Other Characterized Proteins Similar to mtlE

GapMind for catabolism of small carbon sources

Finding the characterized proteins for mtlE (polyol ABC transporter, substrate-binding component MtlE/SmoE) in D-mannitol catabolism

Or see clustering for step mtlE

Definition of mtlE

Curated sequence O30491: MtlE, component of The polyol (mannitol, glucitol (sorbitol), arabitol (arabinitol; lyxitol)) uptake porter, MtlEFGK
Curated sequence GFF2493: ABC transporter for D-Mannitol, D-Mannose, and D-Sorbitol, periplasmic substrate-binding protein
Curated sequence PfGW456L13_3042: ABC transporter for D-Mannitol, D-Mannose, and D-Mannose, periplasmic substrate-binding component
Curated sequence AO353_25880: ABC transporter for D-mannitol and D-mannose, periplasmic substrate-binding component
Ignore hits to AO356_00025 when looking for 'other' hits (ABC transporter for D-Sorbitol, periplasmic substrate-binding component)
Ignore hits to Pf6N2E2_1963 when looking for 'other' hits (ABC transporter for D-sorbitol, periplasmic substrate-binding component)
Curated sequence O30831: SmoE, component of Hexitol (glucitol; mannitol) porter
Comment: MtlEFGK in several strains of Pseudomonas fluorescens or Pseudomonas simiae, or smoEFGK in Rhodopseudomonas sphaeroides. (The Rhodopseudomonas system was missed by the query; it is annotated as a hexitol transporter.) For all components, ignore simlarity to close homologs in FW300-N2C3 or FW300-N2E2, annotated as transporting sorbitol only.

Fetched 5 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 5 other characterized sequences. (Found 10 hits including self hits.)

Removing ignored items reduces this to 3 close sequences.

(Sequences that are similar to these will not be high-confidence candidates for mtlE.)

PGA1_c13210 ABC transporter for D-Sorbitol, periplasmic substrate-binding component from Phaeobacter inhibens BS107
PFams: SBP_bac_1, SBP_bac_8
Heteromeric, 433 amino acids: PaperBLAST, CDD, reanno::Phaeo:GFF1305
73% identical to

TC 3.A.1.1.5 / O30831 SmoE, component of Hexitol (glucitol; mannitol) porter from Rhodobacter sphaeroides (Rhodopseudomonas sphaeroides)
PFams: SBP_bac_1, SBP_bac_8
Heteromeric, 436 amino acids: PaperBLAST, CDD

BPHYT_RS16115 ABC transporter for D-Sorbitol, periplasmic substrate-binding component from Burkholderia phytofirmans PsJN
PFams: SBP_bac_1, SBP_bac_8
Heteromeric, 440 amino acids: PaperBLAST, CDD, reanno::BFirm:BPHYT_RS16115
61% identical to

TC 3.A.1.1.49 / O30491 MtlE, component of The polyol (mannitol, glucitol (sorbitol), arabitol (arabinitol; lyxitol)) uptake porter, MtlEFGK from Pseudomonas fluorescens
PFams: SBP_bac_1, SBP_bac_8
Heteromeric, 436 amino acids: PaperBLAST, CDD

Ac3H11_2944 ABC transporter for D-Sorbitol, periplasmic substrate-binding component from Acidovorax sp. GW101-3H11
PFams: SBP_bac_1
Heteromeric, 443 amino acids: PaperBLAST, CDD, reanno::acidovorax_3H11:Ac3H11_2944
59% identical to

(Sequences that are similar to these will still be high-confidence candidates for mtlE.)

AO356_00025 ABC transporter for D-Sorbitol, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2C3
PFams: SBP_bac_8, SBP_bac_1
Heteromeric, 436 amino acids: PaperBLAST, CDD, reanno::pseudo5_N2C3_1:AO356_00025
74% identical to

Pf6N2E2_1963 ABC transporter for D-sorbitol, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E2
PFams: SBP_bac_8, SBP_bac_1
Heteromeric, 436 amino acids: PaperBLAST, CDD, reanno::pseudo6_N2E2:Pf6N2E2_1963
74% identical to