GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for mcl ((S)-citramalyl-CoA pyruvate-lyase) in L-glutamate catabolism

Or see other characterized proteins similar to mcl

Or see all steps for L-glutamate catabolism

Or cluster curated proteins matching a keyword

Definition of mcl

Fetched 6 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 6 of these sequences

Found 2 clusters of similar sequences. Download as table or as draft rules or view by cluster

Aspergillus terreus

A0A172MLA1 (S)-citramalyl-CoA lyase (EC 4.1.3.25); (R)-citramalyl-CoA lyase (EC 4.1.3.46) from Aspergillus terreus
PFams: HpcH_HpaI
322 amino acids: PaperBLAST, CDD (Cluster 1)

Chloroflexus aurantiacus

MCLA_CHLAU / S5N020 Malyl-CoA/beta-methylmalyl-CoA/citramalyl-CoA lyase; (3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase; (3S)-citramalyl-CoA pyruvate-lyase; (S)-citramalyl-CoA lyase; Erythro-beta-methylmalyl-CoA; L-malyl-CoA lyase; EC 4.1.3.24; EC 4.1.3.25 from Chloroflexus aurantiacus
S5N020 malyl-CoA lyase (EC 4.1.3.24); (S)-citramalyl-CoA lyase (EC 4.1.3.25) from Chloroflexus aurantiacus
A9WC35 L-malyl CoA lyase subunit (EC 4.1.3.25; EC 4.1.3.24) from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
PFams: HpcH_HpaI
348 amino acids: PaperBLAST, CDD (Cluster 2)

Homo sapiens

CLYBL_HUMAN / Q8N0X4 Citramalyl-CoA lyase, mitochondrial; (3S)-malyl-CoA thioesterase; Beta-methylmalate synthase; Citrate lyase subunit beta-like protein; Citrate lyase beta-like; Malate synthase; EC 4.1.3.25; EC 3.1.2.30; EC 2.3.3.-; EC 2.3.3.9 from Homo sapiens (Human)
Q8N0X4 citrate (pro-3S)-lyase (EC 4.1.3.6) from Homo sapiens
Q8N0X4 malate/β-methylmalate synthase (EC 2.3.3.9) from Homo sapiens
PFams: HpcH_HpaI
340 amino acids: PaperBLAST, CDD (Cluster 1)

Mus musculus

CLYBL_MOUSE / Q8R4N0 Citramalyl-CoA lyase, mitochondrial; (3S)-malyl-CoA thioesterase; Beta-methylmalate synthase; Citrate lyase subunit beta-like protein, mitochondrial; Citrate lyase beta-like; Malate synthase; EC 4.1.3.25; EC 3.1.2.30; EC 2.3.3.-; EC 2.3.3.9 from Mus musculus (Mouse)
Q8R4N0 citrate (pro-3S)-lyase (EC 4.1.3.6) from Mus musculus
PFams: HpcH_HpaI, C-C_Bond_Lyase
338 amino acids: PaperBLAST, CDD (Cluster 1)

Pseudomonas aeruginosa

Q9I562 (S)-citramalyl-CoA lyase (EC 4.1.3.25) from Pseudomonas aeruginosa
PFams: HpcH_HpaI
275 amino acids: PaperBLAST, CDD (Cluster 1)

Rhodobacteraeroides

MCAL_RHOS4 / Q3J5L6 L-malyl-CoA/beta-methylmalyl-CoA lyase; (3S)-malyl-CoA/beta-methylmalyl-CoA lyase; (S)-citramalyl-CoA lyase; EC 4.1.3.24; EC 4.1.3.25 from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Q3J5L6 malyl-CoA lyase (EC 4.1.3.24) from Rhodobacter sphaeroides
PFams: HpcH_HpaI
318 amino acids: PaperBLAST, CDD (Cluster 2)

Rhodobacteraeroides (strain

MCAL_RHOS4 / Q3J5L6 L-malyl-CoA/beta-methylmalyl-CoA lyase; (3S)-malyl-CoA/beta-methylmalyl-CoA lyase; (S)-citramalyl-CoA lyase; EC 4.1.3.24; EC 4.1.3.25 from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Q3J5L6 malyl-CoA lyase (EC 4.1.3.24) from Rhodobacter sphaeroides
PFams: HpcH_HpaI
318 amino acids: PaperBLAST, CDD (Cluster 2)