Clusters of Characterized Proteins

Clustering the characterized proteins for cmtB (mannitol phosphotransferase system, EII-A component CmtB/MtlF) in D-mannitol catabolism

Or see other characterized proteins similar to cmtB

Or see all steps for D-mannitol catabolism

Or cluster curated proteins matching a keyword

Definition of cmtB

• Curated sequence CMTB-MONOMER: mannitol-specific PTS enzyme IIA component CmtB (EC 2.7.1.197). mannitol-specific PTS enzyme IIA component CmtB (EC 2.7.1.197)
• Curated sequence P17876: Mannitol-specific phosphotransferase enzyme IIA component; EIIA; EIII; PTS system mannitol-specific EIIA component
• Curated sequence C0H3V2: Mannitol-specific phosphotransferase enzyme IIA component, component of The mannitol porter (MtlA) (mannitol-1-P forming), MtlAF
• UniProt sequence O65991: SubName: Full=MtlF {ECO:0000313|EMBL:AAC12850.1};
• UniProt sequence Q45420: RecName: Full=Mannitol-specific phosphotransferase enzyme IIA component {ECO:0000250|UniProtKB:P0A0E0}; AltName: Full=EIIA {ECO:0000250|UniProtKB:P0A0E0}; AltName: Full=EIII {ECO:0000303|PubMed:8824601}; AltName: Full=PTS system mannitol-specific EIIA component {ECO:0000250|UniProtKB:P0A0E0};
• Ignore hits to P0A0E0 when looking for 'other' hits (Mannitol-specific phosphotransferase enzyme IIA component; EIIA; EIII; PTS system mannitol-specific EIIA component)
• Comment: For C. acetobutylicum, the mtlF component is is O65991 (see PMID:11160802); and in Geobacillus it is Q45420 (PMID:824601; Genbank U18943.1). There is also a paper about the EII-A and EII-BC system from S. aureus, see PMID:3064811 and SwissProt P0A0E0, but I'm not sure this is the correct accession, so ignore it.

Fetched 5 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 4 of these sequences

Found 1 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 139-145 amino acids (1/4 heteromeric)

PTMA_STACT / P17876 Mannitol-specific phosphotransferase enzyme IIA component; EIIA; EIII; PTS system mannitol-specific EIIA component from Staphylococcus carnosus (strain TM300)
PFams: PTS_EIIA_2
144 amino acids: PaperBLAST, CDD, Compare to cluster

TC 4.A.2.1.5 / C0H3V2 Mannitol-specific phosphotransferase enzyme IIA component, component of The mannitol porter (MtlA) (mannitol-1-P forming), MtlAF from Bacillus subtilis (strain 168)
PFams: PTS_EIIA_2
Heteromeric, 143 amino acids: PaperBLAST, CDD, Compare to cluster

O65991 MtlF
139 amino acids: PaperBLAST, CDD, Compare to cluster

Q45420 Mannitol-specific phosphotransferase enzyme IIA component {ECO:0000250|UniProtKB:P0A0E0}; EIIA {ECO:0000250|UniProtKB:P0A0E0}; AltName: Full=EIII {ECO:0000303|PubMed:8824601}; AltName: Full=PTS system mannitol-specific EIIA component {ECO:0000250|UniProtKB:P0A0E0}
145 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (1/1 heteromeric)

b2934 mannitol-specific PTS enzyme IIA component CmtB (EC 2.7.1.197) from Escherichia coli K-12 substr. MG1655
P69824 mannitol-specific PTS enzyme IIA component CmtB (EC 2.7.1.197) from Escherichia coli (strain K12)
PFams: PTS_EIIA_2
Heteromeric, 147 amino acids: PaperBLAST, CDD