GapMind for catabolism of small carbon sources

 

Other Characterized Proteins Similar to iolA

Finding the characterized proteins for iolA (malonate semialdehyde dehydrogenase (CoA-acylating)) in L-isoleucine catabolism

Or see clustering for step iolA

Or see all steps for L-isoleucine catabolism

Or cluster curated proteins matching a keyword

Definition of iolA

Fetched 11 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 12 other characterized sequences. (Found 23 hits including self hits.)

Removing ignored items reduces this to 0 close sequences.

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for iolA.)

BAUC_PSEAE / Q9I702 Putative 3-oxopropanoate dehydrogenase; EC 1.2.1.- from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
PFams: Aldedh
497 amino acids: PaperBLAST, CDD, SwissProt::Q9I702
91% identical to

A0A081YAY7 malonate-semialdehyde dehydrogenase (EC 1.2.1.15); malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18); methylmalonate-semialdehyde dehydrogenase (CoA-acylating) (EC 1.2.1.27) from Pseudomonas sp.
PFams: Aldedh
498 amino acids: PaperBLAST, CDD

G5CZI2 methylmalonate-semialdehyde dehydrogenase (CoA-acylating) (EC 1.2.1.27) from Oceanimonas doudoroffii
PFams: Aldedh
498 amino acids: PaperBLAST, CDD, BRENDA::G5CZI2
67% identical to

A0A081YAY7 malonate-semialdehyde dehydrogenase (EC 1.2.1.15); malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18); methylmalonate-semialdehyde dehydrogenase (CoA-acylating) (EC 1.2.1.27) from Pseudomonas sp.
PFams: Aldedh
498 amino acids: PaperBLAST, CDD

CCNA_01360 Methylmalonate-semialdehyde dehydrogenase [inositol] (EC 1.2.1.27) from Caulobacter crescentus NA1000
PFams: Aldedh, LuxC
500 amino acids: PaperBLAST, CDD, reanno::Caulo:CCNA_01360
63% identical to

SMc00781 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) from Sinorhizobium meliloti 1021
PFams: Aldedh
498 amino acids: PaperBLAST, CDD

Q6Z4E4 methylmalonate-semialdehyde dehydrogenase (CoA-acylating) (EC 1.2.1.27) from Oryza sativa
PFams: Aldedh
534 amino acids: PaperBLAST, CDD, BRENDA::Q6Z4E4
58% identical to

MMSA_RAT / Q02253 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; MMSDH; Malonate-semialdehyde dehydrogenase [acylating]; Aldehyde dehydrogenase family 6 member A1; EC 1.2.1.18; EC 1.2.1.27 from Rattus norvegicus (Rat)
PFams: Aldedh
535 amino acids: PaperBLAST, CDD

Q8VUC5 methylmalonate-semialdehyde dehydrogenase subunit (EC 1.2.1.27) from Burkholderia cepacia
PFams: Aldedh
508 amino acids: PaperBLAST, CDD, metacyc::MONOMER-13339
60% identical to

MMSA_RAT / Q02253 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; MMSDH; Malonate-semialdehyde dehydrogenase [acylating]; Aldehyde dehydrogenase family 6 member A1; EC 1.2.1.18; EC 1.2.1.27 from Rattus norvegicus (Rat)
PFams: Aldedh
535 amino acids: PaperBLAST, CDD

Psest_2436 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) from Pseudomonas stutzeri RCH2
PFams: Aldedh
503 amino acids: PaperBLAST, CDD, reanno::psRCH2:GFF2388
60% identical to

Q9EQ20 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) from Mus musculus
PFams: Aldedh
535 amino acids: PaperBLAST, CDD

BWI76_RS03070 Methylmalonate-semialdehyde dehydrogenase [inositol] (EC 1.2.1.27) from Klebsiella michiganensis M5al
PFams: Aldedh
501 amino acids: PaperBLAST, CDD, reanno::Koxy:BWI76_RS03070
55% identical to

AO356_23175 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) from Pseudomonas fluorescens FW300-N2C3
PFams: Aldedh
500 amino acids: PaperBLAST, CDD

PfGW456L13_5146 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) from Pseudomonas fluorescens GW456-L13
PFams: Aldedh
508 amino acids: PaperBLAST, CDD, reanno::pseudo13_GW456_L13:PfGW456L13_5146
58% identical to

MMSA_HUMAN / Q02252 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; MMSDH; Malonate-semialdehyde dehydrogenase [acylating]; Aldehyde dehydrogenase family 6 member A1; EC 1.2.1.18; EC 1.2.1.27 from Homo sapiens (Human)
Q02252 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18); methylmalonate-semialdehyde dehydrogenase (CoA-acylating) (EC 1.2.1.27) from Homo sapiens
PFams: Aldedh
535 amino acids: PaperBLAST, CDD

Pf1N1B4_1229 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) from Pseudomonas fluorescens FW300-N1B4
PFams: Aldedh
505 amino acids: PaperBLAST, CDD, reanno::pseudo1_N1B4:Pf1N1B4_1229
58% identical to

MMSA_HUMAN / Q02252 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; MMSDH; Malonate-semialdehyde dehydrogenase [acylating]; Aldehyde dehydrogenase family 6 member A1; EC 1.2.1.18; EC 1.2.1.27 from Homo sapiens (Human)
Q02252 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18); methylmalonate-semialdehyde dehydrogenase (CoA-acylating) (EC 1.2.1.27) from Homo sapiens
PFams: Aldedh
535 amino acids: PaperBLAST, CDD

AO353_05990 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) from Pseudomonas fluorescens FW300-N2E3
PFams: Aldedh
507 amino acids: PaperBLAST, CDD, reanno::pseudo3_N2E3:AO353_05990
58% identical to

MMSA_HUMAN / Q02252 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; MMSDH; Malonate-semialdehyde dehydrogenase [acylating]; Aldehyde dehydrogenase family 6 member A1; EC 1.2.1.18; EC 1.2.1.27 from Homo sapiens (Human)
Q02252 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18); methylmalonate-semialdehyde dehydrogenase (CoA-acylating) (EC 1.2.1.27) from Homo sapiens
PFams: Aldedh
535 amino acids: PaperBLAST, CDD

MMSA_PSEAE / P28810 Methylmalonate-semialdehyde dehydrogenase [acylating]; MMSDH; EC 1.2.1.27 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
P28810 methylmalonate-semialdehyde dehydrogenase subunit (EC 1.2.1.27) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
PFams: Aldedh
497 amino acids: PaperBLAST, CDD, SwissProt::P28810
49% identical to

A0A081YAY7 malonate-semialdehyde dehydrogenase (EC 1.2.1.15); malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18); methylmalonate-semialdehyde dehydrogenase (CoA-acylating) (EC 1.2.1.27) from Pseudomonas sp.
PFams: Aldedh
498 amino acids: PaperBLAST, CDD

Q97YT9 methylmalonate-semialdehyde dehydrogenase (CoA-acylating) (EC 1.2.1.27) from Saccharolobus solfataricus
PFams: Aldedh
492 amino acids: PaperBLAST, CDD, BRENDA::Q97YT9
47% identical to

IOLA_BACSU / P42412 Malonate-semialdehyde dehydrogenase; MSA dehydrogenase; Methylmalonate-semialdehyde dehydrogenase; MMSA dehydrogenase; MMSDH; MSDH; EC 1.2.1.-; EC 1.2.1.27 from Bacillus subtilis (strain 168)
P42412 methylmalonate-semialdehyde dehydrogenase (CoA-acylating) (EC 1.2.1.27) from Bacillus subtilis
P42412 (methyl)malonate-semialdehyde dehydrogenase monomer (EC 1.2.1.27; EC 1.2.1.18) from Bacillus subtilis (strain 168)
PFams: Aldedh
487 amino acids: PaperBLAST, CDD