Finding the characterized proteins for aacS (acetoacetyl-CoA synthetase) in L-leucine catabolism
Or see clustering for step aacS
Or see all steps for L-leucine catabolism
Or cluster curated proteins matching a keyword
Definition of aacS
Fetched 9 sequences
Running ublast to find other characterized proteins with 40% identity and 70% coverage
Found hits to 3 other characterized sequences. (Found 12 hits including self hits.)
There are also 2 HMM-only high-coverage hits.
(Sequences that are similar to these will not be high-confidence candidates for aacS.)
ACSF2_HUMAN / Q96CM8 Medium-chain acyl-CoA ligase ACSF2, mitochondrial; EC 6.2.1.2 from Homo sapiens (Human)
PFams: AMP-binding, AMP-binding_C
615 amino acids: PaperBLAST, CDD, SwissProt::Q96CM8
46% identical to
Ac3H11_3009 Acetoacetate--CoA ligase (EC 6.2.1.16) from Acidovorax sp. GW101-3H11
PFams: AMP-binding, AMP-binding_C
578 amino acids: PaperBLAST, CDD
SIDI_ASPFU / Q4WR83 Acyl-CoA ligase sidI; Siderophore biosynthesis protein I; EC 6.2.1.- from Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
PFams: AMP-binding, AMP-binding_C
590 amino acids: PaperBLAST, CDD, SwissProt::Q4WR83
41% identical to
Ac3H11_3009 Acetoacetate--CoA ligase (EC 6.2.1.16) from Acidovorax sp. GW101-3H11
PFams: AMP-binding, AMP-binding_C
578 amino acids: PaperBLAST, CDD
SID4_AJECA / B2KWI3 Acyl-CoA ligase SID4; Siderophore biosynthesis cluster protein SID4; EC 6.2.1.- from Ajellomyces capsulatus (Darling's disease fungus) (Histoplasma capsulatum)
PFams: AMP-binding, AMP-binding_C
589 amino acids: PaperBLAST, CDD, SwissProt::B2KWI3
42% identical to
Ac3H11_3009 Acetoacetate--CoA ligase (EC 6.2.1.16) from Acidovorax sp. GW101-3H11
PFams: AMP-binding, AMP-binding_C
578 amino acids: PaperBLAST, CDD
(Since these sequences' annotations are outside the definition for aacS, HMM hits that are over 40% similar to these sequences will be scored as moderate confidence.)
Q5P8R9 4-hydroxybenzoyl-acetyl-CoA synthetase from Aromatoleum aromaticum (strain EbN1)
PFams: ACAS_N, AMP-binding
664 amino acids: PaperBLAST, CDD
VRTB_PENAE / D7PHZ3 Malonamoyl-CoA synthetase vrtB; Viridicatumtoxin synthesis protein B; EC 6.2.1.- from Penicillium aethiopicum
PFams: ACAS_N, AMP-binding, AMP-binding_C
723 amino acids: PaperBLAST, CDD