GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for atoB (acetyl-CoA C-acetyltransferase) in L-phenylalanine catabolism

Or see other characterized proteins similar to atoB

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Definition of atoB

Fetched 36 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 35 of these sequences

Found 2 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 391-427 amino acids (not heteromeric)

A4YEH9 acetyl-CoA C-acetyltransferase (EC 2.3.1.16) from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)
A4YEH9 acetyl-CoA C-acetyltransferase (EC 2.3.1.9) from Metallosphaera sedula
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
395 amino acids: PaperBLAST, CDD, Compare to cluster

B1YB71 acetyl-CoA C-acetyltransferase (EC 2.3.1.9) from Pyrobaculum neutrophilum
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
392 amino acids: PaperBLAST, CDD, Compare to cluster

B7XEI5 acetyl-CoA C-acetyltransferase (EC 2.3.1.9) from Ostrinia scapulalis
PFams: Thiolase_N, Thiolase_C
396 amino acids: PaperBLAST, CDD, Compare to cluster

D0EUY6 acetyl-CoA C-acetyltransferase (EC 2.3.1.9) from Medicago sativa
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
403 amino acids: PaperBLAST, CDD, Compare to cluster

D2IH11 acetyl-CoA C-acetyltransferase (EC 2.3.1.9) from Helianthus annuus
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
411 amino acids: PaperBLAST, CDD, Compare to cluster

P42765 3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) from Homo sapiens
THIM_HUMAN / P42765 3-ketoacyl-CoA thiolase, mitochondrial; Acetyl-CoA acetyltransferase; Acetyl-CoA acyltransferase; Acyl-CoA hydrolase, mitochondrial; Beta-ketothiolase; Mitochondrial 3-oxoacyl-CoA thiolase; T1; EC 2.3.1.16; EC 2.3.1.9; EC 3.1.2.-; EC 3.1.2.1; EC 3.1.2.2 from Homo sapiens (Human)
P42765 acetyl-CoA C-acyltransferase (EC 2.3.1.16) from Homo sapiens
PFams: Thiolase_N, Thiolase_C
397 amino acids: PaperBLAST, CDD, Compare to cluster

P45359 acetoacetyl-CoA thiolase monomer (EC 2.3.1.16) from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
P45359 acetyl-CoA C-acetyltransferase (EC 2.3.1.9) from Clostridium acetobutylicum
PFams: Thiolase_N, SpoVAD, ketoacyl-synt, Thiolase_C
392 amino acids: PaperBLAST, CDD, Compare to cluster

Q0K368 acetyl-CoA C-acetyltransferase (EC 2.3.1.9) from Cupriavidus necator
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
391 amino acids: PaperBLAST, CDD, Compare to cluster

Q0KAI3 acetyl-CoA C-acetyltransferase (EC 2.3.1.9) from Cupriavidus necator
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
392 amino acids: PaperBLAST, CDD, Compare to cluster

Q86AD9 acetyl-CoA C-acetyltransferase (EC 2.3.1.9) from Dictyostelium discoideum
PFams: Thiolase_N, Thiolase_C
414 amino acids: PaperBLAST, CDD, Compare to cluster

Q8S4Y1 acetyl-CoA C-acetyltransferase (EC 2.3.1.9) from Arabidopsis thaliana
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
403 amino acids: PaperBLAST, CDD, Compare to cluster

THIKB_MOUSE / Q8VCH0 3-ketoacyl-CoA thiolase B, peroxisomal; Acetyl-CoA acyltransferase B; Beta-ketothiolase B; Peroxisomal 3-oxoacyl-CoA thiolase B; EC 2.3.1.155; EC 2.3.1.16; EC 2.3.1.9 from Mus musculus (Mouse)
Q8VCH0 acetyl-CoA C-acyltransferase (EC 2.3.1.16) from Mus musculus
PFams: Thiolase_N, Thiolase_C
424 amino acids: PaperBLAST, CDD, Compare to cluster

Q9FIK7 acetyl-CoA C-acetyltransferase (EC 2.3.1.9) from Arabidopsis thaliana
PFams: Thiolase_N, Thiolase_C
415 amino acids: PaperBLAST, CDD, Compare to cluster

THIL_ZOORA / P07097 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Beta-ketothiolase; EC 2.3.1.9 from Zoogloea ramigera
PFams: Thiolase_N, Thiolase_C
392 amino acids: PaperBLAST, CDD, Compare to cluster

THIKB_RAT / P07871 3-ketoacyl-CoA thiolase B, peroxisomal; Acetyl-CoA acyltransferase B; Beta-ketothiolase B; Peroxisomal 3-oxoacyl-CoA thiolase B; EC 2.3.1.155; EC 2.3.1.16; EC 2.3.1.9 from Rattus norvegicus (Rat)
PFams: Thiolase_N, Thiolase_C
424 amino acids: PaperBLAST, CDD, Compare to cluster

THIM_RAT / P13437 3-ketoacyl-CoA thiolase, mitochondrial; Acetyl-CoA acetyltransferase; Acetyl-CoA acyltransferase; Acyl-CoA hydrolase, mitochondrial; Beta-ketothiolase; Mitochondrial 3-oxoacyl-CoA thiolase; EC 2.3.1.16; EC 2.3.1.9; EC 3.1.2.-; EC 3.1.2.1; EC 3.1.2.2 from Rattus norvegicus (Rat)
PFams: Thiolase_N, Thiolase_C
397 amino acids: PaperBLAST, CDD, Compare to cluster

P14611 acetyl-CoA acetyltransferase subunit (EC 2.3.1.16) from Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)
THIL_CUPNH / P14611 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Beta-ketothiolase; EC 2.3.1.9 from Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
393 amino acids: PaperBLAST, CDD, Compare to cluster

P24752 acetyl-CoA acetyltransferase monomer (EC 2.3.1.16) from Homo sapiens
THIL_HUMAN / P24752 Acetyl-CoA acetyltransferase, mitochondrial; Acetoacetyl-CoA thiolase; T2; EC 2.3.1.9 from Homo sapiens (Human)
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
427 amino acids: PaperBLAST, CDD, Compare to cluster

P41338 Erg10 (EC 2.3.1.16) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
THIL_YEAST / P41338 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Ergosterol biosynthesis protein 10; EC 2.3.1.9 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
398 amino acids: PaperBLAST, CDD, Compare to cluster

THIL_THIVI / P45363 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Beta-ketothiolase; EC 2.3.1.9 from Thiocystis violacea
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
394 amino acids: PaperBLAST, CDD, Compare to cluster

THIL_ALLVD / P45369 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Beta-ketothiolase; EC 2.3.1.9 from Allochromatium vinosum (strain ATCC 17899 / DSM 180 / NBRC 103801 / NCIMB 10441 / D) (Chromatium vinosum)
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
394 amino acids: PaperBLAST, CDD, Compare to cluster

THL_BACSU / P45855 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; EC 2.3.1.9 from Bacillus subtilis (strain 168)
PFams: Thiolase_N, Thiolase_C
393 amino acids: PaperBLAST, CDD, Compare to cluster

SMc03879 Acetyl-CoA acetyltransferase (EC 2.3.1.9) from Sinorhizobium meliloti 1021
THIL_RHIME / P50174 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Beta-ketothiolase; EC 2.3.1.9 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
PFams: Thiolase_N, Thiolase_C
393 amino acids: PaperBLAST, CDD, Compare to cluster

THIL_SYNY3 / P73825 Acetyl-CoA acetyltransferase; Beta-ketothiolase PhaA; EC 2.3.1.9 from Synechocystis sp. (strain PCC 6803 / Kazusa)
PFams: Thiolase_N, Thiolase_C
396 amino acids: PaperBLAST, CDD, Compare to cluster

THLA_SYNWW / Q0AVM3 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; EC 2.3.1.9 from Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen)
PFams: Thiolase_N, Thiolase_C
396 amino acids: PaperBLAST, CDD, Compare to cluster

Q0KBP1 β-ketothiolase (EC 2.3.1.16) from Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)
BKTB_CUPNH / Q0KBP1 Beta-ketothiolase BktB; Acetyl-CoA acetyltransferase; Acetyl-CoA acyltransferase; EC 2.3.1.16; EC 2.3.1.9 from Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
394 amino acids: PaperBLAST, CDD, Compare to cluster

Q9BWD1 acetyl-CoA acetyltransferase (EC 2.3.1.16) from Homo sapiens
THIC_HUMAN / Q9BWD1 Acetyl-CoA acetyltransferase, cytosolic; Acetyl-CoA transferase-like protein; Cytosolic acetoacetyl-CoA thiolase; EC 2.3.1.9 from Homo sapiens (Human)
PFams: Thiolase_N, Thiolase_C
397 amino acids: PaperBLAST, CDD, Compare to cluster

THIL_SCHPO / Q9UQW6 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Ergosterol biosynthesis protein 10; EC 2.3.1.9 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
PFams: Thiolase_N, Thiolase_C
395 amino acids: PaperBLAST, CDD, Compare to cluster

b2224 acetyl-CoA acetyltransferase (EC 2.3.1.16; EC 2.3.1.9) from Escherichia coli K-12 substr. MG1655
P76461 acetyl-CoA acetyltransferase (EC 2.3.1.16) from Escherichia coli (strain K12)
PFams: Thiolase_N, Thiolase_C
394 amino acids: PaperBLAST, CDD, Compare to cluster

PGA1_c03400 acetyl-CoA:acetyl-CoA C-acetyltransferase / acetyl-CoA:propanoyl-CoA 2-C-acetyltransferase (EC 2.3.1.9; EC 2.3.1.16) from Phaeobacter inhibens BS107
PFams: Thiolase_N, Thiolase_C
391 amino acids: PaperBLAST, CDD, Compare to cluster

PfGW456L13_2411 Acetyl-CoA C-acetyltransferase (EC 2.3.1.9) from Pseudomonas fluorescens GW456-L13
PFams: Thiolase_N, Thiolase_C
393 amino acids: PaperBLAST, CDD, Compare to cluster

AO353_25685 acetyl-CoA:acetyl-CoA C-acetyltransferase / acetyl-CoA:propanoyl-CoA 2-C-acetyltransferase (EC 2.3.1.9; EC 2.3.1.16) from Pseudomonas fluorescens FW300-N2E3
PFams: Thiolase_N, Thiolase_C
397 amino acids: PaperBLAST, CDD, Compare to cluster

AO356_21640 acetyl-CoA C-acetyltransferase [EC: 2.3.1.9] from Pseudomonas fluorescens FW300-N2C3
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
393 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 383-383 amino acids (heteromeric)

I3R3D1 acetyl-CoA C-acetyltransferase (subunit 2/2) (EC 2.3.1.9) from Haloferax mediterranei
PFams: Thiolase_N, Thiolase_C
Heteromeric, 383 amino acids: PaperBLAST, CDD, Compare to cluster

I3RA72 acetyl-CoA C-acetyltransferase (subunit 2/2) (EC 2.3.1.9) from Haloferax mediterranei
PFams: Thiolase_N, Thiolase_C
Heteromeric, 383 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/1 heteromeric)

G7YHN5 acetyl-CoA C-acetyltransferase (EC 2.3.1.9) from Clonorchis sinensis
PFams: Thiolase_N, Thiolase_C
284 amino acids: PaperBLAST, CDD