Other Characterized Proteins Similar to hisM

Finding the characterized proteins for hisM (L-histidine ABC transporter, permease component 1 (HisM)) in L-histidine catabolism

Or see clustering for step hisM

Or see all steps for L-histidine catabolism

Or cluster curated proteins matching a keyword

Definition of hisM

• Curated sequence P0A2I7: Histidine transport system permease protein HisM. Histidine transport system permease protein HisM aka STM2352, component of Histidine/arginine/lysine/ornithine porter (Heuveling et al. 2014). In contrast to some homologous homodimeric systems, the heterodimeric histidine transporter of Salmonella enterica Typhimurium
• Curated sequence P0AEU3: Histidine transport system permease protein HisM. Histidine transport system permease protein HisM, component of Histidine/Arginine/Lysine (basic amino acid) uptake porter, HisJ/ArgT/HisP/HisM/HisQ [R, R, C, M, M, respectively] (Gilson et al. 1982). HisJ binds L-His (preferred), but 1-methyl-L-His and 3-methyl-L-His also bind, while the dipeptide carnosine binds weakly; D-histidine and the histidine degradation products, histamine, urocanic acid and imidazole do not bind. L-Arg, homo-L-Arg, and post-translationally modified methylated Arg-analogs also bind with the exception of symmetric dimethylated-L-Arg. L-Lys and L-Orn show weaker interactions with HisJ and methylated and acetylated Lys variants show poor binding.The carboxylate groups of these amino acids and their variants are essential. lysine/arginine/ornithine ABC transporter / histidine ABC transporter, membrane subunit HisM (EC 7.4.2.1)
• Curated sequence Q9HU29: Amino acid (Lysine/arginine/ornithine/histidine/octopine) ABC transporter membrane protein, component of Amino acid transporter, PA5152-PA5155. Probably transports numerous amino acids including lysine, arginine, histidine, D-alanine and D-valine (Johnson et al. 2008). Regulated by ArgR
• Ignore hits to AO356_09910 when looking for 'other' hits (ABC transporter for L-Lysine, permease component 2)

Fetched 3 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 12 other characterized sequences. (Found 15 hits including self hits.)

Removing ignored items reduces this to 11 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for hisM.)

BPHYT_RS07680 ABC transporter for L-Arginine, permease component 1 from Burkholderia phytofirmans PsJN
PFams: BPD_transp_1
Heteromeric, 237 amino acids: PaperBLAST, CDD, reanno::BFirm:BPHYT_RS07680
63% identical to

HISM_SALTY / P0A2I7 Histidine transport system permease protein HisM from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
TC 3.A.1.3.1 / P0A2I7 Histidine transport system permease protein HisM aka STM2352, component of Histidine/arginine/lysine/ornithine porter (Heuveling et al. 2014). In contrast to some homologous homodimeric systems, the heterodimeric histidine transporter of Salmonella enterica Typhimurium from Salmonella typhimurium
PFams: BPD_transp_1
Heteromeric, 235 amino acids: PaperBLAST, CDD

AO356_05505 ABC transporter for L-Lysine, permease component 2 from Pseudomonas fluorescens FW300-N2C3
PFams: BPD_transp_1
Heteromeric, 236 amino acids: PaperBLAST, CDD, reanno::pseudo5_N2C3_1:AO356_05505
58% identical to

b2307 lysine/arginine/ornithine ABC transporter / histidine ABC transporter, membrane subunit HisM (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655
HISM_ECOLI / P0AEU3 Histidine transport system permease protein HisM from Escherichia coli (strain K12)
TC 3.A.1.3.29 / P0AEU3 Histidine transport system permease protein HisM, component of Histidine/Arginine/Lysine (basic amino acid) uptake porter, HisJ/ArgT/HisP/HisM/HisQ [R, R, C, M, M, respectively] (Gilson et al. 1982). HisJ binds L-His (preferred), but 1-methyl-L-His and 3-methyl-L-His also bind, while the dipeptide carnosine binds weakly; D-histidine and the histidine degradation products, histamine, urocanic acid and imidazole do not bind. L-Arg, homo-L-Arg, and post-translationally modified methylated Arg-analogs also bind with the exception of symmetric dimethylated-L-Arg. L-Lys and L-Orn show weaker interactions with HisJ and methylated and acetylated Lys variants show poor binding.The carboxylate groups of these amino acids and their variants are essential from Escherichia coli (strain K12)
PFams: BPD_transp_1
Heteromeric, 238 amino acids: PaperBLAST, CDD

Pf6N2E2_2960 ABC transporter for L-Lysine, permease component 2 from Pseudomonas fluorescens FW300-N2E2
PFams: BPD_transp_1
Heteromeric, 236 amino acids: PaperBLAST, CDD, reanno::pseudo6_N2E2:Pf6N2E2_2960
57% identical to

b2307 lysine/arginine/ornithine ABC transporter / histidine ABC transporter, membrane subunit HisM (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655
HISM_ECOLI / P0AEU3 Histidine transport system permease protein HisM from Escherichia coli (strain K12)
TC 3.A.1.3.29 / P0AEU3 Histidine transport system permease protein HisM, component of Histidine/Arginine/Lysine (basic amino acid) uptake porter, HisJ/ArgT/HisP/HisM/HisQ [R, R, C, M, M, respectively] (Gilson et al. 1982). HisJ binds L-His (preferred), but 1-methyl-L-His and 3-methyl-L-His also bind, while the dipeptide carnosine binds weakly; D-histidine and the histidine degradation products, histamine, urocanic acid and imidazole do not bind. L-Arg, homo-L-Arg, and post-translationally modified methylated Arg-analogs also bind with the exception of symmetric dimethylated-L-Arg. L-Lys and L-Orn show weaker interactions with HisJ and methylated and acetylated Lys variants show poor binding.The carboxylate groups of these amino acids and their variants are essential from Escherichia coli (strain K12)
PFams: BPD_transp_1
Heteromeric, 238 amino acids: PaperBLAST, CDD

TC 3.A.1.3.11 / O50183 AotP aka AotM aka PA0890, component of Arginine/ornithine (but not lysine) porter from Pseudomonas aeruginosa
PFams: BPD_transp_1
Heteromeric, 232 amino acids: PaperBLAST, CDD, TCDB::O50183
47% identical to

HISM_SALTY / P0A2I7 Histidine transport system permease protein HisM from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
TC 3.A.1.3.1 / P0A2I7 Histidine transport system permease protein HisM aka STM2352, component of Histidine/arginine/lysine/ornithine porter (Heuveling et al. 2014). In contrast to some homologous homodimeric systems, the heterodimeric histidine transporter of Salmonella enterica Typhimurium from Salmonella typhimurium
PFams: BPD_transp_1
Heteromeric, 235 amino acids: PaperBLAST, CDD

PS417_21735 ABC transporter for L-Arginine, permease component 2 from Pseudomonas simiae WCS417
PFams: BPD_transp_1
Heteromeric, 232 amino acids: PaperBLAST, CDD, reanno::WCS417:GFF4243
47% identical to

TC 3.A.1.3.23 / Q9HU29 Amino acid (Lysine/arginine/ornithine/histidine/octopine) ABC transporter membrane protein, component of Amino acid transporter, PA5152-PA5155. Probably transports numerous amino acids including lysine, arginine, histidine, D-alanine and D-valine (Johnson et al. 2008). Regulated by ArgR from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
PFams: BPD_transp_1
Heteromeric, 230 amino acids: PaperBLAST, CDD

AO353_03045 ABC transporter for L-Arginine and L-Citrulline, permease component 1 from Pseudomonas fluorescens FW300-N2E3
PFams: BPD_transp_1
Heteromeric, 232 amino acids: PaperBLAST, CDD, reanno::pseudo3_N2E3:AO353_03045
48% identical to

b2307 lysine/arginine/ornithine ABC transporter / histidine ABC transporter, membrane subunit HisM (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655
HISM_ECOLI / P0AEU3 Histidine transport system permease protein HisM from Escherichia coli (strain K12)
TC 3.A.1.3.29 / P0AEU3 Histidine transport system permease protein HisM, component of Histidine/Arginine/Lysine (basic amino acid) uptake porter, HisJ/ArgT/HisP/HisM/HisQ [R, R, C, M, M, respectively] (Gilson et al. 1982). HisJ binds L-His (preferred), but 1-methyl-L-His and 3-methyl-L-His also bind, while the dipeptide carnosine binds weakly; D-histidine and the histidine degradation products, histamine, urocanic acid and imidazole do not bind. L-Arg, homo-L-Arg, and post-translationally modified methylated Arg-analogs also bind with the exception of symmetric dimethylated-L-Arg. L-Lys and L-Orn show weaker interactions with HisJ and methylated and acetylated Lys variants show poor binding.The carboxylate groups of these amino acids and their variants are essential from Escherichia coli (strain K12)
PFams: BPD_transp_1
Heteromeric, 238 amino acids: PaperBLAST, CDD

AO356_18710 L-Arginine ABC transporter, permease component 1 from Pseudomonas fluorescens FW300-N2C3
PFams: BPD_transp_1
Heteromeric, 232 amino acids: PaperBLAST, CDD, reanno::pseudo5_N2C3_1:AO356_18710
45% identical to

TC 3.A.1.3.23 / Q9HU29 Amino acid (Lysine/arginine/ornithine/histidine/octopine) ABC transporter membrane protein, component of Amino acid transporter, PA5152-PA5155. Probably transports numerous amino acids including lysine, arginine, histidine, D-alanine and D-valine (Johnson et al. 2008). Regulated by ArgR from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
PFams: BPD_transp_1
Heteromeric, 230 amino acids: PaperBLAST, CDD

Pf1N1B4_3433 ABC transporter for L-Arginine and L-Citrulline, permease component 2 from Pseudomonas fluorescens FW300-N1B4
PFams: BPD_transp_1
Heteromeric, 232 amino acids: PaperBLAST, CDD, reanno::pseudo1_N1B4:Pf1N1B4_3433
48% identical to

b2307 lysine/arginine/ornithine ABC transporter / histidine ABC transporter, membrane subunit HisM (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655
HISM_ECOLI / P0AEU3 Histidine transport system permease protein HisM from Escherichia coli (strain K12)
TC 3.A.1.3.29 / P0AEU3 Histidine transport system permease protein HisM, component of Histidine/Arginine/Lysine (basic amino acid) uptake porter, HisJ/ArgT/HisP/HisM/HisQ [R, R, C, M, M, respectively] (Gilson et al. 1982). HisJ binds L-His (preferred), but 1-methyl-L-His and 3-methyl-L-His also bind, while the dipeptide carnosine binds weakly; D-histidine and the histidine degradation products, histamine, urocanic acid and imidazole do not bind. L-Arg, homo-L-Arg, and post-translationally modified methylated Arg-analogs also bind with the exception of symmetric dimethylated-L-Arg. L-Lys and L-Orn show weaker interactions with HisJ and methylated and acetylated Lys variants show poor binding.The carboxylate groups of these amino acids and their variants are essential from Escherichia coli (strain K12)
PFams: BPD_transp_1
Heteromeric, 238 amino acids: PaperBLAST, CDD

Pf6N2E2_5662 L-Arginine ABC transporter, permease protein AotM from Pseudomonas fluorescens FW300-N2E2
PFams: BPD_transp_1
232 amino acids: PaperBLAST, CDD, reanno::pseudo6_N2E2:Pf6N2E2_5662
44% identical to

TC 3.A.1.3.23 / Q9HU29 Amino acid (Lysine/arginine/ornithine/histidine/octopine) ABC transporter membrane protein, component of Amino acid transporter, PA5152-PA5155. Probably transports numerous amino acids including lysine, arginine, histidine, D-alanine and D-valine (Johnson et al. 2008). Regulated by ArgR from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
PFams: BPD_transp_1
Heteromeric, 230 amino acids: PaperBLAST, CDD

TC 3.A.1.3.5 / P35114 OCM1 aka OccM, component of Octopine porter from Agrobacterium tumefaciens
PFams: BPD_transp_1
Heteromeric, 245 amino acids: PaperBLAST, CDD, TCDB::P35114
47% identical to

TC 3.A.1.3.23 / Q9HU29 Amino acid (Lysine/arginine/ornithine/histidine/octopine) ABC transporter membrane protein, component of Amino acid transporter, PA5152-PA5155. Probably transports numerous amino acids including lysine, arginine, histidine, D-alanine and D-valine (Johnson et al. 2008). Regulated by ArgR from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
PFams: BPD_transp_1
Heteromeric, 230 amino acids: PaperBLAST, CDD

TC 3.A.1.3.6 / P35113 NocM aka ATU6025 aka AGR_PTI_65, component of Nopaline porter from Agrobacterium tumefaciens
PFams: BPD_transp_1
Heteromeric, 241 amino acids: PaperBLAST, CDD, TCDB::P35113
40% identical to

HISM_SALTY / P0A2I7 Histidine transport system permease protein HisM from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
TC 3.A.1.3.1 / P0A2I7 Histidine transport system permease protein HisM aka STM2352, component of Histidine/arginine/lysine/ornithine porter (Heuveling et al. 2014). In contrast to some homologous homodimeric systems, the heterodimeric histidine transporter of Salmonella enterica Typhimurium from Salmonella typhimurium
PFams: BPD_transp_1
Heteromeric, 235 amino acids: PaperBLAST, CDD

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for hisM.)

AO356_09910 ABC transporter for L-Lysine, permease component 2 from Pseudomonas fluorescens FW300-N2C3
PFams: BPD_transp_1
Heteromeric, 229 amino acids: PaperBLAST, CDD, reanno::pseudo5_N2C3_1:AO356_09910
71% identical to

TC 3.A.1.3.23 / Q9HU29 Amino acid (Lysine/arginine/ornithine/histidine/octopine) ABC transporter membrane protein, component of Amino acid transporter, PA5152-PA5155. Probably transports numerous amino acids including lysine, arginine, histidine, D-alanine and D-valine (Johnson et al. 2008). Regulated by ArgR from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
PFams: BPD_transp_1
Heteromeric, 230 amino acids: PaperBLAST, CDD