Other Characterized Proteins Similar to liuC

Finding the characterized proteins for liuC (3-methylglutaconyl-CoA hydratase) in L-leucine catabolism

Or see clustering for step liuC

Or see all steps for L-leucine catabolism

Or cluster curated proteins matching a keyword

Definition of liuC

• Curated proteins or TIGRFams with EC 4.2.1.18
• UniProt sequence Q92VJ6: SubName: Full=Putative enoyl-CoA hydratase protein {ECO:0000313|EMBL:CAC49105.1}; EC=4.2.1.17 {ECO:0000313|EMBL:CAC49105.1};
• Comment: SM_b21126 (Q92VJ6) is a bit diverged and is confirmed by fitness data

Fetched 10 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 6 other characterized sequences. (Found 15 hits including self hits.)

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for liuC.)

A5N5C7 crotonase (EC 4.2.1.150) from Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680)
PFams: ECH_1, ECH_2
259 amino acids: PaperBLAST, CDD, metacyc::MONOMER-13469
43% identical to

Q1D5Y4 methylglutaconyl-CoA hydratase (EC 4.2.1.18) from Myxococcus xanthus
PFams: ECH_2, ECH_1
258 amino acids: PaperBLAST, CDD

FER4_USTMA / Q4PEN0 Enoyl-CoA isomerase/hydratase fer4; Fe-regulated protein 4; Ferrichrome A biosynthesis protein fer4; EC 4.2.1.17 from Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus)
PFams: ECH_1, ECH_2
274 amino acids: PaperBLAST, CDD, SwissProt::Q4PEN0
43% identical to

Q1D5Y4 methylglutaconyl-CoA hydratase (EC 4.2.1.18) from Myxococcus xanthus
PFams: ECH_2, ECH_1
258 amino acids: PaperBLAST, CDD

P52046 crotonase monomer (EC 4.2.1.150) from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
CRT_CLOAB / P52046 Short-chain-enoyl-CoA hydratase; 3-hydroxybutyryl-CoA dehydratase; Crotonase; EC 4.2.1.150 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
CH_091794 3-hydroxybutyryl-CoA dehydratase; EC 4.2.1.55 from Clostridium acetobutylicum
PFams: ECH_1, ECH_2
261 amino acids: PaperBLAST, CDD, CharProtDB::CH_091794
42% identical to

Q1D5Y4 methylglutaconyl-CoA hydratase (EC 4.2.1.18) from Myxococcus xanthus
PFams: ECH_2, ECH_1
258 amino acids: PaperBLAST, CDD

A4YI89 3-hydroxypropionyl-CoA dehydratase (EC 4.2.1.116) from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)
HPCD_METS5 / A4YI89 3-hydroxypropionyl-coenzyme A dehydratase; 3-hydroxypropionyl-CoA dehydratase; EC 4.2.1.116 from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)
A4YI89 3-hydroxypropionyl-CoA dehydratase (EC 4.2.1.116) from Metallosphaera sedula
PFams: ECH_1, ECH_2
259 amino acids: PaperBLAST, CDD, BRENDA::A4YI89
42% identical to

Q1D5Y4 methylglutaconyl-CoA hydratase (EC 4.2.1.18) from Myxococcus xanthus
PFams: ECH_2, ECH_1
258 amino acids: PaperBLAST, CDD

CRCH_SYNWW / Q0AVM1 Crotonyl-CoA hydratase; EC 4.2.1.150 from Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen)
PFams: ECH_1, ECH_2
260 amino acids: PaperBLAST, CDD, SwissProt::Q0AVM1
42% identical to

Q1D5Y4 methylglutaconyl-CoA hydratase (EC 4.2.1.18) from Myxococcus xanthus
PFams: ECH_2, ECH_1
258 amino acids: PaperBLAST, CDD

FADB_BACSU / P94549 Probable enoyl-CoA hydratase; EC 4.2.1.17 from Bacillus subtilis (strain 168)
PFams: ECH_1, ECH_2
258 amino acids: PaperBLAST, CDD, SwissProt::P94549
40% identical to

AUHM_MOUSE / Q9JLZ3 Methylglutaconyl-CoA hydratase, mitochondrial; AU-specific RNA-binding enoyl-CoA hydratase; AU-binding enoyl-CoA hydratase; muAUH; Itaconyl-CoA hydratase; EC 4.2.1.18; EC 4.2.1.56 from Mus musculus (Mouse)
PFams: ECH_1, ECH_2
314 amino acids: PaperBLAST, CDD