Other Characterized Proteins Similar to ofoA

GapMind for catabolism of small carbon sources

Other Characterized Proteins Similar to ofoA

Finding the characterized proteins for ofoA (branched-chain alpha-ketoacid:ferredoxin oxidoreductase, alpha subunit OfoA) in L-isoleucine catabolism

Or see clustering for step ofoA

Or see all steps for L-isoleucine catabolism

Or cluster curated proteins matching a keyword

Definition of ofoA

Curated sequence P72578: 2-oxoacid:ferredoxin oxidoreductase subunit alpha; OFOR; EC 1.2.7.11. 2-oxoacid oxidoreductase (ferredoxin) (subunit 2/2) (EC 1.2.7.11). 2-oxoacid:ferredoxin oxidoreductase α subunit (EC 1.2.7.11; EC 1.2.7.1; EC 1.2.7.3; EC 1.2.7.7)
Ignore hits to items matching 1.2.7.7 when looking for 'other' hits
Ignore hits to items matching 1.2.7.11 when looking for 'other' hits
Comment: ofoAB is similar to low-specificity 2-oxoacid oxidoreductases (EC 1.2.7.11); it is generally not certain if these act on 4-methyl-2-oxopentanoate or not, but they probably do.

Fetched 1 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 5 other characterized sequences. (Found 6 hits including self hits.)

Removing ignored items reduces this to 0 close sequences.

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for ofoA.)

OFOA1_SULTO / Q96Y66 2-oxoacid:ferredoxin oxidoreductase 1, subunit alpha; OFOR1; EC 1.2.7.11 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii)
Q96Y66 2-oxoacid oxidoreductase (ferredoxin) (subunit 2/2) (EC 1.2.7.11) from Sulfurisphaera tokodaii
PFams: POR, POR_N
Heteromeric, 627 amino acids: PaperBLAST, CDD, SwissProt::Q96Y66
99% identical to

P72578 2-oxoacid:ferredoxin oxidoreductase α subunit (EC 1.2.7.11; EC 1.2.7.1; EC 1.2.7.3; EC 1.2.7.7) from Sulfolobus sp.
OFOA_SULSP / P72578 2-oxoacid:ferredoxin oxidoreductase subunit alpha; OFOR; EC 1.2.7.11 from Sulfolobus sp.
P72578 2-oxoacid oxidoreductase (ferredoxin) (subunit 2/2) (EC 1.2.7.11) from Sulfolobus sp.
PFams: POR, POR_N
Heteromeric, 632 amino acids: PaperBLAST, CDD

OFOA_SACSO / A0A0E3JT70 2-oxoacid:ferredoxin oxidoreductase subunit alpha; OFOR; EC 1.2.7.11 from Saccharolobus solfataricus (Sulfolobus solfataricus)
PFams: POR, POR_N, Transketolase_C, PFOR_II
Heteromeric, 632 amino acids: PaperBLAST, CDD, SwissProt::A0A0E3JT70
63% identical to

OFOA2_SULTO / Q96XT2 2-oxoacid:ferredoxin oxidoreductase 2, subunit alpha; OFOR2; EC 1.2.7.11 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii)
Q96XT2 2-oxoacid oxidoreductase (ferredoxin) (subunit 2/2) (EC 1.2.7.11) from Sulfurisphaera tokodaii
PFams: POR, POR_N, Transketolase_C, PFOR_II
Heteromeric, 628 amino acids: PaperBLAST, CDD, SwissProt::Q96XT2
59% identical to

OFOA1_AERPE / Q9YA13 2-oxoacid:ferredoxin oxidoreductase 1, subunit alpha; OFOR1; EC 1.2.7.11 from Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
PFams: POR, POR_N, PFOR_II
Heteromeric, 639 amino acids: PaperBLAST, CDD, SwissProt::Q9YA13
42% identical to

OFOA2_AERPE / Q9YBX7 2-oxoacid:ferredoxin oxidoreductase 2, subunit alpha; OFOR2; EC 1.2.7.11 from Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
PFams: POR, POR_N, Transketolase_C, PFOR_II
Heteromeric, 642 amino acids: PaperBLAST, CDD, SwissProt::Q9YBX7
40% identical to