Other Characterized Proteins Similar to glpF

GapMind for catabolism of small carbon sources

Other Characterized Proteins Similar to glpF

Finding the characterized proteins for glpF (glycerol facilitator glpF) in glycerol catabolism

Or see clustering for step glpF

Or see all steps for glycerol catabolism

Or cluster curated proteins matching a keyword

Definition of glpF

Curated sequence CH_024677: aquaglyceroporin. Glycerol uptake facilitator protein; Aquaglyceroporin. Glycerol facilitator, GlpF. Transports various polyols with decreasing rates as size increases (Heller et al. 1980); also transports arsenite (As(III) and antimonite (Sb(III)) (Meng et al., 2004). Oligomerization may play a role in determining the rate of transport. glycerol facilitator. glycerol facilitator
Curated sequence CH_091207: aquaporin-9. Aquaporin-9; AQP-9; Aquaglyceroporin-9. Aquaporin-9 (Aqp9) (permeable to glycerol, urea, polyols, carbamides, purines, pyrmidines, nucleosides, monocarboxylates, pentavalent methylated arsenicals and the arsenic chemotherapeutic drug, trisenox
Curated sequence CH_091783: aquaglyceroporin 1. Aquaporin 1 (permeable to water, glycerol, dihydroxyacetone and urea)
Curated sequence F9UMX3: Glycerol uptake facilitator protein 4; D/L-lactic acid transporter; Lactic acid channel
Curated sequence F9UST3: D/L-lactic acid transporter; Lactate racemization operon protein LarD; Lactic acid channel. GlpF1; transports water, dihydroxyacetone and glycerol as well as D,L-lactic acid
Curated sequence F9USY3: Glycerol uptake facilitator protein 2. GlpF2
Curated sequence F9UTW9: Glycerol uptake facilitator protein 3. GlpF3
Curated sequence F9UUB3: Glycerol uptake facilitator protein-like 5. GlpF4. Transports water, dihydroxyacetone and glycerol as well as D,L-lactic acid
Curated sequence P47862: Aquaporin-3; AQP-3; 31.4 kDa water channel protein; Aquaglyceroporin-3. Aquaporin 3. 95% identical to the human orthologue. Poorly permeable to water, but more permeable to glycerol and arsenic trioxide
Curated sequence F6QEC2: Aquaporin/glycerol facilitator of 294 aas and 6 TMSs
Curated sequence P08995: Nodulin-26 aquaporin and glycerol facilitator, NIP (de Paula Santos Martins et al. 2015). Transports NH3 5-fold better than water in Hg2+-sensitive fashion
Curated sequence P18156: Glycerol facilitator
Curated sequence P52280: Probable glycerol uptake facilitator protein
Curated sequence Q6Q1Q6: Major aquaglyceroporin, LmAQP1: transports water, glycerol, methylglyoxal, trivalent metalloids such as arsenite and antimonite, dihydroxyacetone and sugar alcohols. Also takes up the activated form or the drug, pentostam
Curated sequence Q8WPZ6: Aquaglycerolporin, Aqp (high permeability to ammonium, methylamine, glycerol and water) (Beitz et al., 2004) NH4+/NH3+CH3 transporter
Curated sequence Q9C4Z5: Hg2+-inhibitable aquaporin, AqpM (transports both water and glycerol as well as CO2) (Kozono et al., 2003; Araya-Secchi et al., 2011). Its 3-d structure has been determined to 1.7 Å. In AqpM, isoleucine replaces a key histidine residue found in the lumen of water channels, which becomes a glycine residue in aquaglyceroporins. As a result of this and other side-chain substituents in the walls of the channel, the channel is intermediate in size and exhibits differentially tuned electrostatics when compared with the other subfamilies
Ignore hits to O28846 when looking for 'other' hits (MIP family homologue)
Comment: Ignore an uncharacterized homolog from Archaeoglobus

Fetched 16 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 32 other characterized sequences. (Found 48 hits including self hits.)

Removing ignored items reduces this to 31 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for glpF.)

AQP3_MOUSE / Q8R2N1 Aquaporin-3; AQP-3; Aquaglyceroporin-3 from Mus musculus (Mouse)
PFams: MIP
292 amino acids: PaperBLAST, CDD, SwissProt::Q8R2N1
97% identical to

AQP3_RAT / P47862 Aquaporin-3; AQP-3; 31.4 kDa water channel protein; Aquaglyceroporin-3 from Rattus norvegicus (Rat)
TC 1.A.8.9.1 / P47862 Aquaporin 3. 95% identical to the human orthologue. Poorly permeable to water, but more permeable to glycerol and arsenic trioxide from Rattus norvegicus (Rat)
PFams: MIP
292 amino acids: PaperBLAST, CDD

AQP3_HUMAN / Q92482 Aquaporin-3; AQP-3; Aquaglyceroporin-3 from Homo sapiens (Human)
PFams: MIP
292 amino acids: PaperBLAST, CDD, SwissProt::Q92482
94% identical to

AQP3_PIG / A9Y006 Aquaporin-3; Aquaglyceroporin-3 from Sus scrofa (Pig)
PFams: MIP
290 amino acids: PaperBLAST, CDD, SwissProt::A9Y006
92% identical to

TC 1.A.8.9.12 / Q6IRR9 Basolateral Aqp3 of 292 aas and 6 TMSs in the frog urinary bladder from Xenopus laevis
PFams: MIP
292 amino acids: PaperBLAST, CDD, TCDB::Q6IRR9
77% identical to

AQP9_HUMAN / O43315 Aquaporin-9; AQP-9; Aquaglyceroporin-9; Small solute channel 1 from Homo sapiens (Human)
PFams: MIP
295 amino acids: PaperBLAST, CDD, SwissProt::O43315
75% identical to

AQP9_RAT / P56627 Aquaporin-9; AQP-9; Aquaglyceroporin-9 from Rattus norvegicus (Rat)
TC 1.A.8.9.2 / P56627 Aquaporin-9 (Aqp9) (permeable to glycerol, urea, polyols, carbamides, purines, pyrmidines, nucleosides, monocarboxylates, pentavalent methylated arsenicals and the arsenic chemotherapeutic drug, trisenox from Rattus norvegicus (Rat)
RF|NP_075249.1 aquaporin-9 from Rattus norvegicus
PFams: MIP
295 amino acids: PaperBLAST, CDD

NIP11_ARATH / Q8VZW1 Aquaporin NIP1-1; NOD26-like intrinsic protein 1-1; AtNIP1;1; Nodulin-26-like major intrinsic protein 1; NodLikeMip1; Protein NLM1 from Arabidopsis thaliana (Mouse-ear cress)
TC 1.A.8.12.8 / Q8VZW1 Aquaporin NIP1-1 (NOD26-like intrinsic protein 1-1) (AtNIP1;1) (Nodulin-26-like major intrinsic protein 1) (NodLikeMip1) (Protein NLM1) from Arabidopsis thaliana
PFams: MIP
296 amino acids: PaperBLAST, CDD, SwissProt::Q8VZW1
62% identical to

TC 1.A.8.12.1 / P08995 Nodulin-26 aquaporin and glycerol facilitator, NIP (de Paula Santos Martins et al. 2015). Transports NH3 5-fold better than water in Hg2+-sensitive fashion from Glycine max (Soybean)
PFams: MIP
271 amino acids: PaperBLAST, CDD

NIP12_ARATH / Q8LFP7 Aquaporin NIP1-2; NOD26-like intrinsic protein 1-2; AtNIP1;2; Nodulin-26-like major intrinsic protein 2; NodLikeMip2; Protein NLM2 from Arabidopsis thaliana (Mouse-ear cress)
TC 1.A.8.12.7 / Q8LFP7 Aquaporin NIP1-2 (NOD26-like intrinsic protein 1-2) (AtNIP1;2) (Nodulin-26-like major intrinsic protein 2) (NodLikeMip2) (Protein NLM2) from Arabidopsis thaliana
PFams: MIP
294 amino acids: PaperBLAST, CDD, SwissProt::Q8LFP7
62% identical to

NIP11_ORYSJ / Q40746 Aquaporin NIP1-1; NOD26-like intrinsic protein 1-1; OsNIP1;1 from Oryza sativa subsp. japonica (Rice)
PFams: MIP
284 amino acids: PaperBLAST, CDD, SwissProt::Q40746
65% identical to

GI|46518241 aquaglyceroporin 2 from Trypanosoma brucei brucei
PFams: MIP
312 amino acids: PaperBLAST, CDD, CharProtDB::CH_091784
56% identical to

TC 1.A.8.9.4 / Q6ZXT4 Aquaporin 1 (permeable to water, glycerol, dihydroxyacetone and urea) from Trypanosoma brucei brucei
GI|46518239 aquaglyceroporin 1 from Trypanosoma brucei brucei
PFams: MIP
321 amino acids: PaperBLAST, CDD

NIP12_ORYSJ / Q0JPT5 Aquaporin NIP1-2; NOD26-like intrinsic protein 1-2; OsNIP1;2 from Oryza sativa subsp. japonica (Rice)
PFams: MIP
303 amino acids: PaperBLAST, CDD, SwissProt::Q0JPT5
52% identical to

NIP21_ARATH / Q8W037 Aquaporin NIP2-1; NOD26-like intrinsic protein 2-1; AtNIP2;1; Nodulin-26-like major intrinsic protein 4; NodLikeMip4; Protein NLM4 from Arabidopsis thaliana (Mouse-ear cress)
TC 1.A.8.12.4 / Q8W037 The root-expressed MIP transporter of lactic acid, NIP2;1 (Nod26-like MIP-4; NLM4) (induced by water logging and anoxic stress; shows minimal water and glycerol transport). It may play a role in adaptation to lactic fermentaion under anaerobic stress (Choi and Roberts, 2007). Lactic acid transport is induced by anoxic stress from Arabidopsis thaliana (Mouse-ear cress)
RF|NP_180986.1 aquaporin NIP2-1 from Arabidopsis thaliana
PFams: MIP
288 amino acids: PaperBLAST, CDD, CharProtDB::CH_091408
51% identical to

AQP10_HUMAN / Q96PS8 Aquaporin-10; AQP-10; Aquaglyceroporin-10; Small intestine aquaporin from Homo sapiens (Human)
TC 1.A.8.9.5 / Q96PS8 Aquaporin 10 from Homo sapiens
PFams: MIP
301 amino acids: PaperBLAST, CDD, SwissProt::Q96PS8
51% identical to

AQP7_MOUSE / O54794 Aquaporin-7; AQP-7; Aquaglyceroporin-7 from Mus musculus (Mouse)
PFams: MIP
303 amino acids: PaperBLAST, CDD, SwissProt::O54794
47% identical to

AQP7_RAT / P56403 Aquaporin-7; AQP-7; Aquaglyceroporin-7 from Rattus norvegicus (Rat)
PFams: MIP
269 amino acids: PaperBLAST, CDD, SwissProt::P56403
49% identical to

AQP7_HUMAN / O14520 Aquaporin-7; AQP-7; Aquaglyceroporin-7; Aquaporin adipose; AQPap; Aquaporin-7-like from Homo sapiens (Human)
PFams: MIP
342 amino acids: PaperBLAST, CDD, SwissProt::O14520
47% identical to

NIP31_ORYSJ / Q0IWF3 Aquaporin NIP3-1; NOD26-like intrinsic protein 3-1; OsNIP3;1 from Oryza sativa subsp. japonica (Rice)
PFams: MIP
311 amino acids: PaperBLAST, CDD, SwissProt::Q0IWF3
51% identical to

NIP14_ORYSJ / Q5Z9E2 Aquaporin NIP1-4; NOD26-like intrinsic protein 1-4; OsNIP1;4 from Oryza sativa subsp. japonica (Rice)
PFams: MIP
273 amino acids: PaperBLAST, CDD, SwissProt::Q5Z9E2
51% identical to

AQP7_MILTA / G5CTG4 Aquaporin-7; AQP-7 from Milnesium tardigradum (Water bear) (Tardigrade)
PFams: MIP
315 amino acids: PaperBLAST, CDD, SwissProt::G5CTG4
43% identical to