Other Characterized Proteins Similar to iolT

GapMind for catabolism of small carbon sources

Other Characterized Proteins Similar to iolT

Finding the characterized proteins for iolT (myo-inositol:H+ symporter) in myo-inositol catabolism

Or see clustering for step iolT

Or see all steps for myo-inositol catabolism

Or cluster curated proteins matching a keyword

Definition of iolT

Curated sequence Q8VZR6: Inositol transporter 1. The tonoplast H+:Inositol symporter 1, Int1 (mediates efflux from the tonoplast to the cytoplasm (Schneider et al., 2008) (most similar to 2.A.1.1.63 and 2.A.1.1.62)
Curated sequence CH_091483: polyol transporter 5. Polyol transporter 5; Protein POLYOL TRANSPORTER 5; AtPLT5; Sugar-proton symporter PLT5. The broad specificity sugar/sugar alcohol (myo-inositol, glycerol, ribose, sorbitol, mannitol, xylitol, erythritol, etc) H+ symporter, AtPLT5 (transports a wide range of hexoses, pentoses, tetroses, sugar alcohols and a sugar acid, but not disaccharides) (Reinders et al., 2005) (expressed in roots, leaves and floral organs)
Curated sequence CH_091623: Myo-inositol transporter 1. Myo-inositol transporter 1. Myoinositol:H+ symporter
Curated sequence CH_123508: myo-inositol transporter 2
Curated sequence O34718: Major myo-inositol transporter IolT. Major myoinositol:H+ symporter, IolT
Curated sequence P30606: Myo-inositol transporter 2. Myo-inositol transporter 2
Curated sequence P87110: Myo-inositol transporter 2. MFS myo-inositol transporter
Curated sequence Q10286: Myo-inositol transporter 1. myo-inositol transporter Itr1
Curated sequence A8DCT2: Myo inositol uptake porter of 574 aas and 12 TMSs, Fst1
Curated sequence AIU34725.1: Myo-inositol-specific uptake transporter, ITR1 of 509 aas and 12 TMSs
Curated sequence Q01440: Myoinositol:H+ symporter, MIT
Curated sequence Q8NTX0: Myo-Inositol uptake porter, IolT1 (Km=0.2mM)
Curated sequence E1WAV3: Major myo-inositol transporter, IolT1, of 456 aas
Curated sequence E1WAV4: Minor myo-inositol transporter, IolT2, of 478 aas
Curated sequence Q8NL90: Myo-Inositol (Km=0.45mM) uptake porter, IolT2 (Krings et al., 2006). Can not transport D-glucose
Curated sequence CH_123411: potential myo-inositol transporter
Curated sequence CH_124311: major myo-inositol transporter iolT
Comment: Distantly related transporters with the same domain content were grouped together into iolT

Fetched 17 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 11 other characterized sequences. (Found 28 hits including self hits.)

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for iolT.)

TC 2.A.1.1.79 / Q1XF07 Polyol (xylitol):H+ symporter, PLT4 from Lotus japonicus
PFams: Sugar_tr, MFS_1
519 amino acids: PaperBLAST, CDD, TCDB::Q1XF07
76% identical to

PLT5_ARATH / Q8VZ80 Polyol transporter 5; Protein POLYOL TRANSPORTER 5; AtPLT5; Sugar-proton symporter PLT5 from Arabidopsis thaliana (Mouse-ear cress)
TC 2.A.1.1.34 / Q8VZ80 The broad specificity sugar/sugar alcohol (myo-inositol, glycerol, ribose, sorbitol, mannitol, xylitol, erythritol, etc) H+ symporter, AtPLT5 (transports a wide range of hexoses, pentoses, tetroses, sugar alcohols and a sugar acid, but not disaccharides) (Reinders et al., 2005) (expressed in roots, leaves and floral organs) from Arabidopsis thaliana (Mouse-ear cress)
RF|NP_188513.1 polyol transporter 5 from Arabidopsis thaliana
PFams: Sugar_tr, MFS_1
539 amino acids: PaperBLAST, CDD

CH_124121 arabinose-proton symporter from Magnaporthe grisea 70-15
PFams: Sugar_tr, MFS_1, TRI12
575 amino acids: PaperBLAST, CDD, CharProtDB::CH_124121
72% identical to

TC 2.A.1.1.126 / A8DCT2 Myo inositol uptake porter of 574 aas and 12 TMSs, Fst1 from Gibberella moniliformis
PFams: Sugar_tr, MFS_1, TRI12
574 amino acids: PaperBLAST, CDD

TC 2.A.1.1.123 / AIU41385.1 Sorbitol (D-Glucitol):H+ co-transporter, SOT1 (Km for sorbitol of 0.64 mM) of 509 aas and 12 TMSs (Gao et al. 2003). SOT1 of P. cerasus is expressed throughout fruit development, but especially when growth and sorbitol accumulation rates are highest. In leaves, PcSOT1 expression is highest in young, expanding tissues, but substantially less in mature leaves from Prunus salicina
PFams: Sugar_tr, MFS_1
509 amino acids: PaperBLAST, CDD, TCDB::AIU41385.1
68% identical to

TC 2.A.1.1.75 / Q9XIH7 The fructose/xylose:H+ symporter, PMT1 (polyol monosaccharide transporter-1). Also transports other substrates at lower rates. PMT2 is largely of the same sequence and function. Both are present in pollen and young xylem cells (Klepek et al., 2005). A similar ortholog has been identifed in pollen grains of Petunia hybrida from Arabidopsis thaliana
PFams: Sugar_tr, MFS_1
511 amino acids: PaperBLAST, CDD, TCDB::Q9XIH7
67% identical to

TC 2.A.1.1.122 / AGG19156.1 Sorbitol (glucitol):H+ co-transporter, SOT2 (Km for sorbitol of 0.81 mM) of 491 aas and 12 TMSs (Gao et al. 2003). SOT2 of Prunus cerasus is mainly expressed only early in fruit development and not in leaves from Pyrus pyrifolia
PFams: Sugar_tr, MFS_1
491 amino acids: PaperBLAST, CDD, TCDB::AGG19156.1
69% identical to

TC 2.A.1.1.33 / Q8NJ22 Fructose:H+ symporter, Frt1 from Kluyveromyces lactis (Yeast)
PFams: Sugar_tr, MFS_1
566 amino acids: PaperBLAST, CDD, TCDB::Q8NJ22
54% identical to

TC 2.A.1.1.126 / A8DCT2 Myo inositol uptake porter of 574 aas and 12 TMSs, Fst1 from Gibberella moniliformis
PFams: Sugar_tr, MFS_1, TRI12
574 amino acids: PaperBLAST, CDD

TC 2.A.1.1.39 / P49374 The high affinity glucose transporter, Hgt1 from Kluyveromyces lactis (Yeast) (Candida sphaerica)
PFams: Sugar_tr, MFS_1
551 amino acids: PaperBLAST, CDD, TCDB::P49374
45% identical to

TC 2.A.1.1.131 / AIU34725.1 Myo-inositol-specific uptake transporter, ITR1 of 509 aas and 12 TMSs from Pneumocystis carinii
PFams: Sugar_tr, MFS_1, MFS_1
507 amino acids: PaperBLAST, CDD

CH_122958 high affinity glucose transporter from Candida albicans
PFams: Sugar_tr, MFS_1
545 amino acids: PaperBLAST, CDD, CharProtDB::CH_122958
44% identical to

TC 2.A.1.1.131 / AIU34725.1 Myo-inositol-specific uptake transporter, ITR1 of 509 aas and 12 TMSs from Pneumocystis carinii
PFams: Sugar_tr, MFS_1, MFS_1
507 amino acids: PaperBLAST, CDD

HGT1_CANAL / A0A1D8PCL1 High-affinity glucose transporter 1 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
PFams: Sugar_tr, MFS_1
545 amino acids: PaperBLAST, CDD, SwissProt::A0A1D8PCL1
44% identical to

TC 2.A.1.1.131 / AIU34725.1 Myo-inositol-specific uptake transporter, ITR1 of 509 aas and 12 TMSs from Pneumocystis carinii
PFams: Sugar_tr, MFS_1, MFS_1
507 amino acids: PaperBLAST, CDD

CH_123257 potential high affinity glucose transporter from Candida albicans
PFams: Sugar_tr, MFS_1
545 amino acids: PaperBLAST, CDD, CharProtDB::CH_123257
43% identical to

TC 2.A.1.1.131 / AIU34725.1 Myo-inositol-specific uptake transporter, ITR1 of 509 aas and 12 TMSs from Pneumocystis carinii
PFams: Sugar_tr, MFS_1, MFS_1
507 amino acids: PaperBLAST, CDD

b4031 D-xylose:H⁺ symporter from Escherichia coli K-12 substr. MG1655
P0AGF4 D-xylose:H⁺ symporter from Escherichia coli (strain K12)
XYLE_ECOLI / P0AGF4 D-xylose-proton symporter; D-xylose transporter from Escherichia coli (strain K12)
TC 2.A.1.1.3 / P0AGF4 Xylose (xylopyranose):H+ symporter of 491 aas and 12 TMSs from Escherichia coli
CH_109760 D-xylose-proton symporter from Escherichia coli K12
PFams: Sugar_tr, MFS_1, MFS_1
491 amino acids: PaperBLAST, CDD, CharProtDB::CH_109760
41% identical to

TC 2.A.1.1.120 / E1WAV3 Major myo-inositol transporter, IolT1, of 456 aas from Salmonella typhimurium (strain SL1344)
PFams: Sugar_tr, MFS_1
456 amino acids: PaperBLAST, CDD