacillus casei
Q9RGG2 protein-Npi-phosphohistidine-L-sorbose phosphotransferase (subunit 1/4) (EC 2.7.1.206) from Lactobacillus casei
PFams: EIID-AGA
Heteromeric, 282 amino acids: PaperBLAST, CDD, SwissProt::Q9RGG2
56% identical to

b1819 mannose-specific PTS enzyme IID component (EC 2.7.1.191; EC 2.7.1.199; EC 2.7.1.193) from Escherichia coli K-12 substr. MG1655
PTND_ECOLI / P69805 PTS system mannose-specific EIID component; EII-M-Man; EIID-Man; Mannose permease IID component from Escherichia coli (strain K12)
P69805 mannose-specific PTS enzyme IID component (EC 2.7.1.191; EC 2.7.1.199; EC 2.7.1.193) from Escherichia coli (strain K12)
PFams: EIID-AGA
Heteromeric, 283 amino acids: PaperBLAST, CDD

TC 4.A.6.1.19 / V7RGM6 PTS mannose transporter subunit IID, component of PTS uptake system for glucoselysine and fructoselysine, GfrABCD from Salmonella enterica subsp. enterica serovar Give var. 15 str. CFSAN004343
A0A0F6BB80 fructoselysine/glucoselysine PTS enzyme IID component from Salmonella typhimurium (strain 14028s / SGSC 2262)
PFams: EIID-AGA
Heteromeric, 278 amino acids: PaperBLAST, CDD, TCDB::V7RGM6
40% identical to

b1819 mannose-specific PTS enzyme IID component (EC 2.7.1.191; EC 2.7.1.199; EC 2.7.1.193) from Escherichia coli K-12 substr. MG1655
PTND_ECOLI / P69805 PTS system mannose-specific EIID component; EII-M-Man; EIID-Man; Mannose permease IID component from Escherichia coli (strain K12)
P69805 mannose-specific PTS enzyme IID component (EC 2.7.1.191; EC 2.7.1.199; EC 2.7.1.193) from Escherichia coli (strain K12)
PFams: EIID-AGA
Heteromeric, 283 amino acids: PaperBLAST, CDD

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for manZ.)

Q5IRC0 protein-Npi-phosphohistidine-D-mannose phosphotransferase (EC 2.7.1.191) from Streptococcus suis
PFams: EIID-AGA
303 amino acids: PaperBLAST, CDD, BRENDA::Q5IRC0
80% identical to

TC 4.A.6.1.7 / Q5M5W8 ManN, component of The glucose/mannose/2-deoxyglucose/fructose phosphotransferase systems (phosphorylates without transport), ManLMN from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
PFams: EIID-AGA
Heteromeric, 303 amino acids: PaperBLAST, CDD

TC 4.A.6.1.11 / D2BKY9 Mannose-specific PTS system, IID component, component of Mannose enzyme II complex, IIAB, IIC, IID. IIC/IID serve allows entry of some bacteriocins including pediocin (class IIa) and lactococcin A (class IIc) (Kjos et al., 2011). Transports and phosphorylates Glucose, Mannose and Glucosamine from Lactococcus lactis subsp. lactis (strain KF147)
PFams: EIID-AGA
Heteromeric, 307 amino acids: PaperBLAST, CDD, TCDB::D2BKY9
67% identical to

TC 4.A.6.1.7 / Q5M5W8 ManN, component of The glucose/mannose/2-deoxyglucose/fructose phosphotransferase systems (phosphorylates without transport), ManLMN from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
PFams: EIID-AGA
Heteromeric, 303 amino acids: PaperBLAST, CDD