Clusters of Characterized Proteins

Clustering the characterized proteins for braC (ABC transporter for glutamate, histidine, arginine, and other amino acids, substrate-binding component BraC) in L-glutamate catabolism

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Definition of braC

• Curated sequence Q9L3M3: BraC, component of General L- (and D-)amino acid uptake porter (transports acidic, basic, polar, semipolar and hydrophobic amino acids). The amino and carboxyl groups do not need to be α since γ-aminobutyric acid (GABA) is a substrate. The system may function with additional binding proteins since L-alanine uptake is not dependent on BraC
• Comment: In Rhizobium leguminosarum, a broad-specificity amino acid ABC transporter is known as braCDEFG. (A homologous system from Pseudomonas is thought to have a narrower substrate range.)

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Rhizobium leguminosarum

TC 3.A.1.4.3 / Q9L3M3 BraC, component of General L- (and D-)amino acid uptake porter (transports acidic, basic, polar, semipolar and hydrophobic amino acids). The amino and carboxyl groups do not need to be α since γ-aminobutyric acid (GABA) is a substrate. The system may function with additional binding proteins since L-alanine uptake is not dependent on BraC from Rhizobium leguminosarum (biovar viciae)
PFams: Peripla_BP_6, Peripla_BP_5, ANF_receptor
Heteromeric, 381 amino acids: PaperBLAST, CDD (Singleton 1)