Other Characterized Proteins Similar to iolJ

GapMind for catabolism of small carbon sources

Other Characterized Proteins Similar to iolJ

Finding the characterized proteins for iolJ (5-dehydro-2-deoxyphosphogluconate aldolase) in myo-inositol catabolism

Or see clustering for step iolJ

Or see all steps for myo-inositol catabolism

Or cluster curated proteins matching a keyword

Definition of iolJ

Curated proteins or TIGRFams with EC 4.1.2.29
Comment: DUF2090 appears to be a substitute for the aldolase. It is distantly related to aldolases and is found fused to iolC in inositol degradation clusters that lack any apparent iolJ. Fitness data confirms that these fusion proteins are required for myo-inositol utilization (but does not prove that the DUF2090 domain is required). These proteins are included in iolJ via their reannotations.

Fetched 11 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 5 other characterized sequences. (Found 16 hits including self hits.)

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for iolJ.)

I3EBM6 fructose-bisphosphate aldolase (EC 4.1.2.13) from Bacillus methanolicus
PFams: F_bP_aldolase
285 amino acids: PaperBLAST, CDD, BRENDA::I3EBM6
59% identical to

P42420 2-deoxy-5-keto-D-gluconate 6-phosphate aldolase (EC 4.1.2.29) from Bacillus subtilis (strain 168)
IOLJ_BACSU / P42420 6-phospho-5-dehydro-2-deoxy-D-gluconate aldolase; DKGP aldolase; EC 4.1.2.29 from Bacillus subtilis (strain 168)
PFams: F_bP_aldolase
290 amino acids: PaperBLAST, CDD

ALF_BACSU / P13243 Probable fructose-bisphosphate aldolase; FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase; EC 4.1.2.13 from Bacillus subtilis (strain 168)
PFams: F_bP_aldolase
285 amino acids: PaperBLAST, CDD, SwissProt::P13243
57% identical to

Q5HE75 fructose-bisphosphate aldolase (EC 4.1.2.13) from Staphylococcus aureus
PFams: F_bP_aldolase
286 amino acids: PaperBLAST, CDD, BRENDA::Q5HE75
56% identical to

ALF_STRR6 / P0A4S2 Fructose-bisphosphate aldolase; FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase; EC 4.1.2.13 from Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
PFams: F_bP_aldolase
293 amino acids: PaperBLAST, CDD, SwissProt::P0A4S2
41% identical to

ALF_THECA / Q703I2 Fructose-bisphosphate aldolase; FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase; EC 4.1.2.13 from Thermus caldophilus
PFams: F_bP_aldolase
305 amino acids: PaperBLAST, CDD, SwissProt::Q703I2
40% identical to