Other Characterized Proteins Similar to hpcD

GapMind for catabolism of small carbon sources

Other Characterized Proteins Similar to hpcD

Finding the characterized proteins for hpcD (3-hydroxypropionyl-CoA dehydratase) in L-isoleucine catabolism

Or see clustering for step hpcD

Or see all steps for L-isoleucine catabolism

Or cluster curated proteins matching a keyword

Definition of hpcD

Curated proteins or TIGRFams with EC 4.2.1.116

Fetched 3 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 25 other characterized sequences. (Found 28 hits including self hits.)

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for hpcD.)

FOX2_CANTR / P22414 Peroxisomal hydratase-dehydrogenase-epimerase; HDE; Multifunctional beta-oxidation protein; MFP; EC 4.2.1.119; EC 1.1.1.n12 from Candida tropicalis (Yeast)
P22414 enoyl-CoA hydratase 2 (EC 4.2.1.119) from Candida tropicalis
PFams: adh_short, KR, adh_short_C2, adh_short, KR, adh_short_C2, MaoC_dehydratas
906 amino acids: PaperBLAST, CDD, BRENDA::P22414
90% identical to

A0A1D8PJ13 D-specific enoyl-CoA hydratase (EC 4.2.1.119; EC 4.2.1.116) from Candida albicans (strain SC5314 / ATCC MYA-2876)
PFams: adh_short, KR, adh_short_C2, adh_short, KR, adh_short_C2, MaoC_dehydratas
906 amino acids: PaperBLAST, CDD

A5N5C7 crotonase (EC 4.2.1.150) from Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680)
PFams: ECH_1, ECH_2
259 amino acids: PaperBLAST, CDD, metacyc::MONOMER-13469
49% identical to

A4YI89 3-hydroxypropionyl-CoA dehydratase (EC 4.2.1.116) from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)
HPCD_METS5 / A4YI89 3-hydroxypropionyl-coenzyme A dehydratase; 3-hydroxypropionyl-CoA dehydratase; EC 4.2.1.116 from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)
A4YI89 3-hydroxypropionyl-CoA dehydratase (EC 4.2.1.116) from Metallosphaera sedula
PFams: ECH_1, ECH_2
259 amino acids: PaperBLAST, CDD

ECHM_RAT / P14604 Enoyl-CoA hydratase, mitochondrial; Enoyl-CoA hydratase 1; Short-chain enoyl-CoA hydratase; SCEH; EC 4.2.1.17 from Rattus norvegicus (Rat)
P14604 enoyl-CoA hydratase (EC 4.2.1.17); DELTA3,5-DELTA2,4-dienoyl-CoA isomerase (EC 5.3.3.21) from Rattus norvegicus
PFams: ECH_1, ECH_2
290 amino acids: PaperBLAST, CDD, BRENDA::P14604
47% identical to

Psest_2437 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) from Pseudomonas stutzeri RCH2
PFams: ECH_1, ECH_2
257 amino acids: PaperBLAST, CDD, reanno::psRCH2:GFF2389
46% identical to

A4YDS4 crotonyl-CoA hydratase/(S)-3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.35; EC 4.2.1.150) from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)
A4YDS4 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35); short-chain-enoyl-CoA hydratase (EC 4.2.1.150) from Metallosphaera sedula
PFams: 3HCDH_N, NAD_binding_2, 3HCDH, 3HCDH, ECH_1, ECH_2
651 amino acids: PaperBLAST, CDD, BRENDA::A4YDS4
46% identical to

Q58DM8 short chain enoyl-CoA hydratase subunit (EC 4.2.1.17) from Bos taurus
PFams: ECH_1, ECH_2
290 amino acids: PaperBLAST, CDD, metacyc::MONOMER-11697
46% identical to

CH_122238 peroxisomal multifunctional beta-oxidation protein from Emericella nidulans
PFams: adh_short, KR, adh_short_C2, adh_short, adh_short_C2, KR, MaoC_dehydratas
883 amino acids: PaperBLAST, CDD, CharProtDB::CH_122238
46% identical to

CH_124256 multifunctional beta-oxidation protein (Peroxisomal hydratase-dehydrogenase-epimerase); EC 4.2.1.-, 1.1.1.- from Magnaporthe grisea 70-15
PFams: adh_short, KR, adh_short_C2, adh_short, KR, adh_short_C2, MaoC_dehydratas
896 amino acids: PaperBLAST, CDD, CharProtDB::CH_124256
45% identical to

P30084 mitochondrial enoyl-CoA hydratase (EC 4.2.1.17) from Homo sapiens
ECHM_HUMAN / P30084 Enoyl-CoA hydratase, mitochondrial; Enoyl-CoA hydratase 1; Short-chain enoyl-CoA hydratase; SCEH; EC 4.2.1.17 from Homo sapiens (Human)
P30084 enoyl-CoA hydratase (EC 4.2.1.17) from Homo sapiens
PFams: ECH_1, ECH_2
290 amino acids: PaperBLAST, CDD, BRENDA::P30084
45% identical to

FADB_BACSU / P94549 Probable enoyl-CoA hydratase; EC 4.2.1.17 from Bacillus subtilis (strain 168)
PFams: ECH_1, ECH_2
258 amino acids: PaperBLAST, CDD, SwissProt::P94549
46% identical to

CRCH_SYNWW / Q0AVM1 Crotonyl-CoA hydratase; EC 4.2.1.150 from Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen)
PFams: ECH_1, ECH_2
260 amino acids: PaperBLAST, CDD, SwissProt::Q0AVM1
43% identical to

P52046 crotonase monomer (EC 4.2.1.150) from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
CRT_CLOAB / P52046 Short-chain-enoyl-CoA hydratase; 3-hydroxybutyryl-CoA dehydratase; Crotonase; EC 4.2.1.150 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
CH_091794 3-hydroxybutyryl-CoA dehydratase; EC 4.2.1.55 from Clostridium acetobutylicum
PFams: ECH_1, ECH_2
261 amino acids: PaperBLAST, CDD, CharProtDB::CH_091794
42% identical to

O07453 BadK from Rhodopseudomonas palustris
PFams: ECH_1, ECH_2
258 amino acids: PaperBLAST, CDD, metacyc::MONOMER-943
42% identical to

BPHYT_RS17335 trans-2,3-dehydroadipyl-CoA hydratase (EC 4.2.1.17) from Burkholderia phytofirmans PsJN
PFams: ECH_1, ECH_2
258 amino acids: PaperBLAST, CDD, reanno::BFirm:BPHYT_RS17335
42% identical to

D3RXI4 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35); 3-hydroxybutyryl-CoA dehydratase (EC 4.2.1.55) from Ferroglobus placidus
PFams: 3HCDH_N, NAD_Gly3P_dh_N, NAD_binding_2, F420_oxidored, 3HCDH, 3HCDH, ECH_1, ECH_2
658 amino acids: PaperBLAST, CDD, BRENDA::D3RXI4
42% identical to

Q845K2 2,3-dehydroadipyl-CoA hydratase (EC 4.2.1.17) from Pseudomonas sp. Y2
PFams: ECH_1, ECH_2
257 amino acids: PaperBLAST, CDD, metacyc::MONOMER-15953
42% identical to

PAAF_ECOLI / P76082 2,3-dehydroadipyl-CoA hydratase; Enoyl-CoA hydratase; EC 4.2.1.17 from Escherichia coli (strain K12)
P76082 enoyl-CoA hydratase (EC 4.2.1.17) from Escherichia coli
PFams: ECH_1, ECH_2
255 amino acids: PaperBLAST, CDD, BRENDA::P76082
41% identical to

C8YX87 AcuK from Halomonas sp. HTNK1
PFams: ECH_1, ECH_2
253 amino acids: PaperBLAST, CDD, metacyc::MONOMER-15200
41% identical to

CH_121974 mitochondrial enoyl-CoA hydratase from Emericella nidulans
PFams: ECH_1, ECH_2
289 amino acids: PaperBLAST, CDD, CharProtDB::CH_121974
41% identical to

Q1D5Y4 methylglutaconyl-CoA hydratase (EC 4.2.1.18) from Myxococcus xanthus
PFams: ECH_2, ECH_1
258 amino acids: PaperBLAST, CDD, BRENDA::Q1D5Y4
42% identical to

Q9KJE7 putative phenylitaconyl-CoA hydratase subunit from Thauera aromatica
PFams: ECH_1, ECH_2
256 amino acids: PaperBLAST, CDD, metacyc::MONOMER-688
40% identical to

AUHM_MOUSE / Q9JLZ3 Methylglutaconyl-CoA hydratase, mitochondrial; AU-specific RNA-binding enoyl-CoA hydratase; AU-binding enoyl-CoA hydratase; muAUH; Itaconyl-CoA hydratase; EC 4.2.1.18; EC 4.2.1.56 from Mus musculus (Mouse)
PFams: ECH_1, ECH_2
314 amino acids: PaperBLAST, CDD, SwissProt::Q9JLZ3
40% identical to

b2341 3-hydroxyacyl-CoA dehydrogenase FadJ (EC 1.1.1.35; EC 1.1.1.211; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8) from Escherichia coli K-12 substr. MG1655
P77399 3-hydroxyacyl-CoA dehydrogenase FadJ (EC 1.1.1.35; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8) from Escherichia coli (strain K12)
FADJ_ECOLI / P77399 Fatty acid oxidation complex subunit alpha; EC 4.2.1.17; EC 5.1.2.3; EC 1.1.1.35 from Escherichia coli (strain K12)
RF|NP_416843 fatty acid oxidation complex subunit alpha; EC 1.1.1.35; EC 4.2.1.17; EC 5.1.2.3 from Escherichia coli K12
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH, 3HCDH
Heteromeric, 714 amino acids: PaperBLAST, CDD, CharProtDB::CH_003230
40% identical to

MFPA_CUCSA / Q39659 Glyoxysomal fatty acid beta-oxidation multifunctional protein MFP-a; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8; EC 1.1.1.35 from Cucumis sativus (Cucumber)
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH
725 amino acids: PaperBLAST, CDD, SwissProt::Q39659
40% identical to

MFP2_ARATH / Q9ZPI5 Peroxisomal fatty acid beta-oxidation multifunctional protein MFP2; AtMPF2; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8; EC 1.1.1.35 from Arabidopsis thaliana (Mouse-ear cress)
Q9ZPI5 enoyl-CoA hydratase (EC 4.2.1.17) from Arabidopsis thaliana
PFams: ECH_1, ECH_2, 3HCDH_N, 3HCDH
725 amino acids: PaperBLAST, CDD, BRENDA::Q9ZPI5
41% identical to