Other Characterized Proteins Similar to acn

GapMind for catabolism of small carbon sources

Other Characterized Proteins Similar to acn

Finding the characterized proteins for acn ((2R,3S)-2-methylcitrate dehydratase) in propionate catabolism

Or see clustering for step acn

Or see all steps for propionate catabolism

Or cluster curated proteins matching a keyword

Definition of acn

Curated proteins or TIGRFams with EC 4.2.1.99
Ignore hits to items matching 4.2.1.3 when looking for 'other' hits
Comment: (2R,3S)-2-methylcitrate dehydratases are closely related to aconitate hydratases (EC 4.2.1.3), which are ignored.

Fetched 10 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 24 other characterized sequences. (Found 34 hits including self hits.)

Removing ignored items reduces this to 4 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for acn.)

A0A0M3N196 phosphinomethylmalate isomerase (EC 4.2.1.166) from Kitasatospora phosalacinea
PFams: Aconitase, Aconitase_C
882 amino acids: PaperBLAST, CDD, metacyc::MONOMER-19770
55% identical to

ACNA_THET8 / Q5SMF6 Aconitate hydratase A; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; Iron-responsive protein-like; IRP-like; Probable 2-methyl-cis-aconitate hydratase; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
PFams: Aconitase, Aconitase_C
902 amino acids: PaperBLAST, CDD

Q4JFF1 phosphinomethylmalate isomerase (EC 4.2.1.166) from Streptomyces viridochromogenes
PFams: Aconitase, Aconitase_C
889 amino acids: PaperBLAST, CDD, BRENDA::Q4JFF1
52% identical to

ACNA_SALTY / Q8ZP52 Aconitate hydratase A; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; 2-methyl-cis-aconitate hydratase; Iron-responsive protein-like; IRP-like; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Q8ZP52 aconitate hydratase 1 (EC 4.2.1.99) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
PFams: Aconitase, Aconitase_C
891 amino acids: PaperBLAST, CDD

IREB2_MOUSE / Q811J3 Iron-responsive element-binding protein 2; IRE-BP 2; Iron regulatory protein 2; IRP2 from Mus musculus (Mouse)
PFams: Aconitase, Aconitase, Aconitase_C
963 amino acids: PaperBLAST, CDD, SwissProt::Q811J3
52% identical to

IREB2_HUMAN / P48200 Iron-responsive element-binding protein 2; IRE-BP 2; Iron regulatory protein 2; IRP2 from Homo sapiens (Human)
PFams: Aconitase, Aconitase, Aconitase_C
963 amino acids: PaperBLAST, CDD, SwissProt::P48200
51% identical to

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for acn.)

b1276 aconitate hydratase 1 from Escherichia coli K-12 substr. MG1655
ACNA_ECOLI / P25516 Aconitate hydratase A; ACN; Aconitase; Iron-responsive protein-like; IRP-like; RNA-binding protein; Stationary phase enzyme; EC 4.2.1.3 from Escherichia coli (strain K12)
P25516 aconitate hydratase (EC 4.2.1.3) from Escherichia coli
P25516 aconitate hydratase 1 from Escherichia coli (strain K12)
CH_002745 aconitate hydratase 1; EC 4.2.1.3 from Escherichia coli K12
PFams: Aconitase, Aconitase_C
891 amino acids: PaperBLAST, CDD, BRENDA::P25516
92% identical to

ACND_SHEON / Q8EJW3 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming); Aconitate hydratase; ACN; Aconitase; EC 4.2.1.117; EC 4.2.1.3 from Shewanella oneidensis (strain MR-1)
Q8EJW3 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming) (EC 4.2.1.117) from Shewanella oneidensis
PFams: Aconitase, Aconitase_C
867 amino acids: PaperBLAST, CDD, BRENDA::Q8EJW3
83% identical to

ACNA_CUPNE / Q937N8 Aconitate hydratase A; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; Iron-responsive protein-like; IRP-like; Probable 2-methyl-cis-aconitate hydratase; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Cupriavidus necator (Alcaligenes eutrophus) (Ralstonia eutropha)
PFams: Aconitase, Aconitase_C
869 amino acids: PaperBLAST, CDD

Q9RIL1 aconitate hydratase (EC 4.2.1.3) from Streptomyces viridochromogenes
PFams: Aconitase, Aconitase_C
931 amino acids: PaperBLAST, CDD, BRENDA::Q9RIL1
70% identical to

ACNA_MYCTU / O53166 Aconitate hydratase A; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; Iron-responsive protein-like; IRP-like; Probable 2-methyl-cis-aconitate hydratase; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
O53166 aconitase from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PFams: Aconitase, Aconitase_C
943 amino acids: PaperBLAST, CDD

HP15_3433 Aconitate hydratase (EC 4.2.1.3) from Marinobacter adhaerens HP15
PFams: Aconitase, Aconitase_C
919 amino acids: PaperBLAST, CDD, reanno::Marino:GFF3491
65% identical to

ACON_LEGPH / P37032 Aconitate hydratase A; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; IP210; Iron-responsive protein-like; IRP-like; Major iron-containing protein; MICP; Probable 2-methyl-cis-aconitate hydratase; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
PFams: Aconitase, Aconitase_C
891 amino acids: PaperBLAST, CDD

P56418 aconitase (EC 4.2.1.3) from Helicobacter pylori (strain ATCC 700392 / 26695)
PFams: Aconitase_B_N, Aconitase_2_N, Aconitase
852 amino acids: PaperBLAST, CDD, metacyc::HP0779-MONOMER
61% identical to

b0118 AcnB (EC 4.2.1.99) from Escherichia coli K-12 substr. MG1655
ACNB_ECOLI / P36683 Aconitate hydratase B; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; 2-methyl-cis-aconitate hydratase; Iron-responsive protein-like; IRP-like; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Escherichia coli (strain K12)
P36683 aconitate hydratase (EC 4.2.1.3) from Escherichia coli
P36683 AcnB (EC 4.2.1.99) from Escherichia coli (strain K12)
GB|AAZ86920.1 aconitate hydratas; EC 4.2.1.3 from Escherichia coli
PFams: Aconitase_B_N, Aconitase_2_N, Aconitase
865 amino acids: PaperBLAST, CDD

A0A2X5AHR8 aconitate hydratase (EC 4.2.1.3) from Helicobacter pylori
PFams: Aconitase_B_N, Aconitase_2_N, Aconitase
852 amino acids: PaperBLAST, CDD, BRENDA::A0A2X5AHR8
60% identical to

ACNA_BACSU / P09339 Aconitate/2-methylaconitate hydratase; Aconitate hydratase A; ACN; Aconitase; Iron-responsive protein-like; IRP-like; RNA-binding protein; EC 4.2.1.-; EC 4.2.1.3 from Bacillus subtilis (strain 168)
P09339 aconitate hydratase (EC 4.2.1.3) from Bacillus subtilis
PFams: Aconitase, Aconitase_C
909 amino acids: PaperBLAST, CDD, BRENDA::P09339
59% identical to

P28271 aconitate hydratase (EC 4.2.1.3) from Mus musculus
PFams: Aconitase, Aconitase_C
889 amino acids: PaperBLAST, CDD, BRENDA::P28271
56% identical to

Q63270 aconitate hydratase (EC 4.2.1.3) from Rattus norvegicus
PFams: Aconitase, Aconitase_C
889 amino acids: PaperBLAST, CDD, BRENDA::Q63270
56% identical to

D3GQL1 aconitate hydratase (EC 4.2.1.3) from Citrus clementina
PFams: Aconitase, Aconitase_C
898 amino acids: PaperBLAST, CDD, BRENDA::D3GQL1
56% identical to

D3GQL2 aconitate hydratase (EC 4.2.1.3) from Citrus clementina
PFams: Aconitase, Aconitase_C
898 amino acids: PaperBLAST, CDD, BRENDA::D3GQL2
56% identical to

D3GQL0 aconitate hydratase (EC 4.2.1.3) from Citrus clementina
PFams: Aconitase, Aconitase_C
900 amino acids: PaperBLAST, CDD, BRENDA::D3GQL0
55% identical to

ACOC_HUMAN / P21399 Cytoplasmic aconitate hydratase; Aconitase; Citrate hydro-lyase; Ferritin repressor protein; Iron regulatory protein 1; IRP1; Iron-responsive element-binding protein 1; IRE-BP 1; EC 4.2.1.3 from Homo sapiens (Human)
P21399 aconitate hydratase (EC 4.2.1.3) from Homo sapiens
P21399 cytoplasmic aconitate hydratase from Homo sapiens
PFams: Aconitase, Aconitase_C
889 amino acids: PaperBLAST, CDD, BRENDA::P21399
56% identical to

ACO3M_ARATH / Q9SIB9 Aconitate hydratase 3, mitochondrial; Aconitase 3; mACO1; Citrate hydro-lyase 3; EC 4.2.1.3 from Arabidopsis thaliana (Mouse-ear cress)
Q9SIB9 aconitate hydratase (EC 4.2.1.3) from Arabidopsis thaliana
PFams: Aconitase, Aconitase_C
990 amino acids: PaperBLAST, CDD, BRENDA::Q9SIB9
56% identical to

ACO1_ARATH / Q42560 Aconitate hydratase 1; Aconitase 1; Citrate hydro-lyase 1; EC 4.2.1.3 from Arabidopsis thaliana (Mouse-ear cress)
Q42560 aminocyclopropanecarboxylate oxidase (EC 1.14.17.4) from Arabidopsis thaliana
Q42560 aconitase from Arabidopsis thaliana
PFams: Aconitase, Aconitase_C
898 amino acids: PaperBLAST, CDD, BRENDA::Q42560
55% identical to

A0A090AMG4 aconitate hydratase (EC 4.2.1.3) from Achromobacter denitrificans
PFams: Aconitase, Aconitase_C
901 amino acids: PaperBLAST, CDD, BRENDA::A0A090AMG4
55% identical to

ACO2M_ARATH / Q94A28 Aconitate hydratase 2, mitochondrial; Aconitase 2; mACO2; Citrate hydro-lyase 2; EC 4.2.1.3 from Arabidopsis thaliana (Mouse-ear cress)
PFams: Aconitase, Aconitase_C
995 amino acids: PaperBLAST, CDD, SwissProt::Q94A28
55% identical to

Q9NFX3 aconitate hydratase (EC 4.2.1.3) from Drosophila melanogaster
PFams: Aconitase, Aconitase_C
902 amino acids: PaperBLAST, CDD, BRENDA::Q9NFX3
55% identical to

Q9NFX2 aconitate hydratase (EC 4.2.1.3) from Drosophila melanogaster
PFams: Aconitase, Aconitase_C
899 amino acids: PaperBLAST, CDD, BRENDA::Q9NFX2
55% identical to

ACOC_CAEEL / Q23500 Probable cytoplasmic aconitate hydratase; Aconitase; Citrate hydro-lyase; Gex-3-interacting protein 22; EC 4.2.1.3 from Caenorhabditis elegans
Q23500 aconitate hydratase (EC 4.2.1.3) from Caenorhabditis elegans
PFams: Aconitase, Aconitase_C
887 amino acids: PaperBLAST, CDD, BRENDA::Q23500
54% identical to