GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for bkdC (branched-chain alpha-ketoacid dehydrogenase, E2 component) in L-leucine catabolism

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Definition of bkdC

Fetched 11 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 11 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 378-495 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

ODB2_HUMAN / P11182 Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial; 52 kDa mitochondrial autoantigen of primary biliary cirrhosis; Branched chain 2-oxo-acid dehydrogenase complex component E2; BCOADC-E2; Branched-chain alpha-keto acid dehydrogenase complex component E2; BCKAD-E2; BCKADE2; Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex; Dihydrolipoamide branched chain transacylase; Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase; EC 2.3.1.168 from Homo sapiens (Human)
P11182 dihydrolipoyllysine-residue (2-methylpropanoyl)transferase (EC 2.3.1.168) from Homo sapiens
P11182 branched-chain α-keto acid dehydrogenase complex E2 component subunit (EC 2.3.1.168) from Homo sapiens
PFams: Biotin_lipoyl, E3_binding, 2-oxoacid_dh
482 amino acids: PaperBLAST, CDD, Compare to cluster

Q8QHL7 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (EC 1.2.4.4); dihydrolipoyllysine-residue (2-methylpropanoyl)transferase (EC 2.3.1.168) from Oncorhynchus mykiss
PFams: Biotin_lipoyl, E3_binding, 2-oxoacid_dh
495 amino acids: PaperBLAST, CDD, Compare to cluster

Q98UJ6 dihydrolipoyllysine-residue (2-methylpropanoyl)transferase (EC 2.3.1.168) from Gallus gallus
PFams: Biotin_lipoyl, E3_binding, 2-oxoacid_dh
493 amino acids: PaperBLAST, CDD, Compare to cluster

BKDC_MYCTU / O06159 Dihydrolipoyllysine-residue acyltransferase component of branched-chain alpha-ketoacid dehydrogenase complex; Branched-chain alpha-ketoacid dehydrogenase complex component E2; BCKADH E2; Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase; EC 2.3.1.168 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PFams: Biotin_lipoyl, E3_binding, 2-oxoacid_dh
393 amino acids: PaperBLAST, CDD, Compare to cluster

ODB2_BOVIN / P11181 Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial; Branched-chain alpha-keto acid dehydrogenase complex component E2; BCKAD-E2; BCKADE2; Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex; Dihydrolipoamide branched chain transacylase; Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase; EC 2.3.1.168 from Bos taurus (Bovine)
PFams: Biotin_lipoyl, E3_binding, 2-oxoacid_dh
482 amino acids: PaperBLAST, CDD, Compare to cluster

ODB2_CAEEL / Q23571 Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial; Branched-chain alpha-keto acid dehydrogenase complex component E2; Dihydrolipoamide branched-chain transacylase E2; EC 2.3.1.168 from Caenorhabditis elegans
PFams: Biotin_lipoyl, E3_binding, 2-oxoacid_dh
448 amino acids: PaperBLAST, CDD, Compare to cluster

ODB2_ARATH / Q9M7Z1 Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial; Branched-chain alpha-keto acid dehydrogenase complex component E2; BCE2; BCKAD-E2; BCKADE2; Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex; Dihydrolipoamide branched chain transacylase; Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase; Protein DARK INDUCIBLE 3; EC 2.3.1.168 from Arabidopsis thaliana (Mouse-ear cress)
PFams: Biotin_lipoyl, E3_binding, 2-oxoacid_dh
483 amino acids: PaperBLAST, CDD, Compare to cluster

HP15_1631 Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase (EC 2.3.1.168) from Marinobacter adhaerens HP15
PFams: E3_binding, 2-oxoacid_dh
378 amino acids: PaperBLAST, CDD, Compare to cluster

SMc03203 Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase (EC 2.3.1.168) from Sinorhizobium meliloti 1021
PFams: Biotin_lipoyl, E3_binding, 2-oxoacid_dh
426 amino acids: PaperBLAST, CDD, Compare to cluster

PfGW456L13_3542 Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase (EC 2.3.1.168) from Pseudomonas fluorescens GW456-L13
PFams: Biotin_lipoyl, E3_binding, 2-oxoacid_dh
425 amino acids: PaperBLAST, CDD, Compare to cluster

Pf6N2E2_479 Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase (EC 2.3.1.168) from Pseudomonas fluorescens FW300-N2E2
PFams: Biotin_lipoyl, E3_binding, 2-oxoacid_dh
423 amino acids: PaperBLAST, CDD, Compare to cluster