Clusters of Characterized Proteins

Clustering the characterized proteins for garR (tartronate semialdehyde reductase) in D-glucuronate catabolism

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Definition of garR

• Curated proteins or TIGRFams with EC 1.1.1.60
• Curated sequence G6278-MONOMER: tartronate semialdehyde reductase 2. tartronate semialdehyde reductase 2
• Ignore hits to GFF1469 when looking for 'other' hits (2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60))
• Comment: glxR (G6278-MONOMER) is linked to this reaction (but not this EC) in ecocyc and metacyc. PGA1_c14880 (Phaeo:GFF1469) had been reannotated as a tartronate semialdehyde reductase but this is questionable.

Fetched 3 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 3 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 292-296 amino acids (not heteromeric)

Q8ZLV8 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) from Salmonella enterica subsp. enterica serovar Typhimurium
PFams: 2-Hacid_dh_C, F420_oxidored, NAD_binding_2, NAD_binding_11
296 amino acids: PaperBLAST, CDD, Compare to cluster

b3125 tartronate semialdehyde reductase (EC 1.1.1.60) from Escherichia coli K-12 substr. MG1655
P0ABQ2 tartronate semialdehyde reductase (EC 1.1.1.60) from Escherichia coli (strain K12)
GARR_ECOLI / P0ABQ2 2-hydroxy-3-oxopropionate reductase; Tartronate semialdehyde reductase; TSAR; EC 1.1.1.60 from Escherichia coli (strain K12)
PFams: 2-Hacid_dh_C, F420_oxidored, NAD_binding_2, NAD_binding_11
294 amino acids: PaperBLAST, CDD, Compare to cluster

b0509 tartronate semialdehyde reductase 2 from Escherichia coli K-12 substr. MG1655
P77161 tartronate semialdehyde reductase 2 from Escherichia coli (strain K12)
PFams: F420_oxidored, NAD_binding_2, NAD_binding_11
292 amino acids: PaperBLAST, CDD, Compare to cluster