Other Characterized Proteins Similar to crr

GapMind for catabolism of small carbon sources

Other Characterized Proteins Similar to crr

Finding the characterized proteins for crr (glucose PTS, enzyme IIA) in D-maltose catabolism

Or see clustering for step crr

Or see all steps for D-maltose catabolism

Or cluster curated proteins matching a keyword

Definition of crr

Curated sequence CH_088352: glucose-specific phosphotransferase enzyme IIA component; EC 2.7.1.-. PTS system glucose-specific EIIA component; EIIA-Glc; EIII-Glc; Glucose-specific phosphotransferase enzyme IIA component. Glucose-specific phosphotransferase enzyme IIA component PTGA aka CRR aka GSR aka IEX aka TGS aka TRED aka B2417, component of Glucose porter (PtsG; GlcA; Umg) (transports D-glucose and α-methyl-D-glucopyranoside). Enzyme IIA^Glc (EC 2.7.1.199; EC 2.7.1.201; EC 2.7.1.192). Enzyme IIA^Glc (EC 2.7.1.199)
Curated sequence P0A283: PTS system glucose-specific EIIA component; EIIA-Glc; EIII-Glc; Glucose-specific phosphotransferase enzyme IIA component
Ignore hits to Q8L3C4 when looking for 'other' hits (IIA aka Crr, component of The N,N' -diacetylchitobiose Enzyme II (Toratani et al., 2008) (>80% identical to the E. coli enzyme (4.A.3.2.1)))
Comment: Ignore a close homlog in Serratia (TC 4.A.3.2.5 / Q8L3C4) which is reported to be the II-A component for N,N' -diacetylchitobiose (probably shared with other sugars).

Fetched 2 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 10 other characterized sequences. (Found 12 hits including self hits.)

Removing ignored items reduces this to 9 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for crr.)

P45604 protein-Npi-phosphohistidine-N-acetyl-D-glucosamine phosphotransferase (EC 2.7.1.193) from Klebsiella pneumoniae
PFams: PTS_EIIC, PTS_EIIB, PTS_EIIA_1
651 amino acids: PaperBLAST, CDD, BRENDA::P45604
53% identical to

PTGA_SALTY / P0A283 PTS system glucose-specific EIIA component; EIIA-Glc; EIII-Glc; Glucose-specific phosphotransferase enzyme IIA component from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
PFams: PTS_EIIA_1
Heteromeric, 169 amino acids: PaperBLAST, CDD

b0679 N-acetylglucosamine-specific PTS enzyme IIABC component (EC 2.7.1.193; EC 2.7.1.191) from Escherichia coli K-12 substr. MG1655
P09323 N-acetylglucosamine-specific PTS enzyme IIABC component (EC 2.7.1.193; EC 2.7.1.191) from Escherichia coli (strain K12)
PTW3C_ECOLI / P09323 PTS system N-acetylglucosamine-specific EIICBA component; EIICBA-Nag; EII-Nag; EC 2.7.1.193 from Escherichia coli (strain K12)
P09323 protein-Npi-phosphohistidine-N-acetyl-D-glucosamine phosphotransferase (EC 2.7.1.193) from Escherichia coli
TC 4.A.1.1.2 / P09323 N-Acetyl glucosamine (NAG) porter (NagE) from Escherichia coli
PFams: PTS_EIIC, PTS_EIIB, PTS_EIIA_1
648 amino acids: PaperBLAST, CDD, BRENDA::P09323
51% identical to

TC 4.A.1.1.9 / P20166 The glucose IICBA porter (PtsG) 44% identical to 4.A.1.1.1) from Bacillus subtilis
GB|CAB13262.1 PTS system glucose-specific EIICBA component; EC 2.7.1.-; EC 2.7.1.69 from Bacillus subtilis
PFams: PTS_EIIC, PTS_EIIB, PTS_EIIA_1
699 amino acids: PaperBLAST, CDD, CharProtDB::CH_001857
43% identical to

PTU3C_STACT / Q53922 PTS system glucoside-specific EIICBA component; EIICBA-Glc 2; EC 2.7.1.- from Staphylococcus carnosus (strain TM300)
TC 4.A.1.1.14 / Q53922 Glucose porter GlcB (IICBA). Glucose uptake is inhibited by methyl-α-D-glucoside, methyl-β-D-glucoside, p-nitrophenyl-α-D-glucoside, o-nitrophenyl-β-D-glucoside and salicin, but not by 2-deoxyglucose. Mannose and N-acetylglucosamine are not transported from Staphylococcus carnosus (strain TM300)
PFams: PTS_EIIC, PTS_EIIB, PTS_EIIA_1
692 amino acids: PaperBLAST, CDD, SwissProt::Q53922
42% identical to

PTG3C_STACT / Q57071 PTS system glucose-specific EIICBA component; EIICBA-Glc; EII-Glc; EIICBA-Glc 1; EC 2.7.1.199 from Staphylococcus carnosus (strain TM300)
TC 4.A.1.1.13 / Q57071 Glucose porter, GlcA (IICBA). Glucose uptake is inhibited by 2-deoxyglucose and methyl-β-D-glucoside from Staphylococcus carnosus (strain TM300)
PFams: PTS_EIIC, PTS_EIIB, PTS_EIIA_1
675 amino acids: PaperBLAST, CDD, SwissProt::Q57071
40% identical to

Q46072 protein-Npi-phosphohistidine-D-mannose phosphotransferase (EC 2.7.1.191); protein-Npi-phosphohistidine-D-glucose phosphotransferase (EC 2.7.1.199) from Corynebacterium glutamicum
PFams: PTS_EIIB, PTS_EIIC, PTS_EIIA_1
683 amino acids: PaperBLAST, CDD, BRENDA::Q46072
41% identical to

P12655 protein-Npi-phosphohistidine-sucrose phosphotransferase (EC 2.7.1.211) from Streptococcus mutans serotype c
GB|AAN59464.1 PTS system, sucrose-specific, EIIBCA component; EC 2.7.1.69 from Streptococcus mutans
PFams: PTS_EIIB, PTS_EIIC, PTS_EIIA_1
664 amino acids: PaperBLAST, CDD, BRENDA::P12655
40% identical to

b2417 Enzyme IIA^Glc (EC 2.7.1.199; EC 2.7.1.201; EC 2.7.1.192) from Escherichia coli K-12 substr. MG1655
P69783 Enzyme IIA^Glc (EC 2.7.1.199) from Escherichia coli (strain K12)
PTGA_ECOLI / P69783 PTS system glucose-specific EIIA component; EIIA-Glc; EIII-Glc; Glucose-specific phosphotransferase enzyme IIA component from Escherichia coli (strain K12)
TC 4.A.1.1.1 / P69783 Glucose-specific phosphotransferase enzyme IIA component PTGA aka CRR aka GSR aka IEX aka TGS aka TRED aka B2417, component of Glucose porter (PtsG; GlcA; Umg) (transports D-glucose and α-methyl-D-glucopyranoside) from Escherichia coli
GB|AAC75470.1 glucose-specific phosphotransferase enzyme IIA component; EC 2.7.1.- from Escherichia coli K12
PFams: PTS_EIIA_1
Heteromeric, 169 amino acids: PaperBLAST, CDD

AO356_17540 N-acetylglucosamine-specific PTS system, I, HPr, and IIA components (nagF) from Pseudomonas fluorescens FW300-N2C3
PFams: PTS_EIIA_1, PTS-HPr, PEP-utilisers_N, PEP-utilizers, PEP-utilizers_C
Heteromeric, 837 amino acids: PaperBLAST, CDD, reanno::pseudo5_N2C3_1:AO356_17540
40% identical to

PTW3C_BACSU / P39816 Putative PTS system glucosamine-specific EIICBA component; EC 2.7.1.193 from Bacillus subtilis (strain 168)
TC 4.A.1.1.6 / P39816 The glucosamine IICBA porter (GamP) (40% identical to 4.A.1.1.2) (Plumbridge 2015). The IIA domain in this protein can transfer the phosphoryl moiety to the maltose, N-acetylglucosamine, sucrose and trehalose PTS systems (MalP, NagP, SacP and TreP, respectively) from Bacillus subtilis
PFams: PTS_EIIC, PTS_EIIB, PTS_EIIA_1
631 amino acids: PaperBLAST, CDD, SwissProt::P39816
47% identical to

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for crr.)

TC 4.A.3.2.5 / Q8L3C4 IIA aka Crr, component of The N,N' -diacetylchitobiose Enzyme II (Toratani et al., 2008) (>80% identical to the E. coli enzyme (4.A.3.2.1)) from Serratia marcescens
PFams: PTS_EIIA_1
Heteromeric, 169 amino acids: PaperBLAST, CDD, TCDB::Q8L3C4
97% identical to