GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for lpd (branched-chain alpha-ketoacid dehydrogenase, E3 component) in L-isoleucine catabolism

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Definition of lpd

Fetched 48 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 47 of these sequences

Found 1 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 411-623 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

Q8VPK7 dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Streptococcus pneumoniae
PFams: Biotin_lipoyl, HI0933_like, Pyr_redox_2, FAD_binding_2, FAD_oxidored, GIDA, Trp_halogenase, Pyr_redox_3, Pyr_redox, Pyr_redox_dim
567 amino acids: PaperBLAST, CDD, Compare to cluster

A0A0H2Z9F5 dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Pseudomonas aeruginosa
Q9I3D1 dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Pseudomonas aeruginosa
PFams: HI0933_like, Pyr_redox_2, FAD_binding_2, GIDA, Pyr_redox_3, 3HCDH_N, Pyr_redox, Pyr_redox_dim
478 amino acids: PaperBLAST, CDD, Compare to cluster

A0A0H2ZB32 dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Pseudomonas aeruginosa
PFams: Pyr_redox_2, GIDA, Pyr_redox, Pyr_redox_dim
464 amino acids: PaperBLAST, CDD, Compare to cluster

A0A0H2ZHZ0 dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Pseudomonas aeruginosa
PFams: Pyr_redox_2, FAD_binding_2, FAD_oxidored, GIDA, Pyr_redox, Pyr_redox_dim
467 amino acids: PaperBLAST, CDD, Compare to cluster

A0A0K9R8G5 dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Spinacia oleracea
PFams: Pyr_redox_2, GIDA, Pyr_redox, Pyr_redox_dim
565 amino acids: PaperBLAST, CDD, Compare to cluster

A4V929 dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Acidianus ambivalens
PFams: HI0933_like, Pyr_redox_2, FAD_oxidored, NAD_binding_8, Pyr_redox, Pyr_redox_dim
411 amino acids: PaperBLAST, CDD, Compare to cluster

A5N930 dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Clostridium kluyveri
PFams: Pyr_redox_2, FAD_binding_2, FAD_oxidored, GIDA, Pyr_redox_3, Pyr_redox, Pyr_redox_dim
455 amino acids: PaperBLAST, CDD, Compare to cluster

B6F1A8 dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Microbacterium luteolum
PFams: Pyr_redox_2, FAD_oxidored, GIDA, Pyr_redox_3, Pyr_redox, 3HCDH_N, Pyr_redox_dim
465 amino acids: PaperBLAST, CDD, Compare to cluster

O81413 leghemoglobin reductase (EC 1.6.2.6) (from HMM only) from Glycine max
PFams: FAD_binding_2, FAD_oxidored, GIDA, Pyr_redox_2, Pyr_redox_3, NAD_binding_8, Pyr_redox, Pyr_redox_dim
500 amino acids: PaperBLAST, CDD, Compare to cluster

DLDH_HUMAN / P09622 Dihydrolipoyl dehydrogenase, mitochondrial; Dihydrolipoamide dehydrogenase; Glycine cleavage system L protein; EC 1.8.1.4 from Homo sapiens (Human)
P09622 dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Homo sapiens
P09622 dihydrolipoyl dehydrogenase monomer (EC 1.8.1.4) from Homo sapiens
PFams: FAD_binding_2, FAD_oxidored, GIDA, Pyr_redox_2, NAD_binding_8, Pyr_redox, Pyr_redox_dim
509 amino acids: PaperBLAST, CDD, Compare to cluster

DLDH_PIG / P09623 Dihydrolipoyl dehydrogenase, mitochondrial; Dihydrolipoamide dehydrogenase; EC 1.8.1.4 from Sus scrofa (Pig)
P09623 dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Sus scrofa
PFams: FAD_binding_2, FAD_oxidored, GIDA, Pyr_redox_2, NAD_binding_8, Pyr_redox, Pyr_redox_dim
509 amino acids: PaperBLAST, CDD, Compare to cluster

b0116 lipoamide dehydrogenase (EC 1.8.1.4) from Escherichia coli K-12 substr. MG1655
DLDH_ECOLI / P0A9P0 Dihydrolipoyl dehydrogenase; Dihydrolipoamide dehydrogenase; E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes; Glycine cleavage system L protein; EC 1.8.1.4 from Escherichia coli (strain K12)
P0A9P0 dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Escherichia coli
P0A9P0 lipoamide dehydrogenase (EC 1.8.1.4) from Escherichia coli (strain K12)
SP|P0A9P1 dihydrolipoyl dehydrogenase; EC 1.8.1.4 from Escherichia coli K12
PFams: FAD_oxidored, GIDA, Pyr_redox_2, FAD_binding_2, Pyr_redox, Pyr_redox_dim
474 amino acids: PaperBLAST, CDD, Compare to cluster

P50970 dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Zymomonas mobilis
PFams: Pyr_redox_2, FAD_binding_2, FAD_oxidored, GIDA, Pyr_redox_3, Pyr_redox, Pyr_redox_dim
466 amino acids: PaperBLAST, CDD, Compare to cluster

DLDH_MYCTU / P9WHH9 Dihydrolipoyl dehydrogenase; LPD; Component of peroxynitrite reductase/peroxidase complex; Component of PNR/P; Dihydrolipoamide dehydrogenase; E3 component of alpha-ketoacid dehydrogenase complexes; EC 1.8.1.4 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WHH8 dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Mycobacterium tuberculosis
P9WHH9 dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Mycobacterium tuberculosis
PFams: Pyr_redox_2, FAD_binding_2, FAD_oxidored, GIDA, Pyr_redox, Pyr_redox_dim
464 amino acids: PaperBLAST, CDD, Compare to cluster

Q04829 dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Haloferax volcanii
PFams: FAD_binding_2, FAD_oxidored, GIDA, Pyr_redox_2, Pyr_redox_3, Pyr_redox, Pyr_redox_dim
475 amino acids: PaperBLAST, CDD, Compare to cluster

Q0KBV8 dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Cupriavidus necator
CH_010326 dihydrolipoyl dehydrogenase; EC 1.8.1.4 from Cupriavidus necator
PFams: Biotin_lipoyl, FAD_oxidored, GIDA, Pyr_redox_2, Pyr_redox, Pyr_redox_dim
594 amino acids: PaperBLAST, CDD, Compare to cluster

Q8MUB0 dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Bombyx mori
PFams: FAD_binding_2, FAD_oxidored, GIDA, Pyr_redox_2, Pyr_redox_3, Pyr_redox, Pyr_redox_dim
496 amino acids: PaperBLAST, CDD, Compare to cluster

DLDH2_ARATH / Q9M5K2 Dihydrolipoyl dehydrogenase 2, mitochondrial; AtmLPD2; mtLPD2; Dihydrolipoamide dehydrogenase 2; Glycine cleavage system L protein 2; Pyruvate dehydrogenase complex E3 subunit 2; E3-2; PDC-E3 2; EC 1.8.1.4 from Arabidopsis thaliana (Mouse-ear cress)
Q9M5K2 dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Arabidopsis thaliana
PFams: FAD_binding_2, FAD_oxidored, GIDA, Pyr_redox_2, NAD_binding_8, Pyr_redox_3, Pyr_redox, Pyr_redox_dim
507 amino acids: PaperBLAST, CDD, Compare to cluster

P21880 dihydrolipoyl dehydrogenase component subunit (EC 1.8.1.4) from Bacillus subtilis (strain 168)
GB|CAB13334.1 dihydrolipoyl dehydrogenase; EC 1.8.1.4 from Bacillus subtilis
PFams: FAD_binding_2, Pyr_redox_2, GIDA, Pyr_redox_3, Pyr_redox, Pyr_redox_dim
470 amino acids: PaperBLAST, CDD, Compare to cluster

CH_006552 TPP-dependent acetoin dehydrogenase complex, E3 component, dihydrolipoyl dehydrogenase; EC 1.8.1.4 from Clostridium magnum
PFams: Biotin_lipoyl, Pyr_redox_2, FAD_binding_2, FAD_oxidored, GIDA, HI0933_like, Pyr_redox_3, NAD_binding_8, Pyr_redox, Pyr_redox_dim
578 amino acids: PaperBLAST, CDD, Compare to cluster

GI|1256717 dihydrolipoyl dehydrogenase; EC 1.8.1.4 from Pseudomonas putida
PFams: HI0933_like, Pyr_redox_2, FAD_binding_2, FAD_oxidored, GIDA, Pyr_redox_3, Pyr_redox, Pyr_redox_dim
478 amino acids: PaperBLAST, CDD, Compare to cluster

CH_123536 dihydrolipoyl dehydrogenase; EC 1.8.1.4 from Candida albicans
PFams: Pyr_redox_2, FAD_binding_2, FAD_oxidored, GIDA, Pyr_redox, Pyr_redox_dim
491 amino acids: PaperBLAST, CDD, Compare to cluster

RF|NP_593496.1 dihydrolipoamide dehydrogenase Dld1; EC 1.8.1.4 from Schizosaccharomyces pombe
PFams: Pyr_redox_2, FAD_binding_2, FAD_oxidored, GIDA, Pyr_redox, Pyr_redox_dim
511 amino acids: PaperBLAST, CDD, Compare to cluster

PLPD1_ARATH / A8MS68 Dihydrolipoyl dehydrogenase 1, chloroplastic; ptLPD1; Dihydrolipoamide dehydrogenase 1; Protein LIPOAMIDE DEHYDROGENASE 1; Pyruvate dehydrogenase complex E3 subunit 1; E3-1; PDC-E3 1; EC 1.8.1.4 from Arabidopsis thaliana (Mouse-ear cress)
PFams: Pyr_redox_2, GIDA, Pyr_redox, Pyr_redox_dim
623 amino acids: PaperBLAST, CDD, Compare to cluster

PLPD2_ARATH / F4JLP5 Dihydrolipoyl dehydrogenase 2, chloroplastic; ptLPD2; Dihydrolipoamide dehydrogenase 2; Protein LIPOAMIDE DEHYDROGENASE 2; Pyruvate dehydrogenase complex E3 subunit 2; E3-2; PDC-E3 2; EC 1.8.1.4 from Arabidopsis thaliana (Mouse-ear cress)
PFams: Pyr_redox_2, GIDA, Pyr_redox, Pyr_redox_dim
567 amino acids: PaperBLAST, CDD, Compare to cluster

DLDH_MOUSE / O08749 Dihydrolipoyl dehydrogenase, mitochondrial; Dihydrolipoamide dehydrogenase; EC 1.8.1.4 from Mus musculus (Mouse)
PFams: FAD_binding_2, FAD_oxidored, GIDA, Pyr_redox_2, NAD_binding_8, Pyr_redox, Pyr_redox_dim
509 amino acids: PaperBLAST, CDD, Compare to cluster

DLDH1_PSEPU / P09063 Dihydrolipoyl dehydrogenase; Dihydrolipoamide dehydrogenase; E3 component of branched-chain alpha-keto acid dehydrogenase complex; LPD-Val; EC 1.8.1.4 from Pseudomonas putida (Arthrobacter siderocapsulatus)
PFams: Pyr_redox_2, GIDA, Pyr_redox_3, Pyr_redox, Pyr_redox_dim
459 amino acids: PaperBLAST, CDD, Compare to cluster

DLDH_YEAST / P09624 Dihydrolipoyl dehydrogenase, mitochondrial; Dihydrolipoamide dehydrogenase; Glycine decarboxylase complex subunit L; Lipoamide dehydrogenase component of pyruvate dehydrogenase complex; Pyruvate dehydrogenase complex E3 component; EC 1.8.1.4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: HI0933_like, Pyr_redox_2, FAD_binding_2, FAD_oxidored, GIDA, NAD_binding_8, Pyr_redox, Pyr_redox_dim
499 amino acids: PaperBLAST, CDD, Compare to cluster

DLDH1_GEOSE / P11959 Dihydrolipoyl dehydrogenase; Dihydrolipoamide dehydrogenase; E3 component of pyruvate complex; EC 1.8.1.4 from Geobacillus stearothermophilus (Bacillus stearothermophilus)
P11959 dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Geobacillus stearothermophilus
GB|CAA37631.1 dihydrolipoyl dehydrogenase; EC 1.8.1.4 from Geobacillus stearothermophilus
PFams: FAD_binding_2, Pyr_redox_2, FAD_oxidored, GIDA, Pyr_redox_3, Pyr_redox, Pyr_redox_dim
470 amino acids: PaperBLAST, CDD, Compare to cluster

DLDH_PSEFL / P14218 Dihydrolipoyl dehydrogenase; Dihydrolipoamide dehydrogenase; E3 component of 2-oxoglutarate dehydrogenase complex; EC 1.8.1.4 from Pseudomonas fluorescens
PFams: HI0933_like, Pyr_redox_2, FAD_binding_2, GIDA, Pyr_redox_3, 3HCDH_N, Pyr_redox, Pyr_redox_dim
478 amino acids: PaperBLAST, CDD, Compare to cluster

DLDH_AZOVI / P18925 Dihydrolipoyl dehydrogenase; Dihydrolipoamide dehydrogenase; E3 component of pyruvate complex; EC 1.8.1.4 from Azotobacter vinelandii
GI|142325 dihydrolipoyl dehydrogenase; EC 1.8.1.4 from Azotobacter vinelandii
PFams: HI0933_like, Pyr_redox_2, FAD_binding_2, FAD_oxidored, GIDA, Pyr_redox_3, 3HCDH_N, Pyr_redox, Pyr_redox_dim
477 amino acids: PaperBLAST, CDD, Compare to cluster

DLDH_PEA / P31023 Dihydrolipoyl dehydrogenase, mitochondrial; Dihydrolipoamide dehydrogenase; Glycine cleavage system L protein; Pyruvate dehydrogenase complex E3 subunit; E3; PDC-E3; EC 1.8.1.4 from Pisum sativum (Garden pea)
PFams: FAD_binding_2, FAD_oxidored, GIDA, Pyr_redox_2, NAD_binding_8, Pyr_redox_3, Pyr_redox, Pyr_redox_dim
501 amino acids: PaperBLAST, CDD, Compare to cluster

DLDH_THESS / P85207 Dihydrolipoyl dehydrogenase; Dihydrolipoamide dehydrogenase; EC 1.8.1.4 from Thermus scotoductus (strain ATCC 700910 / SA-01)
PFams: Pyr_redox_2, GIDA, Pyr_redox_3, Pyr_redox, Pyr_redox_dim
461 amino acids: PaperBLAST, CDD, Compare to cluster

LEGRE_SOYBN / Q41219 Leghemoglobin reductase; Ferric leghemoglobin reductase; FLbR; EC 1.6.2.6 (from HMM only) from Glycine max (Soybean) (Glycine hispida)
PFams: FAD_binding_2, FAD_oxidored, GIDA, Pyr_redox_2, NAD_binding_8, Pyr_redox_3, Pyr_redox, UDPG_MGDP_dh_N, Pyr_redox_dim
523 amino acids: PaperBLAST, CDD, Compare to cluster

DLDH_MESAU / Q811C4 Dihydrolipoyl dehydrogenase, mitochondrial; Dihydrolipoamide dehydrogenase; EC 1.8.1.4 from Mesocricetus auratus (Golden hamster)
PFams: FAD_binding_2, FAD_oxidored, GIDA, Pyr_redox_2, NAD_binding_8, Pyr_redox, Pyr_redox_dim
479 amino acids: PaperBLAST, CDD, Compare to cluster

DLDH_CORGL / Q8NTE1 Dihydrolipoyl dehydrogenase; LPD; Dihydrolipoamide dehydrogenase; E3 component of alpha-ketoacid dehydrogenase complexes; EC 1.8.1.4 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
PFams: Pyr_redox_2, FAD_binding_2, FAD_oxidored, GIDA, Pyr_redox_3, Pyr_redox, Pyr_redox_dim
469 amino acids: PaperBLAST, CDD, Compare to cluster

DLDH1_ARATH / Q9M5K3 Dihydrolipoyl dehydrogenase 1, mitochondrial; AtmLPD1; mtLPD1; Dihydrolipoamide dehydrogenase 1; Glycine cleavage system L protein 1; Pyruvate dehydrogenase complex E3 subunit 1; E3-1; PDC-E3 1; EC 1.8.1.4 from Arabidopsis thaliana (Mouse-ear cress)
PFams: FAD_binding_2, FAD_oxidored, GIDA, Pyr_redox_2, NAD_binding_8, Pyr_redox_3, Pyr_redox, Pyr_redox_dim
507 amino acids: PaperBLAST, CDD, Compare to cluster

LEGRE_VIGUN / Q9SPB1 Leghemoglobin reductase; Ferric leghemoglobin reductase; FLbR; EC 1.6.2.6 (from HMM only) from Vigna unguiculata (Cowpea)
PFams: FAD_binding_2, FAD_oxidored, GIDA, Pyr_redox_2, NAD_binding_8, Pyr_redox_3, Pyr_redox, Pyr_redox_dim
523 amino acids: PaperBLAST, CDD, Compare to cluster

Q5ZM32 lipoamide dehydrogenase (EC 1.8.1.4) from Gallus gallus
PFams: FAD_binding_2, FAD_oxidored, GIDA, Pyr_redox_2, NAD_binding_8, Pyr_redox, Pyr_redox_dim
508 amino acids: PaperBLAST, CDD, Compare to cluster

Q9XLX6 dihydrolipoyl dehydrogenase subunit (EC 1.8.1.4) from Ascaris suum
PFams: FAD_binding_2, FAD_oxidored, GIDA, Pyr_redox_2, Pyr_redox_3, Pyr_redox, Pyr_redox_dim
498 amino acids: PaperBLAST, CDD, Compare to cluster

B3TZD6 dihydrolipoamide dehydrogenase (EC 1.8.1.4) from Advenella kashmirensis
PFams: Biotin_lipoyl, FAD_binding_2, FAD_oxidored, GIDA, Pyr_redox_2, Pyr_redox, Pyr_redox_dim
613 amino acids: PaperBLAST, CDD, Compare to cluster

P75393 pyruvate dehydrogenase complex E3 component (EC 1.8.1.4) from Mycoplasma pneumoniae (strain ATCC 29342 / M129)
PFams: Pyr_redox_2, FAD_binding_2, GIDA, Pyr_redox_3, K_oxygenase, Pyr_redox, Pyr_redox_dim
457 amino acids: PaperBLAST, CDD, Compare to cluster

SMc03204 Dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Sinorhizobium meliloti 1021
PFams: Pyr_redox_2, GIDA, Pyr_redox, Pyr_redox_dim
464 amino acids: PaperBLAST, CDD, Compare to cluster

PS417_17560 Dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Pseudomonas simiae WCS417
PFams: Pyr_redox_2, GIDA, Pyr_redox_3, Pyr_redox, Pyr_redox_dim
459 amino acids: PaperBLAST, CDD, Compare to cluster

PfGW456L13_3543 Dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Pseudomonas fluorescens GW456-L13
PFams: Pyr_redox_2, GIDA, Pyr_redox_3, Pyr_redox, Pyr_redox_dim
460 amino acids: PaperBLAST, CDD, Compare to cluster

AO356_22975 Dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Pseudomonas fluorescens FW300-N2C3
PFams: Pyr_redox_2, GIDA, Pyr_redox_3, Pyr_redox, Pyr_redox_dim
461 amino acids: PaperBLAST, CDD, Compare to cluster

Pf6N2E2_478 Dihydrolipoyl dehydrogenase (EC 1.8.1.4) from Pseudomonas fluorescens FW300-N2E2
PFams: Pyr_redox_2, GIDA, Pyr_redox_3, Pyr_redox, Pyr_redox_dim
461 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/1 heteromeric)

DLDH_HYMDI / P80647 Dihydrolipoyl dehydrogenase; Dihydrolipoamide dehydrogenase; EC 1.8.1.4 from Hymenolepis diminuta (Rat tapeworm)
PFams: Pyr_redox_2, FAD_binding_2, FAD_oxidored, GIDA
53 amino acids: PaperBLAST, CDD