Other Characterized Proteins Similar to SLC6A7

GapMind for catabolism of small carbon sources

Other Characterized Proteins Similar to SLC6A7

Finding the characterized proteins for SLC6A7 (proline:Na+ symporter) in L-proline catabolism

Or see clustering for step SLC6A7

Or see all steps for L-proline catabolism

Or cluster curated proteins matching a keyword

Definition of SLC6A7

Curated sequence CH_091144: sodium-dependent proline transporter. Proline:Na+ symporter
Curated sequence Q64093: Sodium- and chloride-dependent transporter XTRP3; Sodium/imino-acid transporter 1; Solute carrier family 6 member 20; Transporter rB21A. sodium- and chloride-dependent transporter XTRP3. Na+/Amino acid transporter 1, SIT1/IMINO (SLC6A20). Transports imino acids such as proline (Km=0.2 mM), pipecolate, and N-methylated amino acids such as MeAIB and sarcosine (Na+-dependent, Cl--stimulated, pH-independent, voltage-dependent) (Li+, but not H+ can substitute for Na+) (Takanaga et al., 2005). It is a 2Na+/1Cl--proline cotransporter
Curated sequence P48065: Betaine/GABA:Na+ symporter, BGT1. (Substrates include: betaine, GABA, diaminobutyrate, β-alanine, proline, quinidine, dimethylglycine, glycine, and sarcosine with decreasing affinity in that order)
Curated sequence Q99884: Sodium-dependent proline transporter (Solute carrier family 6 member 7)

Fetched 4 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 64 other characterized sequences. (Found 68 hits including self hits.)

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for SLC6A7.)

S620A_MOUSE / Q8VDB9 Sodium- and chloride-dependent transporter XTRP3A; IMINO-B; Solute carrier family 6 member 20A; X transporter protein 3 similar 1 from Mus musculus (Mouse)
PFams: SNF
592 amino acids: PaperBLAST, CDD, SwissProt::Q8VDB9
96% identical to

S6A20_RAT / Q64093 Sodium- and chloride-dependent transporter XTRP3; Sodium/imino-acid transporter 1; Solute carrier family 6 member 20; Transporter rB21A from Rattus norvegicus (Rat)
TC 2.A.22.6.1 / Q64093 Na+/Amino acid transporter 1, SIT1/IMINO (SLC6A20). Transports imino acids such as proline (Km=0.2 mM), pipecolate, and N-methylated amino acids such as MeAIB and sarcosine (Na+-dependent, Cl--stimulated, pH-independent, voltage-dependent) (Li+, but not H+ can substitute for Na+) (Takanaga et al., 2005). It is a 2Na+/1Cl--proline cotransporter from Rattus norvegicus (Rat)
RF|NP_579830.1 sodium- and chloride-dependent transporter XTRP3 from Rattus norvegicus
PFams: SNF
616 amino acids: PaperBLAST, CDD

S6A12_CANLF / P27799 Sodium- and chloride-dependent betaine transporter; Na(+)/Cl(-) betaine/GABA transporter; Solute carrier family 6 member 12 from Canis lupus familiaris (Dog) (Canis familiaris)
PFams: SNF
614 amino acids: PaperBLAST, CDD, SwissProt::P27799
91% identical to

TC 2.A.22.3.1 / P48065 Betaine/GABA:Na+ symporter, BGT1. (Substrates include: betaine, GABA, diaminobutyrate, β-alanine, proline, quinidine, dimethylglycine, glycine, and sarcosine with decreasing affinity in that order) from Homo sapiens (Human)
PFams: SNF
614 amino acids: PaperBLAST, CDD

S6A20_HUMAN / Q9NP91 Sodium- and chloride-dependent transporter XTRP3; Sodium/imino-acid transporter 1; Solute carrier family 6 member 20; Transporter rB21A homolog from Homo sapiens (Human)
TC 2.A.22.6.8 / Q9NP91 Sodium- and chloride-dependent transporter XTRP3 (Sodium/amino-acid transporter 1) (Solute carrier family 6 member 20) (Transporter rB21A homologue) from Homo sapiens
PFams: SNF
592 amino acids: PaperBLAST, CDD, SwissProt::Q9NP91
90% identical to

S620B_MOUSE / O88575 Sodium- and chloride-dependent transporter XTRP3B; IMINO-K; Solute carrier family 6 member 20B from Mus musculus (Mouse)
PFams: SNF
635 amino acids: PaperBLAST, CDD, SwissProt::O88575
88% identical to

S6A13_HUMAN / Q9NSD5 Sodium- and chloride-dependent GABA transporter 2; GAT-2; Solute carrier family 6 member 13 from Homo sapiens (Human)
TC 2.A.22.3.10 / Q9NSD5 Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13) from Homo sapiens
PFams: SNF
602 amino acids: PaperBLAST, CDD, SwissProt::Q9NSD5
70% identical to

S6A13_RAT / P31646 Sodium- and chloride-dependent GABA transporter 2; GAT-2; Solute carrier family 6 member 13 from Rattus norvegicus (Rat)
PFams: SNF
602 amino acids: PaperBLAST, CDD, SwissProt::P31646
71% identical to

S6A13_MOUSE / P31649 Sodium- and chloride-dependent GABA transporter 2; GAT-2; Sodium- and chloride-dependent GABA transporter 3; GAT-3; Solute carrier family 6 member 13 from Mus musculus (Mouse)
TC 2.A.22.3.8 / P31649 Mouse GABA, β-alanine, fluoro-β-alanine and taurine transporter-3 (GAT3) (Liu et al. 1999). Orthologous to rat and human GAT2; 72% identical to GAT4 (2.A.22.3.7) (takes up GABA with high affinity into presynaptic terminals). Also takes up the carnitine precursor, gamma-butyrobetaine from Mus musculus
PFams: SNF
602 amino acids: PaperBLAST, CDD, SwissProt::P31649
72% identical to

TC 2.A.22.3.7 / Q8BWA7 The GABA transporter, GAT4 (single mutations render this transporter C1- independent) from Mus musculus
PFams: SNF
627 amino acids: PaperBLAST, CDD, TCDB::Q8BWA7
67% identical to

TC 2.A.22.3.9 / P48066 Sodium- and chloride-dependent GABA transporter 3 (GAT-3) (Solute carrier family 6 member 11). Expression of GAT-3 was selectively decreased within the amygdala of alcohol-choosing rats, and a knockdown of this transcript reversed choice preference of rats that originally chose a sweet solution over alcohol. GAT-3 expression was selectively decreased in the central amygdala of alcohol-dependent people as well. Thus, impaired GABA clearance within the amygdala contributes to alcohol addiction from Homo sapiens
PFams: SNF
632 amino acids: PaperBLAST, CDD, TCDB::P48066
67% identical to

SC6A6_CANLF / Q00589 Sodium- and chloride-dependent taurine transporter; Solute carrier family 6 member 6 from Canis lupus familiaris (Dog) (Canis familiaris)
PFams: SNF
620 amino acids: PaperBLAST, CDD, SwissProt::Q00589
64% identical to

SC6A6_HUMAN / P31641 Sodium- and chloride-dependent taurine transporter; Solute carrier family 6 member 6 from Homo sapiens (Human)
TC 2.A.22.3.3 / P31641 The taurine:Na+ symporter, TauT or SLC6A6 (also transports β-alanine and γ-aminobutyric acid (GABA); Tomi et al., 2008; Anderson et al., 2009). Biallelic mutation of TauT is linked to early retinal degeneration (Preising et al. 2019). Oral taurine administration of retinal degeneration and cardiomyopathy reverses the phenotype from Homo sapiens (Human)
PFams: SNF
620 amino acids: PaperBLAST, CDD, SwissProt::P31641
64% identical to

SC6A6_RAT / P31643 Sodium- and chloride-dependent taurine transporter; Solute carrier family 6 member 6 from Rattus norvegicus (Rat)
PFams: SNF
621 amino acids: PaperBLAST, CDD, SwissProt::P31643
63% identical to

SC6A6_MOUSE / O35316 Sodium- and chloride-dependent taurine transporter; Solute carrier family 6 member 6 from Mus musculus (Mouse)
PFams: SNF
621 amino acids: PaperBLAST, CDD, SwissProt::O35316
63% identical to

TC 2.A.22.3.5 / P28570 Renal apical membrane creatine:Na2+:Cl- symporter (CRT) from Rattus norvegicus (Rat)
PFams: SNF
635 amino acids: PaperBLAST, CDD, TCDB::P28570
56% identical to

SC6A8_HUMAN / P48029 Sodium- and chloride-dependent creatine transporter 1; CT1; Creatine transporter 1; Solute carrier family 6 member 8 from Homo sapiens (Human)
TC 2.A.22.3.11 / P48029 Sodium- and chloride-dependent creatine transporter 1 (CT1 or CreaT) (Creatine transporter 1) (Solute carrier family 6 member 8, SLC6A8) from Homo sapiens
PFams: SNF
635 amino acids: PaperBLAST, CDD, SwissProt::P48029
56% identical to

TC 2.A.22.3.4 / P31661 Creatine:Na+ symporter from Oryctolagus cuniculus (Rabbit)
PFams: SNF
635 amino acids: PaperBLAST, CDD, TCDB::P31661
56% identical to

SC6A1_RAT / P23978 Sodium- and chloride-dependent GABA transporter 1; GAT-1; Solute carrier family 6 member 1 from Rattus norvegicus (Rat)
SC6A1_MOUSE / P31648 Sodium- and chloride-dependent GABA transporter 1; GAT-1; Solute carrier family 6 member 1 from Mus musculus (Mouse)
PFams: SNF
599 amino acids: PaperBLAST, CDD, SwissProt::P23978
50% identical to

SC6A1_HUMAN / P30531 Sodium- and chloride-dependent GABA transporter 1; GAT-1; Solute carrier family 6 member 1 from Homo sapiens (Human)
TC 2.A.22.3.2 / P30531 γ-aminobutyric acid (GABA):Na+:Cl- symporter, GAT-1 (Stoichiometry, GABA:Na+ = 1:2 where both Na+ binding sites, Na1 and Na2, have been identified. Na2 but not Na1 can accommodate Li+ (Zhou et al., 2006)). Cai et al. 2005 have reported that N-glycosylation increases the stability, trafficking and GABA-uptake of GABA transporter 1. Glutamine 291 is essential for Cl- binding (Ben-Yona et al., 2011). Four human isoforms have been identified, GAT-1, GAT-2, GAT-3, and GAT-4, all about 70% identical to each other (Borden et al., 1992). GAT-2 transports γ-aminobutyric acid and β-alanine (Christiansen et al, 2007) It also concentratively takes up β-alanine and α-fluoro-β-alanine (Liu et al., 1999). GAT1 is capable of intracellular Na+-, Cl-- and GABA-induced outward currents (reverse GABA transport; GABA efflux) from Homo sapiens (Human)
PFams: SNF
599 amino acids: PaperBLAST, CDD, SwissProt::P30531
49% identical to

SC6A5_HUMAN / Q9Y345 Sodium- and chloride-dependent glycine transporter 2; GlyT-2; GlyT2; Solute carrier family 6 member 5 from Homo sapiens (Human)
TC 2.A.22.2.10 / Q9Y345 Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5) from Homo sapiens
PFams: SNF
797 amino acids: PaperBLAST, CDD, SwissProt::Q9Y345
51% identical to

TC 2.A.22.2.11 / Q99884 Sodium-dependent proline transporter (Solute carrier family 6 member 7) from Homo sapiens
PFams: SNF
636 amino acids: PaperBLAST, CDD

SC6A5_MOUSE / Q761V0 Sodium- and chloride-dependent glycine transporter 2; GlyT-2; GlyT2; Solute carrier family 6 member 5 from Mus musculus (Mouse)
TC 2.A.22.2.6 / Q761V0 Glycine:Na+ transporter, GlyT2b (glycine/3Na+/1Cl- symporter, SLC6A5)
PFams: SNF
799 amino acids: PaperBLAST, CDD, SwissProt::Q761V0
51% identical to

TC 2.A.22.2.11 / Q99884 Sodium-dependent proline transporter (Solute carrier family 6 member 7) from Homo sapiens
PFams: SNF
636 amino acids: PaperBLAST, CDD

SC6A9_HUMAN / P48067 Sodium- and chloride-dependent glycine transporter 1; GlyT-1; GlyT1; Solute carrier family 6 member 9 from Homo sapiens (Human)
TC 2.A.22.2.12 / P48067 Sodium- and chloride-dependent glycine transporter 1 (GlyT-1) (GlyT1) (Solute carrier family 6 member 9) from Homo sapiens
PFams: SNF
706 amino acids: PaperBLAST, CDD, SwissProt::P48067
52% identical to

TC 2.A.22.2.1 / P28573 Proline:Na+ symporter from Rattus norvegicus (Rat)
RF|NP_446448.2 sodium-dependent proline transporter from Rattus norvegicus
PFams: SNF
637 amino acids: PaperBLAST, CDD

SC6A5_RAT / P58295 Sodium- and chloride-dependent glycine transporter 2; GlyT-2; GlyT2; Solute carrier family 6 member 5 from Rattus norvegicus (Rat)
PFams: SNF
799 amino acids: PaperBLAST, CDD, SwissProt::P58295
50% identical to

TC 2.A.22.2.11 / Q99884 Sodium-dependent proline transporter (Solute carrier family 6 member 7) from Homo sapiens
PFams: SNF
636 amino acids: PaperBLAST, CDD

S6A19_MOUSE / Q9D687 Sodium-dependent neutral amino acid transporter B(0)AT1; Solute carrier family 6 member 19; System B(0) neutral amino acid transporter AT1 from Mus musculus (Mouse)
TC 2.A.22.6.3 / Q9D687 Sodium-dependent neutral amino acid transporter B(0) aka B0at1, component of B(O)AT1 or BOAT (SKC6A19;Hartnup's disease protein is a kidney and intestinal apical membrane epithelial transporter for Na+-dependent, Cl--independent reabsorption of neutral amino acids. Many neutral L-amino acids bind with ~0.5 mM affinities; Leu is the preferred substrate, but all large, neutral, non-aromatic, L-amino acids bind to this transporter. Uptake of leucine is sodium-dependent. In contrast to other members of the neurotransmitter transporter family, this one does not appear to be chloride-dependent from Mus musculus (Mouse)
RF|NP_083154.1 sodium-dependent neutral amino acid transporter B(0) from Mus musculus
PFams: SNF
Heteromeric, 634 amino acids: PaperBLAST, CDD, CharProtDB::CH_091612
46% identical to

TC 2.A.22.6.4 / Q96N87 The neutral amino acid transporter, B0AT3 (Slc6a18); XT2 (55% identical to 2.A.22.6.3) from Homo sapiens
PFams: SNF
628 amino acids: PaperBLAST, CDD, TCDB::Q96N87
47% identical to

SC6A9_RAT / P28572 Sodium- and chloride-dependent glycine transporter 1; GlyT-1; GlyT1; Solute carrier family 6 member 9 from Rattus norvegicus (Rat)
TC 2.A.22.2.2 / P28572 Glycine:Na+ symporter, GlyT1c (glycine/2Na+/1Cl- symporter) from Rattus norvegicus (Rat)
PFams: SNF
638 amino acids: PaperBLAST, CDD, SwissProt::P28572
49% identical to

S6A19_RAT / Q2A865 Sodium-dependent neutral amino acid transporter B(0)AT1; Solute carrier family 6 member 19; System B(0) neutral amino acid transporter AT1 from Rattus norvegicus (Rat)
PFams: SNF
634 amino acids: PaperBLAST, CDD, SwissProt::Q2A865
46% identical to

S6A18_HUMAN / Q96N87 Inactive sodium-dependent neutral amino acid transporter B(0)AT3; Sodium- and chloride-dependent transporter XTRP2; Solute carrier family 6 member 18; System B(0) neutral amino acid transporter AT3 from Homo sapiens (Human)
PFams: SNF
628 amino acids: PaperBLAST, CDD, SwissProt::Q96N87
47% identical to

SC6A9_MOUSE / P28571 Sodium- and chloride-dependent glycine transporter 1; GlyT-1; GlyT1; Solute carrier family 6 member 9 from Mus musculus (Mouse)
PFams: SNF
692 amino acids: PaperBLAST, CDD, SwissProt::P28571
51% identical to

TC 2.A.22.6.9 / R4N225 Sea bass amino acid uptake porter, SLC6A19 or B0AT1 of 634 aas from Dicentrarchus labrax
PFams: SNF
634 amino acids: PaperBLAST, CDD, TCDB::R4N225
46% identical to

RF|NP_446270.1 sodium- and chloride-dependent glycine transporter 1 from Rattus norvegicus
PFams: SNF
633 amino acids: PaperBLAST, CDD, CharProtDB::CH_091712
50% identical to

S6A18_MOUSE / O88576 Sodium-dependent neutral amino acid transporter B(0)AT3; Sodium- and chloride-dependent transporter XTRP2; Solute carrier family 6 member 18; System B(0) neutral amino acid transporter AT3 from Mus musculus (Mouse)
PFams: SNF
615 amino acids: PaperBLAST, CDD, SwissProt::O88576
47% identical to

S6A18_RAT / Q62687 Sodium-dependent neutral amino acid transporter B(0)AT3; Renal osmotic stress-induced Na-Cl organic solute cotransporter; ROSIT; Sodium- and chloride-dependent transporter XTRP2; Solute carrier family 6 member 18; System B(0) neutral amino acid transporter AT3 from Rattus norvegicus (Rat)
PFams: SNF
615 amino acids: PaperBLAST, CDD, SwissProt::Q62687
47% identical to

S6A19_HUMAN / Q695T7 Sodium-dependent neutral amino acid transporter B(0)AT1; Solute carrier family 6 member 19; System B(0) neutral amino acid transporter AT1 from Homo sapiens (Human)
TC 2.A.22.6.3 / Q695T7 Sodium-dependent neutral amino acid transporter B(0), component of B(O)AT1 or BOAT (SKC6A19;Hartnup's disease protein is a kidney and intestinal apical membrane epithelial transporter for Na+-dependent, Cl--independent reabsorption of neutral amino acids. Many neutral L-amino acids bind with ~0.5 mM affinities; Leu is the preferred substrate, but all large, neutral, non-aromatic, L-amino acids bind to this transporter. Uptake of leucine is sodium-dependent. In contrast to other members of the neurotransmitter transporter family, this one does not appear to be chloride-dependent from Homo sapiens (Human)
PFams: SNF
Heteromeric, 634 amino acids: PaperBLAST, CDD, SwissProt::Q695T7
44% identical to

SC6A9_XENLA / A7Y2W8 Sodium- and chloride-dependent glycine transporter 1; GlyT-1; GlyT1; xGlyT1; Solute carrier family 6 member 9 from Xenopus laevis (African clawed frog)
PFams: SNF
633 amino acids: PaperBLAST, CDD, SwissProt::A7Y2W8
50% identical to

TC 2.A.22.2.11 / Q99884 Sodium-dependent proline transporter (Solute carrier family 6 member 7) from Homo sapiens
PFams: SNF
636 amino acids: PaperBLAST, CDD

S6A17_HUMAN / Q9H1V8 Sodium-dependent neutral amino acid transporter SLC6A17; Sodium-dependent neurotransmitter transporter NTT4; Solute carrier family 6 member 17 from Homo sapiens (Human)
TC 2.A.22.6.6 / Q9H1V8 Sodium-dependent vesicular neutral amino acid transporter SLC6A17 (Sodium-dependent neurotransmitter transporter NTT4/BOAT3) (Solute carrier family 6 member 17) from Homo sapiens
PFams: SNF
727 amino acids: PaperBLAST, CDD, SwissProt::Q9H1V8
43% identical to

S6A14_MOUSE / Q9JMA9 Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+); Amino acid transporter ATB0+; Colonic system B0+ amino acid transporter CATB0+; Solute carrier family 6 member 14 from Mus musculus (Mouse)
PFams: SNF
638 amino acids: PaperBLAST, CDD, SwissProt::Q9JMA9
47% identical to

S6A17_MOUSE / Q8BJI1 Sodium-dependent neutral amino acid transporter SLC6A17; Sodium-dependent neurotransmitter transporter NTT4; Solute carrier family 6 member 17 from Mus musculus (Mouse)
PFams: SNF
727 amino acids: PaperBLAST, CDD, SwissProt::Q8BJI1
43% identical to

SC6A2_HUMAN / P23975 Sodium-dependent noradrenaline transporter; Norepinephrine transporter; NET; Solute carrier family 6 member 2 from Homo sapiens (Human)
TC 2.A.22.1.2 / P23975 Noradrenaline (norepinephrine):Na+ symporter (NET1, NAT1, SLC6?A2) (also transports 1-methyl-4-tetrahydropyridinium and amphetamines; it is a target of cocaine and amphetamines as well as of therapetics for depression, obsessive-compulsive disorders, and post-traumatic stress disorder. This homooligomeric transporter binds one substrate molecule per transporter subunit (Schwartz et al., 2005; Schlessinger et al., 2011; Andersen et al., 2011). Extracellular loop 3 contributes to substrate and inhibitor selectivity (Lynagh et al. 2013). The highly conserved MELAL and GQXXRXG motifs, located in the second transmembrane domain and the first intracellular loop of hNET, respectively, are determinants of NET cell surface expression, and substrate and inhibitor binding (Sucic and Bryan-Lluka 2007). Based on modeling, the high affinity substrate binding site (S1) of the human norepinephrine transporter has been predicted and then verified by mutational studies from Homo sapiens (Human)
RF|NP_001034.1 sodium-dependent noradrenaline transporter from Homo sapiens
PFams: SNF
617 amino acids: PaperBLAST, CDD, CharProtDB::CH_091352
46% identical to

TC 2.A.22.1.5 / Q95VZ4 High affinity octopamine transporter, OAT (also transports tyramine and dopamine in the 0.4-3.0 μM range (Donly et al., 2007)) from Trichoplusia ni
PFams: SNF
744 amino acids: PaperBLAST, CDD, TCDB::Q95VZ4
46% identical to

SC6A5_XENLA / A7Y2X0 Sodium- and chloride-dependent glycine transporter 2; GlyT-2; GlyT2; xGlyT2; Solute carrier family 6 member 5 from Xenopus laevis (African clawed frog)
PFams: SNF
790 amino acids: PaperBLAST, CDD, SwissProt::A7Y2X0
46% identical to

TC 2.A.22.2.11 / Q99884 Sodium-dependent proline transporter (Solute carrier family 6 member 7) from Homo sapiens
PFams: SNF
636 amino acids: PaperBLAST, CDD

S6A15_HUMAN / Q9H2J7 Sodium-dependent neutral amino acid transporter B(0)AT2; Sodium- and chloride-dependent neurotransmitter transporter NTT73; Sodium-coupled branched-chain amino-acid transporter 1; Solute carrier family 6 member 15; Transporter v7-3 from Homo sapiens (Human)
TC 2.A.22.6.7 / Q9H2J7 Sodium-dependent neutral amino acid transporter B(0)AT2 (Sodium- and chloride-dependent neurotransmitter transporter NTT73) (Sodium-coupled branched-chain amino-acid transporter 1) (Solute carrier family 6 member 15) (Transporter v7-3) from Homo sapiens
PFams: SNF
730 amino acids: PaperBLAST, CDD, SwissProt::Q9H2J7
44% identical to

SC6A3_BOVIN / P27922 Sodium-dependent dopamine transporter; DA transporter; DAT; Solute carrier family 6 member 3 from Bos taurus (Bovine)
PFams: SNF
693 amino acids: PaperBLAST, CDD, SwissProt::P27922
42% identical to

SC6A3_MOUSE / Q61327 Sodium-dependent dopamine transporter; DA transporter; DAT; Solute carrier family 6 member 3 from Mus musculus (Mouse)
PFams: SNF
619 amino acids: PaperBLAST, CDD, SwissProt::Q61327
45% identical to

TC 2.A.22.2.11 / Q99884 Sodium-dependent proline transporter (Solute carrier family 6 member 7) from Homo sapiens
PFams: SNF
636 amino acids: PaperBLAST, CDD

SC6A2_BOVIN / P51143 Sodium-dependent noradrenaline transporter; Norepinephrine transporter; NET; Solute carrier family 6 member 2 from Bos taurus (Bovine)
PFams: SNF
615 amino acids: PaperBLAST, CDD, SwissProt::P51143
45% identical to

S6A17_RAT / P31662 Sodium-dependent neutral amino acid transporter SLC6A17; Sodium-dependent neurotransmitter transporter NTT4; Solute carrier family 6 member 17 from Rattus norvegicus (Rat)
TC 2.A.22.6.2 / P31662 Synaptic vesicle neutral amino acid:Na+ symporter NTT4/XT1/BOAT3 (SLC6A17) (catalyzes uptake of neurotransmitters into presynaptic vesicles from Rattus norvegicus (Rat)
PFams: SNF
727 amino acids: PaperBLAST, CDD, SwissProt::P31662
43% identical to

S6A14_HUMAN / Q9UN76 Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+); Amino acid transporter ATB0+; Solute carrier family 6 member 14 from Homo sapiens (Human)
TC 2.A.22.2.3 / Q9UN76 Neutral and cationic amino acid:Na+:Cl- symporter, B0+. The rat homologue (NP_001032633) transports basic and zwitterionic amino acids, but not proline, aspartic acid and glutamic acid (Uchiyama et al, 2008) from Homo sapiens (Human)
RF|NP_009162.1 sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) from Homo sapiens
PFams: SNF
642 amino acids: PaperBLAST, CDD, CharProtDB::CH_091317
45% identical to

TC 2.A.22.2.11 / Q99884 Sodium-dependent proline transporter (Solute carrier family 6 member 7) from Homo sapiens
PFams: SNF
636 amino acids: PaperBLAST, CDD

S6A15_MOUSE / Q8BG16 Sodium-dependent neutral amino acid transporter B(0)AT2; Sodium- and chloride-dependent neurotransmitter transporter NTT73; Solute carrier family 6 member 15; Transporter v7-3 from Mus musculus (Mouse)
PFams: SNF
729 amino acids: PaperBLAST, CDD, SwissProt::Q8BG16
43% identical to

SC6A3_HUMAN / Q01959 Sodium-dependent dopamine transporter; DA transporter; DAT; Solute carrier family 6 member 3 from Homo sapiens (Human)
TC 2.A.22.1.3 / Q01959 Dopamine:Na+ symporter, DAT (also takes up amphetamines in symport with Na+ which promotes intracellular Na+-dependent dopamine efflux (Khoshbouei et al., 2003)). It is inhibited by cocaine, amphetamines, neurotoxins, antidepressants and ethanol (Chen et al., 2004)]. Zn2+ potentiates uncoupled Cl- conductance from Homo sapiens (Human)
GB|ABO77644.1 sodium-dependent dopamine transporter from Homo sapiens
PFams: SNF
620 amino acids: PaperBLAST, CDD, CharProtDB::CH_091026
45% identical to

TC 2.A.22.2.11 / Q99884 Sodium-dependent proline transporter (Solute carrier family 6 member 7) from Homo sapiens
PFams: SNF
636 amino acids: PaperBLAST, CDD

SC6A3_RAT / P23977 Sodium-dependent dopamine transporter; DA transporter; DAT; Solute carrier family 6 member 3 from Rattus norvegicus (Rat)
PFams: SNF
619 amino acids: PaperBLAST, CDD, SwissProt::P23977
44% identical to

S6A15_RAT / Q08469 Sodium-dependent neutral amino acid transporter B(0)AT2; Solute carrier family 6 member 15; Transporter v7-3; sodium- and chloride-dependent neurotransmitter transporter NTT73 from Rattus norvegicus (Rat)
PFams: SNF
729 amino acids: PaperBLAST, CDD, SwissProt::Q08469
43% identical to

SC6A4_MACMU / Q9MYX0 Sodium-dependent serotonin transporter; SERT; 5HT transporter; 5HTT; Solute carrier family 6 member 4 from Macaca mulatta (Rhesus macaque)
PFams: 5HT_transport_N, SNF
630 amino acids: PaperBLAST, CDD, SwissProt::Q9MYX0
44% identical to

SC6A4_MOUSE / Q60857 Sodium-dependent serotonin transporter; SERT; 5HT transporter; 5HTT; Solute carrier family 6 member 4 from Mus musculus (Mouse)
PFams: 5HT_transport_N, SNF
630 amino acids: PaperBLAST, CDD, SwissProt::Q60857
44% identical to

SC6A4_HUMAN / P31645 Sodium-dependent serotonin transporter; SERT; 5HT transporter; 5HTT; Solute carrier family 6 member 4 from Homo sapiens (Human)
TC 2.A.22.1.1 / P31645 Serotonin (5-hydroxytryptamine; 5 HT):Na+:Cl- symporter, SERT-A from Homo sapiens (Human)
GB|AAW80933.1 sodium-dependent serotonin transporter from Homo sapiens
PFams: 5HT_transport_N, SNF
630 amino acids: PaperBLAST, CDD, CharProtDB::CH_090996
44% identical to

SC6A4_RAT / P31652 Sodium-dependent serotonin transporter; SERT; 5HT transporter; 5HTT; Solute carrier family 6 member 4 from Rattus norvegicus (Rat)
PFams: 5HT_transport_N, SNF
630 amino acids: PaperBLAST, CDD, SwissProt::P31652
44% identical to

DAT_DROME / Q7K4Y6 Sodium-dependent dopamine transporter; Protein fumin from Drosophila melanogaster (Fruit fly)
TC 2.A.22.1.7 / Q7K4Y6 Dopamine transporter from Drosophila melanogaster
PFams: SNF
631 amino acids: PaperBLAST, CDD, SwissProt::Q7K4Y6
44% identical to

TC 2.A.22.2.11 / Q99884 Sodium-dependent proline transporter (Solute carrier family 6 member 7) from Homo sapiens
PFams: SNF
636 amino acids: PaperBLAST, CDD

SC6A4_BOVIN / Q9XT49 Sodium-dependent serotonin transporter; SERT; 5HT transporter; 5HTT; Solute carrier family 6 member 4 from Bos taurus (Bovine)
PFams: 5HT_transport_N, SNF
630 amino acids: PaperBLAST, CDD, SwissProt::Q9XT49
43% identical to

SNF3_CAEEL / G5EBN9 Sodium- and chloride-dependent betaine transporter; Betaine transporter SNF-3; Na(+)/Cl(-) betaine/GABA transporter; Sodium:neurotransmitter symporter family protein 3 from Caenorhabditis elegans
PFams: SNF
600 amino acids: PaperBLAST, CDD, SwissProt::G5EBN9
41% identical to

INE_DROME / Q9VR07 Sodium- and chloride-dependent GABA transporter ine; Protein inebriated; Protein receptor oscillation A from Drosophila melanogaster (Fruit fly)
TC 2.A.22.3.12 / Q9VR07 Sodium- and chloride-dependent GABA transporter, Ine (Protein inebriated) (Protein receptor oscillation A) from Drosophila melanogaster
PFams: SNF
943 amino acids: PaperBLAST, CDD, SwissProt::Q9VR07
42% identical to

SC6A4_CAVPO / O35899 Sodium-dependent serotonin transporter; SERT; 5HT transporter; 5HTT; Solute carrier family 6 member 4 from Cavia porcellus (Guinea pig)
PFams: 5HT_transport_N, SNF
630 amino acids: PaperBLAST, CDD, SwissProt::O35899
42% identical to

SC6A4_DROME / P51905 Sodium-dependent serotonin transporter; 5HT transporter; 5HTT; Cocaine-sensitive serotonin transporter; dSERT1 from Drosophila melanogaster (Fruit fly)
TC 2.A.22.1.9 / P51905 The sodium-dependent serotonin transporter of 622 aas and 12 TMSs, SERT or SerT from Drosophila melanogaster
PFams: SNF
622 amino acids: PaperBLAST, CDD, SwissProt::P51905
43% identical to

TC 2.A.22.1.6 / E9LD23 The dopamine/norepinephrine transporter (SmDAT) from Schistosoma mansoni
PFams: SNF
727 amino acids: PaperBLAST, CDD, TCDB::E9LD23
41% identical to

TC 2.A.22.1.10 / Q963F3 Serotonin transporter, Mod-5, of 671 aas and 12 TMSs from Caenorhabditis elegans
PFams: SNF
671 amino acids: PaperBLAST, CDD, TCDB::Q963F3
41% identical to

TC 2.A.22.2.8 / Q6VS78 Cation-dependent nutrient amino acid transporter, AAT1 (L-phe > cys > his > ala > ser > met > ile > tyr > D-phe > thr > gly) from Aedes aegypti (Yellowfever mosquito)
PFams: SNF
677 amino acids: PaperBLAST, CDD, TCDB::Q6VS78
41% identical to

TC 2.A.22.2.11 / Q99884 Sodium-dependent proline transporter (Solute carrier family 6 member 7) from Homo sapiens
PFams: SNF
636 amino acids: PaperBLAST, CDD

NTDO_CAEEL / Q03614 Sodium-dependent dopamine transporter; DA transporter; DAT from Caenorhabditis elegans
TC 2.A.22.1.4 / Q03614 Antidepressant- and cocaine-sensitive dopamine transporter, T23G5.5 (Km for dopamine, 1.2 µM; dependent on extracellular Na+ and Cl-; blocked by cocaine and D-amphetamine) (Jayanthi et al. 1998) from Caenorhabditis elegans
PFams: SNF
615 amino acids: PaperBLAST, CDD, SwissProt::Q03614
41% identical to

TC 2.A.22.2.11 / Q99884 Sodium-dependent proline transporter (Solute carrier family 6 member 7) from Homo sapiens
PFams: SNF
636 amino acids: PaperBLAST, CDD