Other Characterized Proteins Similar to paaG

Finding the characterized proteins for paaG (1,2-epoxyphenylacetyl-CoA isomerase / 2-(oxepinyl)acetyl-CoA isomerase / didehydroadipyl-CoA isomerase ) in phenylacetate catabolism

Or see clustering for step paaG

Or see all steps for phenylacetate catabolism

Or cluster curated proteins matching a keyword

Definition of paaG

• Curated proteins or TIGRFams with EC 5.3.3.18
• Comment: In MetaCyc, PaaG is described as a 1,2-epoxyphenylacetyl-CoA isomerase, but it is now thought to isomerize 2-(oxepinyl)acetyl-CoA to oxepin-CoA as well as cis-3,4-didehydroadiyplCoA to trans-2,3-didehydroadiypl-CoA (see PMID:31689071).

Fetched 2 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 2 other characterized sequences. (Found 4 hits including self hits.)

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for paaG.)

Q9L4S8 2-cyclohexenylcarbonyl-CoA Δ-isomerase monomer (EC 5.3.3.3) from Streptomyces collinus
PFams: ECH_1, ECH_2
269 amino acids: PaperBLAST, CDD, metacyc::MONOMER-20787
46% identical to

Q5SLK3 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase (EC 5.3.3.18) from Thermus thermophilus
PFams: ECH_1, ECH_2
254 amino acids: PaperBLAST, CDD

A4YDS4 crotonyl-CoA hydratase/(S)-3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.35; EC 4.2.1.150) from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)
A4YDS4 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35); short-chain-enoyl-CoA hydratase (EC 4.2.1.150) from Metallosphaera sedula
PFams: 3HCDH_N, NAD_binding_2, 3HCDH, 3HCDH, ECH_1, ECH_2
651 amino acids: PaperBLAST, CDD, BRENDA::A4YDS4
40% identical to

Q5SLK3 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase (EC 5.3.3.18) from Thermus thermophilus
PFams: ECH_1, ECH_2
254 amino acids: PaperBLAST, CDD