GapMind for catabolism of small carbon sources

 

Other Characterized Proteins Similar to SLC38A3

Finding the characterized proteins for SLC38A3 (L-histidine:Na+ symporter) in L-histidine catabolism

Or see clustering for step SLC38A3

Or see all steps for L-histidine catabolism

Or cluster curated proteins matching a keyword

Definition of SLC38A3

Fetched 2 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 14 other characterized sequences. (Found 16 hits including self hits.)

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for SLC38A3.)

S38A3_RAT / Q9JHZ9 Sodium-coupled neutral amino acid transporter 3; N-system amino acid transporter 1; Na(+)-coupled neutral amino acid transporter 3; Solute carrier family 38 member 3; System N amino acid transporter 1 from Rattus norvegicus (Rat)
PFams: Aa_trans
504 amino acids: PaperBLAST, CDD, SwissProt::Q9JHZ9
96% identical to

S38A3_MOUSE / Q9DCP2 Sodium-coupled neutral amino acid transporter 3; N-system amino acid transporter 1; Na(+)-coupled neutral amino acid transporter 3; Solute carrier family 38 member 3; mNAT; System N amino acid transporter 1 from Mus musculus (Mouse)
TC 2.A.18.6.2 / Q9DCP2 Liver histidine and glutamine specific system N-like, Na+-dependent amino acid transporter, mNAT. Also called SNAT3. SNAT3 trafficking occurs in a dynamin-independent manner and is influenced by caveolin
RF|NP_076294.2 sodium-coupled neutral amino acid transporter 3 from Mus musculus
PFams: Aa_trans
505 amino acids: PaperBLAST, CDD

S38A5_HUMAN / Q8WUX1 Sodium-coupled neutral amino acid transporter 5; Solute carrier family 38 member 5; System N transporter 2 from Homo sapiens (Human)
TC 2.A.18.6.15 / Q8WUX1 Neutral amino acid transporter 5 (Solute carrier family 38 member 5, SNAT5) (System N transporter 2, SN2) from Homo sapiens
PFams: Aa_trans
472 amino acids: PaperBLAST, CDD, SwissProt::Q8WUX1
61% identical to

S38A3_MOUSE / Q9DCP2 Sodium-coupled neutral amino acid transporter 3; N-system amino acid transporter 1; Na(+)-coupled neutral amino acid transporter 3; Solute carrier family 38 member 3; mNAT; System N amino acid transporter 1 from Mus musculus (Mouse)
TC 2.A.18.6.2 / Q9DCP2 Liver histidine and glutamine specific system N-like, Na+-dependent amino acid transporter, mNAT. Also called SNAT3. SNAT3 trafficking occurs in a dynamin-independent manner and is influenced by caveolin
RF|NP_076294.2 sodium-coupled neutral amino acid transporter 3 from Mus musculus
PFams: Aa_trans
505 amino acids: PaperBLAST, CDD

S38A5_MOUSE / Q3U1J0 Sodium-coupled neutral amino acid transporter 5; Solute carrier family 38 member 5; System N transporter 2 from Mus musculus (Mouse)
PFams: Aa_trans
479 amino acids: PaperBLAST, CDD, SwissProt::Q3U1J0
60% identical to

S38A3_HUMAN / Q99624 Sodium-coupled neutral amino acid transporter 3; N-system amino acid transporter 1; Na(+)-coupled neutral amino acid transporter 3; Solute carrier family 38 member 3; System N amino acid transporter 1 from Homo sapiens (Human)
TC 2.A.18.6.3 / Q99624 System N1, SNAT3 [glutamine/histidine/asparagine/alanine]:[Na+ + H+] sym/antiporter (1 aa + 2 Na+ cotransported against 1 H+ antiported out) (probable orthologue of mNAT). Li+ can substitute for Na+; system N1 can function bidirectionally. SNAT3 is a primarily a glutamine transporter required for amino acid homeostasis. Loss cannot be compensated, suggesting that this transporter is a major route of glutamine transport in the liver, brain, and kidney from Homo sapiens (Human)
RF|NP_006832.1 sodium-coupled neutral amino acid transporter 3 from Homo sapiens
PFams: Aa_trans
504 amino acids: PaperBLAST, CDD

S38A5_RAT / A2VCW5 Sodium-coupled neutral amino acid transporter 5; Solute carrier family 38 member 5; System N transporter 2 from Rattus norvegicus (Rat)
TC 2.A.18.6.8 / A2VCW5 Second subtype of system N; glutamine transporter, SN2. Prevalent in liver, but detectable in other tissues. Amino acid uptake is coupled to Na+ influx and H+ efflux
PFams: Aa_trans
479 amino acids: PaperBLAST, CDD, SwissProt::A2VCW5
60% identical to

S38A3_MOUSE / Q9DCP2 Sodium-coupled neutral amino acid transporter 3; N-system amino acid transporter 1; Na(+)-coupled neutral amino acid transporter 3; Solute carrier family 38 member 3; mNAT; System N amino acid transporter 1 from Mus musculus (Mouse)
TC 2.A.18.6.2 / Q9DCP2 Liver histidine and glutamine specific system N-like, Na+-dependent amino acid transporter, mNAT. Also called SNAT3. SNAT3 trafficking occurs in a dynamin-independent manner and is influenced by caveolin
RF|NP_076294.2 sodium-coupled neutral amino acid transporter 3 from Mus musculus
PFams: Aa_trans
505 amino acids: PaperBLAST, CDD

S38A2_HUMAN / Q96QD8 Sodium-coupled neutral amino acid transporter 2; Amino acid transporter A2; Protein 40-9-1; Solute carrier family 38 member 2; System A amino acid transporter 2; System A transporter 1; System N amino acid transporter 2 from Homo sapiens (Human)
TC 2.A.18.6.5 / Q96QD8 Na+-dependent system A-like transporter, System A2 or ATA2 (transports neutral amino acids with decreasing affinity in the order: MeAIB, Ala, Gly, Ser, Pro, Met, Asn, Gln, Thr, Leu and Phe). The neuronal system A2 has been reported to transport Asn and Gln with higher affinity than for other neutral amino acids. [ATA2 is stored in the Golgi network and released by insulin stimulus in adipocytes (Hatanaka et al., 2006a).] Its levels are regulated by ubiquitin ligase, Nedd4-2, which causes endocytotic sequestration and proteosomal degradation (Hatanaka et al., 2006b). SNAT2 also functions as a mammalian amino acid transceptor (transporter/receptor), acting in an autoregulatory gene expression pathway (Hyde et al., 2007). It also mediates an anion leak conductance that is differentially inhibited by transported substrates (Zhang and Grewer, 2007). Also transports homocysteine
PFams: Aa_trans
506 amino acids: PaperBLAST, CDD, SwissProt::Q96QD8
56% identical to

S38A3_HUMAN / Q99624 Sodium-coupled neutral amino acid transporter 3; N-system amino acid transporter 1; Na(+)-coupled neutral amino acid transporter 3; Solute carrier family 38 member 3; System N amino acid transporter 1 from Homo sapiens (Human)
TC 2.A.18.6.3 / Q99624 System N1, SNAT3 [glutamine/histidine/asparagine/alanine]:[Na+ + H+] sym/antiporter (1 aa + 2 Na+ cotransported against 1 H+ antiported out) (probable orthologue of mNAT). Li+ can substitute for Na+; system N1 can function bidirectionally. SNAT3 is a primarily a glutamine transporter required for amino acid homeostasis. Loss cannot be compensated, suggesting that this transporter is a major route of glutamine transport in the liver, brain, and kidney from Homo sapiens (Human)
RF|NP_006832.1 sodium-coupled neutral amino acid transporter 3 from Homo sapiens
PFams: Aa_trans
504 amino acids: PaperBLAST, CDD

S38A2_RAT / Q9JHE5 Sodium-coupled neutral amino acid transporter 2; Amino acid transporter A2; Solute carrier family 38 member 2; System A amino acid transporter 2; System A transporter 1; System N amino acid transporter 2 from Rattus norvegicus (Rat)
TC 2.A.18.6.4 / Q9JHE5 Plasma membrane System A-like neutral amino acid transporter, SA1, SAT2 or SNAT2 (transports small, neutral aliphatic amino acids including α-(methylamino)isobutyrate, mAIB with Na+ (1:1 stoichiometry; Km = 200-500 μM)). Asparagine 82 controls the interaction of Na+ with the transporter (Zhang and Grewer, 2007). The C-terminal domain regulates transport activity through a voltage-dependent process (Zhang et al., 2011). An 11 TMS topology has been experimentally demonstrated from Rattus norvegicus (Rat)
PFams: Aa_trans
504 amino acids: PaperBLAST, CDD, SwissProt::Q9JHE5
56% identical to

S38A3_MOUSE / Q9DCP2 Sodium-coupled neutral amino acid transporter 3; N-system amino acid transporter 1; Na(+)-coupled neutral amino acid transporter 3; Solute carrier family 38 member 3; mNAT; System N amino acid transporter 1 from Mus musculus (Mouse)
TC 2.A.18.6.2 / Q9DCP2 Liver histidine and glutamine specific system N-like, Na+-dependent amino acid transporter, mNAT. Also called SNAT3. SNAT3 trafficking occurs in a dynamin-independent manner and is influenced by caveolin
RF|NP_076294.2 sodium-coupled neutral amino acid transporter 3 from Mus musculus
PFams: Aa_trans
505 amino acids: PaperBLAST, CDD

S38A2_MOUSE / Q8CFE6 Sodium-coupled neutral amino acid transporter 2; Amino acid transporter A2; Solute carrier family 38 member 2; System A amino acid transporter 2; System A transporter 1; System N amino acid transporter 2 from Mus musculus (Mouse)
PFams: Aa_trans
504 amino acids: PaperBLAST, CDD, SwissProt::Q8CFE6
56% identical to

S38A3_MOUSE / Q9DCP2 Sodium-coupled neutral amino acid transporter 3; N-system amino acid transporter 1; Na(+)-coupled neutral amino acid transporter 3; Solute carrier family 38 member 3; mNAT; System N amino acid transporter 1 from Mus musculus (Mouse)
TC 2.A.18.6.2 / Q9DCP2 Liver histidine and glutamine specific system N-like, Na+-dependent amino acid transporter, mNAT. Also called SNAT3. SNAT3 trafficking occurs in a dynamin-independent manner and is influenced by caveolin
RF|NP_076294.2 sodium-coupled neutral amino acid transporter 3 from Mus musculus
PFams: Aa_trans
505 amino acids: PaperBLAST, CDD

S38A4_RAT / Q9EQ25 Sodium-coupled neutral amino acid transporter 4; Amino acid transporter A3; Na(+)-coupled neutral amino acid transporter 4; Solute carrier family 38 member 4; System A amino acid transporter 3 from Rattus norvegicus (Rat)
TC 2.A.18.6.7 / Q9EQ25 The Na-dependent alanine/α-(methylamino) isobutyric acid-transporting system A, ATA3 or SNAT4 from Rattus norvegicus (Rat)
GI|12017941 sodium-coupled neutral amino acid transporter 4 from Rattus norvegicus
PFams: Aa_trans, Aa_trans
547 amino acids: PaperBLAST, CDD, SwissProt::Q9EQ25
54% identical to

S38A3_HUMAN / Q99624 Sodium-coupled neutral amino acid transporter 3; N-system amino acid transporter 1; Na(+)-coupled neutral amino acid transporter 3; Solute carrier family 38 member 3; System N amino acid transporter 1 from Homo sapiens (Human)
TC 2.A.18.6.3 / Q99624 System N1, SNAT3 [glutamine/histidine/asparagine/alanine]:[Na+ + H+] sym/antiporter (1 aa + 2 Na+ cotransported against 1 H+ antiported out) (probable orthologue of mNAT). Li+ can substitute for Na+; system N1 can function bidirectionally. SNAT3 is a primarily a glutamine transporter required for amino acid homeostasis. Loss cannot be compensated, suggesting that this transporter is a major route of glutamine transport in the liver, brain, and kidney from Homo sapiens (Human)
RF|NP_006832.1 sodium-coupled neutral amino acid transporter 3 from Homo sapiens
PFams: Aa_trans
504 amino acids: PaperBLAST, CDD

S38A1_HUMAN / Q9H2H9 Sodium-coupled neutral amino acid transporter 1; Amino acid transporter A1; N-system amino acid transporter 2; Solute carrier family 38 member 1; System A amino acid transporter 1; System N amino acid transporter 1 from Homo sapiens (Human)
TC 2.A.18.6.14 / Q9H2H9 Sodium-coupled neutral amino acid transporter 1 (Amino acid transporter A1; SLC38A1; SNAT1; N-system amino acid transporter 2; Solute carrier family 38 member 1; System A amino acid transporter 1; System N amino acid transporter 1) from Homo sapiens
PFams: Aa_trans
487 amino acids: PaperBLAST, CDD, SwissProt::Q9H2H9
50% identical to

S38A3_HUMAN / Q99624 Sodium-coupled neutral amino acid transporter 3; N-system amino acid transporter 1; Na(+)-coupled neutral amino acid transporter 3; Solute carrier family 38 member 3; System N amino acid transporter 1 from Homo sapiens (Human)
TC 2.A.18.6.3 / Q99624 System N1, SNAT3 [glutamine/histidine/asparagine/alanine]:[Na+ + H+] sym/antiporter (1 aa + 2 Na+ cotransported against 1 H+ antiported out) (probable orthologue of mNAT). Li+ can substitute for Na+; system N1 can function bidirectionally. SNAT3 is a primarily a glutamine transporter required for amino acid homeostasis. Loss cannot be compensated, suggesting that this transporter is a major route of glutamine transport in the liver, brain, and kidney from Homo sapiens (Human)
RF|NP_006832.1 sodium-coupled neutral amino acid transporter 3 from Homo sapiens
PFams: Aa_trans
504 amino acids: PaperBLAST, CDD

S38A1_RAT / Q9JM15 Sodium-coupled neutral amino acid transporter 1; Amino acid transporter A1; rATA1; Glutamine transporter; N-system amino acid transporter 2; Solute carrier family 38 member 1; System A amino acid transporter 1; System A transporter 2; System N amino acid transporter 1 from Rattus norvegicus (Rat)
TC 2.A.18.6.1 / Q9JM15 Neuronal glutamine (System A-like) transporter, GlnT from Rattus norvegicus (Rat)
PFams: Aa_trans
485 amino acids: PaperBLAST, CDD, SwissProt::Q9JM15
53% identical to

S38A3_HUMAN / Q99624 Sodium-coupled neutral amino acid transporter 3; N-system amino acid transporter 1; Na(+)-coupled neutral amino acid transporter 3; Solute carrier family 38 member 3; System N amino acid transporter 1 from Homo sapiens (Human)
TC 2.A.18.6.3 / Q99624 System N1, SNAT3 [glutamine/histidine/asparagine/alanine]:[Na+ + H+] sym/antiporter (1 aa + 2 Na+ cotransported against 1 H+ antiported out) (probable orthologue of mNAT). Li+ can substitute for Na+; system N1 can function bidirectionally. SNAT3 is a primarily a glutamine transporter required for amino acid homeostasis. Loss cannot be compensated, suggesting that this transporter is a major route of glutamine transport in the liver, brain, and kidney from Homo sapiens (Human)
RF|NP_006832.1 sodium-coupled neutral amino acid transporter 3 from Homo sapiens
PFams: Aa_trans
504 amino acids: PaperBLAST, CDD

S38A1_MOUSE / Q8K2P7 Sodium-coupled neutral amino acid transporter 1; Amino acid transporter A1; MNat2; N-system amino acid transporter 2; Solute carrier family 38 member 1; System A amino acid transporter 1; System N amino acid transporter 1 from Mus musculus (Mouse)
PFams: Aa_trans
485 amino acids: PaperBLAST, CDD, SwissProt::Q8K2P7
53% identical to

S38A3_HUMAN / Q99624 Sodium-coupled neutral amino acid transporter 3; N-system amino acid transporter 1; Na(+)-coupled neutral amino acid transporter 3; Solute carrier family 38 member 3; System N amino acid transporter 1 from Homo sapiens (Human)
TC 2.A.18.6.3 / Q99624 System N1, SNAT3 [glutamine/histidine/asparagine/alanine]:[Na+ + H+] sym/antiporter (1 aa + 2 Na+ cotransported against 1 H+ antiported out) (probable orthologue of mNAT). Li+ can substitute for Na+; system N1 can function bidirectionally. SNAT3 is a primarily a glutamine transporter required for amino acid homeostasis. Loss cannot be compensated, suggesting that this transporter is a major route of glutamine transport in the liver, brain, and kidney from Homo sapiens (Human)
RF|NP_006832.1 sodium-coupled neutral amino acid transporter 3 from Homo sapiens
PFams: Aa_trans
504 amino acids: PaperBLAST, CDD

TC 2.A.18.6.11 / Q8IZM9 SLC38 member 6, SNAT6. Na+-dependent synaptic vesicle amino acid release porter (Gasnier, 2004) (transports amino acids, glutamine, glycine and γ-amino butyric acid (GABA)) from Homo sapiens
PFams: Aa_trans
456 amino acids: PaperBLAST, CDD, TCDB::Q8IZM9
47% identical to

S38A3_MOUSE / Q9DCP2 Sodium-coupled neutral amino acid transporter 3; N-system amino acid transporter 1; Na(+)-coupled neutral amino acid transporter 3; Solute carrier family 38 member 3; mNAT; System N amino acid transporter 1 from Mus musculus (Mouse)
TC 2.A.18.6.2 / Q9DCP2 Liver histidine and glutamine specific system N-like, Na+-dependent amino acid transporter, mNAT. Also called SNAT3. SNAT3 trafficking occurs in a dynamin-independent manner and is influenced by caveolin
RF|NP_076294.2 sodium-coupled neutral amino acid transporter 3 from Mus musculus
PFams: Aa_trans
505 amino acids: PaperBLAST, CDD

S38A6_MOUSE / G3UVW3 Probable sodium-coupled neutral amino acid transporter 6; Na(+)-coupled neutral amino acid transporter 6; Solute carrier family 38 member 6 from Mus musculus (Mouse)
PFams: Aa_trans
457 amino acids: PaperBLAST, CDD, SwissProt::G3UVW3
47% identical to

S38A3_MOUSE / Q9DCP2 Sodium-coupled neutral amino acid transporter 3; N-system amino acid transporter 1; Na(+)-coupled neutral amino acid transporter 3; Solute carrier family 38 member 3; mNAT; System N amino acid transporter 1 from Mus musculus (Mouse)
TC 2.A.18.6.2 / Q9DCP2 Liver histidine and glutamine specific system N-like, Na+-dependent amino acid transporter, mNAT. Also called SNAT3. SNAT3 trafficking occurs in a dynamin-independent manner and is influenced by caveolin
RF|NP_076294.2 sodium-coupled neutral amino acid transporter 3 from Mus musculus
PFams: Aa_trans
505 amino acids: PaperBLAST, CDD

S38A4_HUMAN / Q969I6 Sodium-coupled neutral amino acid transporter 4; Amino acid transporter A3; Na(+)-coupled neutral amino acid transporter 4; Solute carrier family 38 member 4; System A amino acid transporter 3; System N amino acid transporter 3 from Homo sapiens (Human)
TC 2.A.18.6.17 / Q969I6 Sodium-coupled neutral amino acid transporter 4 (Amino acid transporter A3) (Na(+)-coupled neutral amino acid transporter 4) (Solute carrier family 38 member 4) (System A amino acid transporter 3) (System N amino acid transporter 3) from Homo sapiens
PFams: Aa_trans, Aa_trans
547 amino acids: PaperBLAST, CDD, SwissProt::Q969I6
40% identical to

S38A3_MOUSE / Q9DCP2 Sodium-coupled neutral amino acid transporter 3; N-system amino acid transporter 1; Na(+)-coupled neutral amino acid transporter 3; Solute carrier family 38 member 3; mNAT; System N amino acid transporter 1 from Mus musculus (Mouse)
TC 2.A.18.6.2 / Q9DCP2 Liver histidine and glutamine specific system N-like, Na+-dependent amino acid transporter, mNAT. Also called SNAT3. SNAT3 trafficking occurs in a dynamin-independent manner and is influenced by caveolin
RF|NP_076294.2 sodium-coupled neutral amino acid transporter 3 from Mus musculus
PFams: Aa_trans
505 amino acids: PaperBLAST, CDD