Sequence Cluster id id2 desc organism isHeteromeric 1 Cluster1 BRENDA::P28790 acetyl-CoA C-acyltransferase (EC 2.3.1.16) Pseudomonas fragi 2 Cluster1 BRENDA::A4YEH9 acetyl-CoA C-acetyltransferase (EC 2.3.1.9) Metallosphaera sedula 2 Cluster1 metacyc::MONOMER-13740 A4YEH9 acetyl-CoA C-acetyltransferase (EC 2.3.1.16) Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) 3 Cluster1 BRENDA::P42765 acetyl-CoA C-acyltransferase (EC 2.3.1.16) Homo sapiens 3 Cluster1 SwissProt::P42765 THIM_HUMAN 3-ketoacyl-CoA thiolase, mitochondrial; Acetyl-CoA acetyltransferase; Acetyl-CoA acyltransferase; Acyl-CoA hydrolase, mitochondrial; Beta-ketothiolase; Mitochondrial 3-oxoacyl-CoA thiolase; T1; EC 2.3.1.16; EC 2.3.1.9; EC 3.1.2.-; EC 3.1.2.1; EC 3.1.2.2 Homo sapiens (Human) 3 Cluster1 metacyc::HS09539-MONOMER P42765 3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) Homo sapiens 4 Cluster1 BRENDA::P45359 acetyl-CoA C-acetyltransferase (EC 2.3.1.9) Clostridium acetobutylicum 4 Cluster1 metacyc::THLCLOS-MONOMER P45359 acetoacetyl-CoA thiolase monomer (EC 2.3.1.16) Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) 5 Cluster1 BRENDA::Q22100 acetyl-CoA C-acyltransferase (EC 2.3.1.16) Caenorhabditis elegans 5 Cluster1 SwissProt::Q22100 THILH_CAEEL Acetyl-CoA acetyltransferase homolog, mitochondrial; 3-ketoacyl-CoA thiolase; EC 2.3.1.- Caenorhabditis elegans 6 Cluster1 BRENDA::Q56WD9 acetyl-CoA C-acyltransferase (EC 2.3.1.16) Arabidopsis thaliana 6 Cluster1 SwissProt::Q56WD9 THIK2_ARATH 3-ketoacyl-CoA thiolase 2, peroxisomal; Acetyl-CoA acyltransferase 2; Beta-ketothiolase 2; Peroxisomal 3-oxoacyl-CoA thiolase 2; Peroxisome defective protein 1; EC 2.3.1.16 Arabidopsis thaliana (Mouse-ear cress) 6 Cluster1 metacyc::AT2G33150-MONOMER Q56WD9 3-ketoacyl-CoA thiolase 2, peroxisomal (EC 2.3.1.16) Arabidopsis thaliana 7 Cluster1 BRENDA::Q6W6X6 acetyl-CoA C-acyltransferase (EC 2.3.1.16) Helianthus annuus 8 Cluster1 BRENDA::Q8VCH0 acetyl-CoA C-acyltransferase (EC 2.3.1.16) Mus musculus 8 Cluster1 SwissProt::Q8VCH0 THIKB_MOUSE 3-ketoacyl-CoA thiolase B, peroxisomal; Acetyl-CoA acyltransferase B; Beta-ketothiolase B; Peroxisomal 3-oxoacyl-CoA thiolase B; EC 2.3.1.155; EC 2.3.1.16; EC 2.3.1.9 Mus musculus (Mouse) 9 Cluster1 BRENDA::Q921H8 acetyl-CoA C-acyltransferase (EC 2.3.1.16) Mus musculus 9 Cluster1 SwissProt::Q921H8 THIKA_MOUSE 3-ketoacyl-CoA thiolase A, peroxisomal; Acetyl-CoA acyltransferase A; Beta-ketothiolase A; Peroxisomal 3-oxoacyl-CoA thiolase A; EC 2.3.1.16 Mus musculus (Mouse) 10 Cluster1 CharProtDB::CH_122169 3-ketoacyl-CoA ketothiolase (Kat1), putative (from HMM only) Emericella nidulans 11 Cluster1 CharProtDB::CH_123484 protein similar to acetyl-CoA acetyltransferase (from HMM only) Candida albicans 12 Cluster1 SwissProt::I6XHI4 FADA5_MYCTU Steroid 3-ketoacyl-CoA thiolase; Acetyl-CoA acetyltransferase FadA5; Beta-ketoacyl-CoA thiolase; EC 2.3.1.16 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 12 Cluster1 metacyc::G185E-7823-MONOMER I6XHI4 steroid 3-ketoacyl-CoA thiolase monomer (EC 2.3.1.16; EC 2.3.1.176) Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 13 Cluster1 SwissProt::O07618 YHFS_BACSU Putative acetyl-CoA C-acetyltransferase YhfS; EC 2.3.1.- (from HMM only) Bacillus subtilis (strain 168) 14 Cluster1 SwissProt::O32177 FADA_BACSU 3-ketoacyl-CoA thiolase; Acetyl-CoA acyltransferase; Beta-ketothiolase; EC 2.3.1.16 Bacillus subtilis (strain 168) 15 Cluster1 SwissProt::O53871 Y0859_MYCTU Putative acyltransferase Rv0859; EC 2.3.1.- (from HMM only) Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 16 Cluster1 SwissProt::P07871 THIKB_RAT 3-ketoacyl-CoA thiolase B, peroxisomal; Acetyl-CoA acyltransferase B; Beta-ketothiolase B; Peroxisomal 3-oxoacyl-CoA thiolase B; EC 2.3.1.155; EC 2.3.1.16; EC 2.3.1.9 Rattus norvegicus (Rat) 17 Cluster1 SwissProt::P09110 THIK_HUMAN 3-ketoacyl-CoA thiolase, peroxisomal; Acetyl-CoA acyltransferase; Beta-ketothiolase; Peroxisomal 3-oxoacyl-CoA thiolase; EC 2.3.1.16 Homo sapiens (Human) 17 Cluster1 metacyc::HS00752-MONOMER P09110 3-ketoacyl-CoA thiolase, peroxisomal (EC 2.3.1.223; EC 2.3.1.16) Homo sapiens 18 Cluster1 SwissProt::P0C7L2 PAAJ_ECOLI 3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase; EC 2.3.1.174; EC 2.3.1.223 Escherichia coli (strain K12) 18 Cluster1 ecocyc::G6718-MONOMER b1397 β-ketoadipyl-CoA thiolase (EC 2.3.1.223; EC 2.3.1.174) Escherichia coli K-12 substr. MG1655 18 Cluster1 metacyc::G6718-MONOMER P0C7L2 β-ketoadipyl-CoA thiolase (EC 2.3.1.223; EC 2.3.1.174) (from HMM only) Escherichia coli (strain K12) 19 Cluster1 SwissProt::P13437 THIM_RAT 3-ketoacyl-CoA thiolase, mitochondrial; Acetyl-CoA acetyltransferase; Acetyl-CoA acyltransferase; Acyl-CoA hydrolase, mitochondrial; Beta-ketothiolase; Mitochondrial 3-oxoacyl-CoA thiolase; EC 2.3.1.16; EC 2.3.1.9; EC 3.1.2.-; EC 3.1.2.1; EC 3.1.2.2 Rattus norvegicus (Rat) 20 Cluster1 SwissProt::P14611 THIL_CUPNH Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Beta-ketothiolase; EC 2.3.1.9 Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha) 20 Cluster1 metacyc::MONOMER-13086 P14611 acetyl-CoA acetyltransferase subunit (EC 2.3.1.16) Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) 21 Cluster1 SwissProt::P21151 FADA_ECOLI 3-ketoacyl-CoA thiolase FadA; Acetyl-CoA acyltransferase; Beta-ketothiolase; Fatty acid oxidation complex subunit beta; EC 2.3.1.16 Escherichia coli (strain K12) Heterotetramer of two alpha chains (FadB) and two beta chains (FadA) 21 Cluster1 ecocyc::FADA-MONOMER b3845 3-ketoacyl-CoA thiolase (EC 2.3.1.16) Escherichia coli K-12 substr. MG1655 Heterotetramer of two alpha chains (FadB) and two beta chains (FadA) 21 Cluster1 metacyc::FADA-MONOMER P21151 3-ketoacyl-CoA thiolase (EC 2.3.1.16) Escherichia coli (strain K12) Heterotetramer of two alpha chains (FadB) and two beta chains (FadA) 22 Cluster1 SwissProt::P24752 THIL_HUMAN Acetyl-CoA acetyltransferase, mitochondrial; Acetoacetyl-CoA thiolase; T2; EC 2.3.1.9 Homo sapiens (Human) 22 Cluster1 metacyc::HS01167-MONOMER P24752 acetyl-CoA acetyltransferase monomer (EC 2.3.1.16) Homo sapiens 23 Cluster1 SwissProt::P27796 THIK_YEAST 3-ketoacyl-CoA thiolase, peroxisomal; Acetyl-CoA acyltransferase; Beta-ketothiolase; Peroxisomal 3-oxoacyl-CoA thiolase; EC 2.3.1.16 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 24 Cluster1 SwissProt::P41338 THIL_YEAST Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Ergosterol biosynthesis protein 10; EC 2.3.1.9 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 24 Cluster1 metacyc::YPL028W-MONOMER P41338 Erg10 (EC 2.3.1.16) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 25 Cluster1 SwissProt::P55084 ECHB_HUMAN Trifunctional enzyme subunit beta, mitochondrial; TP-beta; EC 2.3.1.155; EC 2.3.1.16 Homo sapiens (Human) Heterotetramer of 2 alpha/HADHA and 2 beta/HADHB subunits; forms the mitochondrial trifunctional enzyme (PubMed:29915090, PubMed:30850536) 26 Cluster1 SwissProt::P76503 FADI_ECOLI 3-ketoacyl-CoA thiolase FadI; ACSs; Acetyl-CoA acyltransferase; Acyl-CoA ligase; Beta-ketothiolase; Fatty acid oxidation complex subunit beta; EC 2.3.1.16 Escherichia coli (strain K12) Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI) 26 Cluster1 ecocyc::G7213-MONOMER b2342 3-ketoacyl-CoA thiolase FadI (EC 2.3.1.16) Escherichia coli K-12 substr. MG1655 Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI) 26 Cluster1 metacyc::G7213-MONOMER P76503 3-ketoacyl-CoA thiolase FadI (EC 2.3.1.16) Escherichia coli (strain K12) Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI) 27 Cluster1 SwissProt::Q0KBP1 BKTB_CUPNH Beta-ketothiolase BktB; Acetyl-CoA acetyltransferase; Acetyl-CoA acyltransferase; EC 2.3.1.16; EC 2.3.1.9 Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha) 27 Cluster1 metacyc::MONOMER-16779 Q0KBP1 β-ketothiolase (EC 2.3.1.16) Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) 28 Cluster1 SwissProt::Q570C8 THIK5_ARATH 3-ketoacyl-CoA thiolase 5, peroxisomal; Acetyl-CoA acyltransferase 5; Beta-ketothiolase 5; Peroxisomal 3-oxoacyl-CoA thiolase 5; EC 2.3.1.16 Arabidopsis thaliana (Mouse-ear cress) 29 Cluster1 SwissProt::Q60587 ECHB_RAT Trifunctional enzyme subunit beta, mitochondrial; TP-beta; EC 2.3.1.155; EC 2.3.1.16 Rattus norvegicus (Rat) Heterotetramer of 2 alpha/HADHA and 2 beta/HADHB subunits; forms the mitochondrial trifunctional enzyme (By similarity) 30 Cluster1 SwissProt::Q8LF48 THIK1_ARATH 3-ketoacyl-CoA thiolase 1, peroxisomal; Acetyl-CoA acyltransferase 1; Beta-ketothiolase 1; Peroxisomal 3-oxoacyl-CoA thiolase 1; EC 2.3.1.16 Arabidopsis thaliana (Mouse-ear cress) 31 Cluster1 SwissProt::Q8SVA6 THIK_ENCCU 3-ketoacyl-CoA thiolase, peroxisomal; Acetyl-CoA acyltransferase; Beta-ketothiolase; Peroxisomal 3-oxoacyl-CoA thiolase; EC 2.3.1.16 Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite) 32 Cluster1 SwissProt::Q8VPF1 PCAF_PSEKB Beta-ketoadipyl-CoA thiolase; 3-oxoadipyl-CoA thiolase; EC 2.3.1.174 (from HMM only) Pseudomonas knackmussii (strain DSM 6978 / LMG 23759 / B13) 33 Cluster1 SwissProt::Q9BWD1 THIC_HUMAN Acetyl-CoA acetyltransferase, cytosolic; Acetyl-CoA transferase-like protein; Cytosolic acetoacetyl-CoA thiolase; EC 2.3.1.9 Homo sapiens (Human) 33 Cluster1 metacyc::ENSG00000120437-MONOMER Q9BWD1 acetyl-CoA acetyltransferase (EC 2.3.1.16) Homo sapiens 34 Cluster1 ecocyc::ACETYL-COA-ACETYLTRANSFER-MONOMER b2224 acetyl-CoA acetyltransferase (EC 2.3.1.16; EC 2.3.1.9) Escherichia coli K-12 substr. MG1655 34 Cluster1 metacyc::ACETYL-COA-ACETYLTRANSFER-MONOMER P76461 acetyl-CoA acetyltransferase (EC 2.3.1.16) Escherichia coli (strain K12) 35 Cluster1 metacyc::G185E-7833-MONOMER I6XHJ3 3-oxo-acyl CoA thiolase (EC 2.3.1.16) Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 36 Cluster1 metacyc::G1G01-2278-MONOMER Q88L01 FadA (EC 2.3.1.16) Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440) 37 Cluster1 metacyc::MONOMER-13468 A5N3I5 acetyl-CoA acetyltransferase (EC 2.3.1.16) Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680) 38 Cluster1 metacyc::MONOMER-13585 Q3IZW1 acetyl-CoA acetyltransferase (EC 2.3.1.16) Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158) 39 Cluster1 metacyc::MONOMER-14366 Q5P5K2 3-keto-acyl-CoA-thiolase (from HMM only) Aromatoleum aromaticum (strain EbN1) 40 Cluster1 metacyc::MONOMER-15952 Q845J8 β-ketoadipyl-CoA thiolase (EC 2.3.1.174; EC 2.3.1.223) (from HMM only) Pseudomonas sp. Y2 41 Cluster1 metacyc::MONOMER-17590 Q9HZJ3 fatty acid oxidation complex β subunit (EC 2.3.1.16) Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 42 Cluster1 metacyc::MONOMER-19852 A2SL81 acetyl-CoA C-acetyltransferase (EC 2.3.1.16) Methylibium petroleiphilum (strain ATCC BAA-1232 / LMG 22953 / PM1) 43 Cluster1 metacyc::MONOMER-20679 Q6N3H9 3-oxopimeloyl-CoA:CoA acetyltransferase (from HMM only) Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) 44 Cluster1 metacyc::MONOMER-20831 A0A1N7U0F8 acetyl-CoA C-acetyltransferase (EC 2.3.1.16) Pseudomonas simiae 45 Cluster1 metacyc::MONOMER-3207 Q51956 subunit of β-ketoadipyl CoA thiolase (EC 2.3.1.174; EC 2.3.1.16) Pseudomonas putida 46 Cluster1 reanno::ANA3:7022768 Shewana3_0023 Acetyl-CoA C-acyltransferase (EC 2.3.1.16) Shewanella sp. ANA-3 47 Cluster1 reanno::Koxy:BWI76_RS23710 BWI76_RS23710 3-keto-2-deoxy-D-ribonyl-CoA thiolase (from HMM only) Klebsiella michiganensis M5al 48 Cluster1 reanno::MR1:200842 SO1677 3-ketoacyl-CoA thiolase [isoleucine degradation] (EC 2.3.1.16) Shewanella oneidensis MR-1 49 Cluster1 reanno::Marino:GFF1551 HP15_1513 Acetyl-CoA C-acyltransferase (EC 2.3.1.16) Marinobacter adhaerens HP15 50 Cluster1 reanno::Marino:GFF2751 HP15_2695 Beta-ketoadipyl CoA thiolase (EC 2.3.1.-) (from HMM only) Marinobacter adhaerens HP15 51 Cluster1 reanno::Phaeo:GFF329 PGA1_c03400 acetyl-CoA:acetyl-CoA C-acetyltransferase / acetyl-CoA:propanoyl-CoA 2-C-acetyltransferase (EC 2.3.1.9; EC 2.3.1.16) Phaeobacter inhibens BS107 52 Cluster1 reanno::SB2B:6935813 Sama_0031 Acetyl-CoA C-acyltransferase (EC 2.3.1.16) Shewanella amazonensis SB2B 53 Cluster1 reanno::acidovorax_3H11:Ac3H11_2994 Ac3H11_2994 3-ketoacyl-CoA thiolase (EC 2.3.1.16) Acidovorax sp. GW101-3H11 54 Cluster1 reanno::pseudo13_GW456_L13:PfGW456L13_2982 PfGW456L13_2982 3-ketoacyl-CoA thiolase (EC 2.3.1.16) Pseudomonas fluorescens GW456-L13 55 Cluster1 reanno::pseudo3_N2E3:AO353_25685 AO353_25685 acetyl-CoA:acetyl-CoA C-acetyltransferase / acetyl-CoA:propanoyl-CoA 2-C-acetyltransferase (EC 2.3.1.9; EC 2.3.1.16) Pseudomonas fluorescens FW300-N2E3 56 Cluster2 BRENDA::P22307 propanoyl-CoA C-acyltransferase (EC 2.3.1.176) Homo sapiens 56 Cluster2 SwissProt::P22307 NLTP_HUMAN Non-specific lipid-transfer protein; NSL-TP; Propanoyl-CoA C-acyltransferase; SCP-chi; SCPX; Sterol carrier protein 2; SCP-2; Sterol carrier protein X; SCP-X; EC 2.3.1.176 Homo sapiens (Human) 56 Cluster2 metacyc::HS03991-MONOMER P22307 Non-specific lipid-transfer protein (EC 2.3.1.16) Homo sapiens 57 Cluster2 BRENDA::Q66Q58 acetyl-CoA C-acyltransferase (EC 2.3.1.16) Spodoptera littoralis 58 Singleton1 BRENDA::B8YJJ0 acetyl-CoA C-acyltransferase (EC 2.3.1.16) Lobosphaera incisa 59 Singleton2 BRENDA::Q64428 long-chain-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211); acetyl-CoA C-acyltransferase (EC 2.3.1.16) Rattus norvegicus Heterotetramer of 2 alpha/HADHA and 2 beta/HADHB subunits; forms the mitochondrial trifunctional enzyme (By similarity) 59 Singleton2 SwissProt::Q64428 ECHA_RAT Trifunctional enzyme subunit alpha, mitochondrial; Monolysocardiolipin acyltransferase; TP-alpha; EC 2.3.1.-; EC 4.2.1.17; EC 1.1.1.211 Rattus norvegicus (Rat) Heterotetramer of 2 alpha/HADHA and 2 beta/HADHB subunits; forms the mitochondrial trifunctional enzyme (By similarity) 60 Singleton3 BRENDA::Q9H5J4 acetyl-CoA C-acyltransferase (EC 2.3.1.16); very-long-chain 3-oxoacyl-CoA synthase (EC 2.3.1.199) Homo sapiens 60 Singleton3 SwissProt::Q9H5J4 ELOV6_HUMAN Elongation of very long chain fatty acids protein 6; 3-keto acyl-CoA synthase ELOVL6; ELOVL fatty acid elongase 6; ELOVL FA elongase 6; Fatty acid elongase 2; hELO2; Fatty acyl-CoA elongase; Long-chain fatty-acyl elongase; Very long chain 3-ketoacyl-CoA synthase 6; Very long chain 3-oxoacyl-CoA synthase 6; EC 2.3.1.199 Homo sapiens (Human) 60 Singleton3 metacyc::HS10142-MONOMER Q9H5J4 long chain fatty acid elongase 6 (EC 2.3.1.199) Homo sapiens 61 Singleton4 metacyc::MONOMER-14375 Q5P8S8 3-oxoacyl CoA thiolase (EC 2.3.1.16) Aromatoleum aromaticum (strain EbN1) 62 Singleton5 metacyc::MONOMER-18244 Q9FD70 acetyl-CoA acetyltransferase/HMG-CoA reductase (EC 1.1.1.34; EC 2.3.1.16) Enterococcus faecalis