# pathway myoinositol step HMIT # Cluster 1 580-648 amino acids (not heteromeric) # CharProtDB::CH_091598,SwissProt::O23492,TCDB::O23492 RF|NP_193381.1;; INT4_ARATH;; 2.A.1.1.62 inositol transporter 4;; Inositol transporter 4; Myo-inositol-proton symporter INT4; Protein INOSITOL TRANSPORTER 4;; High affinity (0.24mM) plasma membrane myoinositol-specific H+ symporter, INT4 Arabidopsis thaliana;; Arabidopsis thaliana (Mouse-ear cress);; Arabidopsis thaliana (Mouse-ear cress) # SwissProt::Q921A2 MYCT_RAT Proton myo-inositol cotransporter; H(+)-myo-inositol cotransporter; Hmit; H(+)-myo-inositol symporter; Solute carrier family 2 member 13 Rattus norvegicus (Rat) # SwissProt::Q96QE2,TCDB::Q96QE2 MYCT_HUMAN;; 2.A.1.1.25 Proton myo-inositol cotransporter; H(+)-myo-inositol cotransporter; Hmit; H(+)-myo-inositol symporter; Solute carrier family 2 member 13;; Myoinositol:H+ symporter, HMIT (also transport other inositols including scyllo-, muco- and chiro-, but not allo-inositol) (Aouameur et al., 2007). Expressed in the Golgi of the hippocampus and cortex. May also transport inositoltriphosphate (Di Daniel et al., 2009). Interacts directly with γ-secretase (9.B.47.1.1) to regulate its activity and the production of Abeta production, important in Alzheimer's disease Homo sapiens (Human);; Homo sapiens (Human) # SwissProt::Q9C757,TCDB::Q9C757 INT2_ARATH;; 2.A.1.1.63 Probable inositol transporter 2;; Low affinity inositol (myoinsoitol (Km = 1 mM), scylloinositol, d-chiroinositol and mucoinositol):H+ symporter (expressed in the anther tapetum, the vasculature, and the leaf mesophyll Arabidopsis thaliana (Mouse-ear cress);; Arabidopsis thaliana (Mouse-ear cress) # SwissProt::Q9ZQP6 INT3_ARATH Probable inositol transporter 3 Arabidopsis thaliana (Mouse-ear cress) Cluster1 inositol transporter 4;; Inositol transporter 4; Myo-inositol-proton symporter INT4; Protein INOSITOL TRANSPORTER 4;; High affinity (0.24mM) plasma membrane myoinositol-specific H+ symporter, INT4 curated:CharProtDB::CH_091598 curated:SwissProt::Q921A2 curated:SwissProt::Q96QE2 curated:SwissProt::Q9C757 curated:SwissProt::Q9ZQP6