Clusters of Characterized Proteins

GapMind for catabolism of small carbon sources

Clusters of Characterized Proteins

Clustering the characterized proteins for mt2d (mannitol 2-dehydrogenase) in D-mannitol catabolism

Or see other characterized proteins similar to mt2d

Or see all steps for D-mannitol catabolism

Or cluster curated proteins matching a keyword

Definition of mt2d

Curated proteins or TIGRFams with EC 1.1.1.67
Curated proteins or TIGRFams with EC 1.1.1.138
UniProt sequence P33216: RecName: Full=Mannitol 2-dehydrogenase; Short=M2DH; Short=MDH; EC=1.1.1.67;
Comment: SwissProt P33216 was shown to have this activity (PMID:2789134; PMID:8254318)

Fetched 15 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 15 of these sequences

Found 3 clusters of similar sequences. Download as table or as draft rules or view by cluster

Agaricus bisporus

MTDH_AGABI / O93868 NADP-dependent mannitol dehydrogenase; MtDH; Mannitol 2-dehydrogenase [NADP(+)]; EC 1.1.1.138 from Agaricus bisporus (White button mushroom)
PFams: adh_short, KR, adh_short_C2
262 amino acids: PaperBLAST, CDD (Cluster 1)

Alternaria alternata

MTDH_ALTAL / P0C0Y4 NADP-dependent mannitol dehydrogenase; MtDH; Mannitol 2-dehydrogenase [NADP(+)]; Allergen Alt a 8; EC 1.1.1.138 from Alternaria alternata (Alternaria rot fungus) (Torula alternata)
P0C0Y4 mannitol 2-dehydrogenase (NADP+) (EC 1.1.1.138) from Alternaria alternata
PFams: adh_short, KR, adh_short_C2
266 amino acids: PaperBLAST, CDD (Cluster 1)

Aspergillus fumigatus

M2DH_ASPFU / Q4WQY4 Mannitol 2-dehydrogenase; M2DH; MDH; EC 1.1.1.67 from Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Q4WQY4 mannitol 2-dehydrogenase (EC 1.1.1.67) from Aspergillus fumigatus
PFams: Mannitol_dh, Mannitol_dh_C
502 amino acids: PaperBLAST, CDD (Cluster 3)

Cladosporium herbarum

MTDH_DAVTA / P0C0Y5 NADP-dependent mannitol dehydrogenase; MtDH; Mannitol 2-dehydrogenase [NADP(+)]; Allergen Cla h 8; EC 1.1.1.138 from Davidiella tassiana (Mycosphaerella tassiana) (Cladosporium herbarum)
P0C0Y5 mannitol 2-dehydrogenase (NADP+) (EC 1.1.1.138) from Cladosporium herbarum
PFams: adh_short, KR, adh_short_C2
267 amino acids: PaperBLAST, CDD (Cluster 1)

Davidiella tassiana

Hypocrea jecorina

Q8NK50 D-mannitol 2-dehydrogenase (EC 1.1.1.67) from Hypocrea jecorina
MTDH_HYPJE / Q8NK50 NADP-dependent mannitol dehydrogenase; MtDH; Mannitol 2-dehydrogenase [NADP(+)]; EC 1.1.1.138 from Hypocrea jecorina (Trichoderma reesei)
Q8NK50 L-xylulose reductase (EC 1.1.1.10) from Trichoderma reesei
PFams: adh_short, KR, adh_short_C2
266 amino acids: PaperBLAST, CDD (Cluster 1)

Lactobacillus reuteri

Q6ECH5 mannitol 2-dehydrogenase (EC 1.1.1.67) from Lactobacillus reuteri
PFams: ADH_N, Shikimate_DH, ADH_zinc_N
336 amino acids: PaperBLAST, CDD (Cluster 2)

Leuconostoc mesenteroides

Q8KQG6 mannitol 2-dehydrogenase (EC 1.1.1.67) from Leuconostoc mesenteroides
PFams: ADH_N, ADH_zinc_N
338 amino acids: PaperBLAST, CDD (Cluster 2)

Leuconostoc pseudomesenteroides

Q83VI5 mannitol 2-dehydrogenase (EC 1.1.1.67) from Leuconostoc pseudomesenteroides
PFams: ADH_N, ADH_zinc_N
338 amino acids: PaperBLAST, CDD (Cluster 2)

Neosartorya fumigata

Organism unknown

P33216 Mannitol 2-dehydrogenase; Short=M2DH; Short=MDH; EC=1.1.1.67
477 amino acids: PaperBLAST, CDD (Cluster 3)

Pseudomonas fluorescens

O08355 mannitol 2-dehydrogenase (EC 1.1.1.67) from Pseudomonas fluorescens
PFams: Mannitol_dh, Mannitol_dh_C
493 amino acids: PaperBLAST, CDD (Cluster 3)

Saccharina japonica

R9UHL6 mannitol 2-dehydrogenase (EC 1.1.1.67) from Saccharina japonica
PFams: Mannitol_dh, Mannitol_dh_C
668 amino acids: PaperBLAST, CDD (Cluster 3)

Saccharomyces cerevisiae

DSF1_YEAST / P0CX08 Mannitol dehydrogenase DSF1; Deletion suppressor of MPT5 mutation protein 1; EC 1.1.1.67 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
MAN2_YEAST / P0CX09 Mannitol dehydrogenase 2; EC 1.1.1.67 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Mannitol_dh, Mannitol_dh_C
502 amino acids: PaperBLAST, CDD (Cluster 3)

Thermotoga maritima

Q9WYD4 mannitol 2-dehydrogenase (EC 1.1.1.67) from Thermotoga maritima
PFams: ADH_N
317 amino acids: PaperBLAST, CDD (Cluster 2)

Trichoderma reesei

Tuber borchii

Q1ACW3 mannitol 2-dehydrogenase (NADP+) (EC 1.1.1.138) from Tuber borchii
PFams: ADH_N, Glu_dehyd_C, ADH_zinc_N, ADH_zinc_N_2
345 amino acids: PaperBLAST, CDD (Cluster 2)

Yarrowia lipolytica

SDR_YARLI / Q6CEE9 Probable NADP-dependent mannitol dehydrogenase; MtDH; Mannitol 2-dehydrogenase [NADP(+)]; Short chain dehydrogenase/reductase; YlSDR; EC 1.1.1.138 from Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
PFams: adh_short, KR, adh_short_C2
278 amino acids: PaperBLAST, CDD (Cluster 1)