Clusters of Characterized Proteins

Clustering the characterized proteins for aroP (L-phenylalanine:H+ symporter AroP) in L-phenylalanine catabolism

Or see other characterized proteins similar to aroP

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Definition of aroP

• Curated sequence P15993: Aromatic amino acid:H+ symporter, AroP of 457 aas and 12 TMSs (Cosgriff and Pittard 1997). Transports phenylalanine, tyrosine and tryptophan. aromatic amino acid:H⁺ symporter AroP. aromatic amino acid:H⁺ symporter AroP
• Curated sequence F2HN33: Transporter for phenylalainine, tyrosine and tryptophan of 449 aas and 12 TMSs, FywP or YsjA
• Curated sequence P24207: Phenylalanine:H+ symporter, PheP of 458 aas and 12 established TMSs. phenylalanine:H⁺ symporter PheP. phenylalanine:H⁺ symporter PheP
• Curated sequence Q2VQZ4: Arbuscular mycorrhizal fungal proline:H+ symporter, AAP1 (binds and probably transports nonpolar, hydrophobic amino acids)
• Curated sequence Q46065: Aromatic amino acid permease, AroP
• UniProt sequence A0A0C4YP23: SubName: Full=Aromatic amino acid transport protein AroP {ECO:0000313|EMBL:AJG24240.1};
• Ignore hits to A2RMP5 when looking for 'other' hits (Aromatic amino acid permease FywP)
• Comment: RR42_RS33495 from Cupriavidus basilensis FW507-4G11 (A0A0C4YP23) is the phenylalanine transporter. Ignore A2RMP5, an ortholog from another Lactococcus.

Fetched 6 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 6 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 449-536 amino acids (not heteromeric)

b0112 aromatic amino acid:H⁺ symporter AroP from Escherichia coli K-12 substr. MG1655
P15993 aromatic amino acid:H⁺ symporter AroP from Escherichia coli (strain K12)
TC 2.A.3.1.3 / P15993 Aromatic amino acid:H+ symporter, AroP of 457 aas and 12 TMSs (Cosgriff and Pittard 1997). Transports phenylalanine, tyrosine and tryptophan from Escherichia coli
PFams: AA_permease, AA_permease_2
457 amino acids: PaperBLAST, CDD, Compare to cluster

TC 2.A.3.1.22 / F2HN33 Transporter for phenylalainine, tyrosine and tryptophan of 449 aas and 12 TMSs, FywP or YsjA from Lactococcus lactis subsp. lactis (strain CV56)
PFams: AA_permease_2, AA_permease
449 amino acids: PaperBLAST, CDD, Compare to cluster

b0576 phenylalanine:H⁺ symporter PheP from Escherichia coli K-12 substr. MG1655
P24207 phenylalanine:H⁺ symporter PheP from Escherichia coli (strain K12)
TC 2.A.3.1.1 / P24207 Phenylalanine:H+ symporter, PheP of 458 aas and 12 established TMSs from Escherichia coli
PFams: AA_permease, AA_permease_2
458 amino acids: PaperBLAST, CDD, Compare to cluster

TC 2.A.3.10.22 / Q2VQZ4 Arbuscular mycorrhizal fungal proline:H+ symporter, AAP1 (binds and probably transports nonpolar, hydrophobic amino acids) from Glomus mosseae
PFams: AA_permease, AA_permease_2
536 amino acids: PaperBLAST, CDD, Compare to cluster

TC 2.A.3.1.12 / Q46065 Aromatic amino acid permease, AroP from Corynebacterium glutamicum (Brevibacterium flavum)
PFams: AA_permease_2, Spore_permease, AA_permease
463 amino acids: PaperBLAST, CDD, Compare to cluster

A0A0C4YP23 Aromatic amino acid transport protein AroP
465 amino acids: PaperBLAST, CDD, Compare to cluster