Other Characterized Proteins Similar to proW

GapMind for catabolism of small carbon sources

Other Characterized Proteins Similar to proW

Finding the characterized proteins for proW (proline ABC transporter, permease component ProW) in L-proline catabolism

Or see clustering for step proW

Or see all steps for L-proline catabolism

Or cluster curated proteins matching a keyword

Definition of proW

Curated sequence P14176: Glycine betaine/proline betaine transport system permease protein ProW. ProW aka B2678, component of Glycine betaine/proline porter, ProU or ProVWX (also transports proline betaine, carnitine, dimethyl proline, homobetaine, γ-butyrobetaine and choline with low affinity). glycine betaine ABC transporter membrane subunit ProW (EC 7.6.2.9). glycine betaine ABC transporter membrane subunit ProW (EC 7.6.2.9)
Ignore hits to E0SCY2 when looking for 'other' hits (Glycine betaine/choline transport system permease protein OusW)

Fetched 1 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 14 other characterized sequences. (Found 15 hits including self hits.)

Removing ignored items reduces this to 13 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for proW.)

OPUAB_BACSU / P46921 Glycine betaine transport system permease protein OpuAB from Bacillus subtilis (strain 168)
TC 3.A.1.12.2 / P46921 OPAB aka OpuAB, component of Glycine betaine OpuAA/AB/AC porter (also transports dimethylsulfonioacetate and dimethylsulfoniopropionate) from Bacillus subtilis
PFams: BPD_transp_1
Heteromeric, 282 amino acids: PaperBLAST, CDD, SwissProt::P46921
47% identical to

b2678 glycine betaine ABC transporter membrane subunit ProW (EC 7.6.2.9) from Escherichia coli K-12 substr. MG1655
P14176 glycine betaine ABC transporter membrane subunit ProW (EC 7.6.2.9) from Escherichia coli (strain K12)
PROW_ECOLI / P14176 Glycine betaine/proline betaine transport system permease protein ProW from Escherichia coli (strain K12)
TC 3.A.1.12.1 / P14176 ProW aka B2678, component of Glycine betaine/proline porter, ProU or ProVWX (also transports proline betaine, carnitine, dimethyl proline, homobetaine, γ-butyrobetaine and choline with low affinity) from Escherichia coli
PFams: BPD_transp_1
Heteromeric, 354 amino acids: PaperBLAST, CDD

TC 3.A.1.12.5 / Q9RQ05 BusAB aka OPUABC, component of Uptake system for glycine-betaine (high affinity) and proline (low affinity) (OpuAA-OpuABC) or BusAA-ABC of Lactococcus lactis). BusAA, the ATPase subunit, has a C-terminal tandem cystathionine β-synthase (CBS) domain which is the cytoplasmic K+ sensor for osmotic stress (osmotic strength)while the BusABC subunit has the membrane and receptor domains fused to each other (Biemans-Oldehinkel et al., 2006; Mahmood et al., 2006; Gul et al. 2012). An N-terminal amphipathic α-helix of OpuA is necessary for high activity but is not critical for biogenesis or the ionic regulation of transport from Lactococcus lactis
PFams: BPD_transp_1, OpuAC
Heteromeric, 573 amino acids: PaperBLAST, CDD, TCDB::Q9RQ05
47% identical to

Q7DAU8 ABC-type quaternary amine transporter (EC 7.6.2.9) from Lactococcus lactis
PFams: BPD_transp_1, OpuAC
573 amino acids: PaperBLAST, CDD, BRENDA::Q7DAU8
46% identical to

GBUB_LISM4 / Q9RR45 Glycine betaine/carnitine transport permease protein GbuB from Listeria monocytogenes serotype 1/2a (strain 10403S)
PFams: BPD_transp_1
282 amino acids: PaperBLAST, CDD, SwissProt::Q9RR45
47% identical to

AO356_09615 ABC transporter for L-Histidine, permease component from Pseudomonas fluorescens FW300-N2C3
PFams: BPD_transp_1
Heteromeric, 283 amino acids: PaperBLAST, CDD, reanno::pseudo5_N2C3_1:AO356_09615
47% identical to

TC 3.A.1.12.6 / Q9KKE2 HutW aka HISW, component of Uptake system for hisitidine, proline, proline-betaine and glycine-betaine from Rhizobium meliloti (Sinorhizobium meliloti)
PFams: BPD_transp_1
Heteromeric, 285 amino acids: PaperBLAST, CDD, TCDB::Q9KKE2
47% identical to

TC 3.A.1.12.7 / Q92N36 ChoW, component of High affinity (3 μM) choline-specific uptake system from Rhizobium meliloti (Sinorhizobium meliloti)
PFams: BPD_transp_1
Heteromeric, 281 amino acids: PaperBLAST, CDD, TCDB::Q92N36
44% identical to

TC 3.A.1.12.9 / Q8U4S4 OtaB, component of The salt-induced glycine betaine OtaABC transporter from Methanosarcina mazei
PFams: BPD_transp_1
Heteromeric, 277 amino acids: PaperBLAST, CDD, TCDB::Q8U4S4
44% identical to

TC 3.A.1.12.13 / Q7CXG1 ABC transporter, membrane spanning protein (Proline/glycine betaine), component of High affinity (2mμM) choline uptake porter. The choline binding receptor exhibits a venus fly trap mechanism of substrate binding. (ChoX binds acetyl choline and betaine with low affinity (80μM and 470μM, respectively) (Aktas et al., 2011) (most similar to 3.A.1.12.7) from Agrobacterium tumefaciens (strain C58 / ATCC 33970)
PFams: BPD_transp_1
Heteromeric, 343 amino acids: PaperBLAST, CDD, TCDB::Q7CXG1
43% identical to

TC 3.A.1.12.12 / Q9HTI7 Probable permease of ABC transporter, component of The CbcWV/CbcX (choline)/CaiX (carnitine)/BetX (betaine) transporter with 3 binding receptors for distinct quaternary ammonium compounds. Only the ligand-bound receptor binds to the transporter with high affinity from Pseudomonas aeruginosa
PFams: BPD_transp_1
Heteromeric, 279 amino acids: PaperBLAST, CDD, TCDB::Q9HTI7
41% identical to

AO356_13810 ABC transporter for Carnitine, permease component from Pseudomonas fluorescens FW300-N2C3
PFams: BPD_transp_1
Heteromeric, 281 amino acids: PaperBLAST, CDD, reanno::pseudo5_N2C3_1:AO356_13810
40% identical to

AO353_07785 ABC transporter for Carnitine, permease component from Pseudomonas fluorescens FW300-N2E3
PFams: BPD_transp_1
Heteromeric, 281 amino acids: PaperBLAST, CDD, reanno::pseudo3_N2E3:AO353_07785
40% identical to

Pf6N2E2_4682 ABC transporter for Carnitine, permease component from Pseudomonas fluorescens FW300-N2E2
PFams: BPD_transp_1
Heteromeric, 281 amino acids: PaperBLAST, CDD, reanno::pseudo6_N2E2:Pf6N2E2_4682
40% identical to

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for proW.)

OUSW_DICD3 / E0SCY2 Glycine betaine/choline transport system permease protein OusW from Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))
PFams: BPD_transp_1
406 amino acids: PaperBLAST, CDD, SwissProt::E0SCY2
79% identical to