# pathway myoinositol step iolT # Cluster 1 473-609 amino acids (not heteromeric) # SwissProt::Q8VZR6,TCDB::Q8VZR6 INT1_ARATH;; 2.A.1.1.66 Inositol transporter 1;; The tonoplast H+:Inositol symporter 1, Int1 (mediates efflux from the tonoplast to the cytoplasm (Schneider et al., 2008) (most similar to 2.A.1.1.63 and 2.A.1.1.62) Arabidopsis thaliana (Mouse-ear cress);; Arabidopsis thaliana (Mouse-ear cress) # CharProtDB::CH_091483,SwissProt::Q8VZ80,TCDB::Q8VZ80 RF|NP_188513.1;; PLT5_ARATH;; 2.A.1.1.34 polyol transporter 5;; Polyol transporter 5; Protein POLYOL TRANSPORTER 5; AtPLT5; Sugar-proton symporter PLT5;; The broad specificity sugar/sugar alcohol (myo-inositol, glycerol, ribose, sorbitol, mannitol, xylitol, erythritol, etc) H+ symporter, AtPLT5 (transports a wide range of hexoses, pentoses, tetroses, sugar alcohols and a sugar acid, but not disaccharides) (Reinders et al., 2005) (expressed in roots, leaves and floral organs) Arabidopsis thaliana;; Arabidopsis thaliana (Mouse-ear cress);; Arabidopsis thaliana (Mouse-ear cress) # CharProtDB::CH_091623,SwissProt::P30605,TCDB::P30605 RF|NP_010785.1;; ITR1_YEAST;; 2.A.1.1.8 Myo-inositol transporter 1;; Myo-inositol transporter 1;; Myoinositol:H+ symporter Saccharomyces cerevisiae;; Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast);; Saccharomyces cerevisiae (Baker's yeast) # CharProtDB::CH_123508 myo-inositol transporter 2 Candida albicans # SwissProt::O34718,TCDB::O34718 IOLT_BACSU;; 2.A.1.1.26 Major myo-inositol transporter IolT;; Major myoinositol:H+ symporter, IolT Bacillus subtilis (strain 168);; Bacillus subtilis # SwissProt::P30606,TCDB::P30606 ITR2_YEAST;; 2.A.1.1.104 Myo-inositol transporter 2;; Myo-inositol transporter 2 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast);; Saccharomyces cerevisiae (strain ATCC 204508 / S288c) # SwissProt::P87110,CharProtDB::CH_125434 ITR2_SCHPO;; RF|NP_593320.1 Myo-inositol transporter 2;; MFS myo-inositol transporter Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast);; Schizosaccharomyces pombe # SwissProt::Q10286,CharProtDB::CH_125663 ITR1_SCHPO;; GI|1420856 Myo-inositol transporter 1;; myo-inositol transporter Itr1 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast);; Schizosaccharomyces pombe # TCDB::A8DCT2 2.A.1.1.126 Myo inositol uptake porter of 574 aas and 12 TMSs, Fst1 Gibberella moniliformis # TCDB::AIU34725.1 2.A.1.1.131 Myo-inositol-specific uptake transporter, ITR1 of 509 aas and 12 TMSs Pneumocystis carinii # TCDB::Q01440 2.A.1.1.20 Myoinositol:H+ symporter, MIT Leishmania donovani # TCDB::Q8NTX0 2.A.1.1.53 Myo-Inositol uptake porter, IolT1 (Km=0.2mM) Corynebacterium glutamicum (Brevibacterium flavum) Cluster1 Inositol transporter 1;; The tonoplast H+:Inositol symporter 1, Int1 (mediates efflux from the tonoplast to the cytoplasm (Schneider et al., 2008) (most similar to 2.A.1.1.63 and 2.A.1.1.62) curated:SwissProt::Q8VZR6 curated:CharProtDB::CH_091483 curated:CharProtDB::CH_091623 curated:CharProtDB::CH_123508 curated:SwissProt::O34718 curated:SwissProt::P30606 curated:SwissProt::P87110 curated:SwissProt::Q10286 curated:TCDB::A8DCT2 curated:TCDB::AIU34725.1 curated:TCDB::Q01440 curated:TCDB::Q8NTX0 # Cluster 2 456-508 amino acids (not heteromeric) # TCDB::E1WAV3 2.A.1.1.120 Major myo-inositol transporter, IolT1, of 456 aas Salmonella typhimurium (strain SL1344) # TCDB::E1WAV4 2.A.1.1.121 Minor myo-inositol transporter, IolT2, of 478 aas Salmonella typhimurium (strain SL1344) # TCDB::Q8NL90 2.A.1.1.54 Myo-Inositol (Km=0.45mM) uptake porter, IolT2 (Krings et al., 2006).  Can not transport D-glucose Corynebacterium glutamicum (Brevibacterium flavum) Cluster2 Major myo-inositol transporter, IolT1, of 456 aas curated:TCDB::E1WAV3 curated:TCDB::E1WAV4 curated:TCDB::Q8NL90 # Cluster 3 630-638 amino acids (not heteromeric) # CharProtDB::CH_123411 potential myo-inositol transporter Candida albicans # CharProtDB::CH_124311 major myo-inositol transporter iolT Magnaporthe grisea 70-15 Cluster3 potential myo-inositol transporter curated:CharProtDB::CH_123411 curated:CharProtDB::CH_124311