GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for prpC (2-methylcitrate synthase) in propionate catabolism

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Definition of prpC

Fetched 19 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 19 of these sequences

Found 2 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 372-398 amino acids (not heteromeric)

b0333 2-methylcitrate synthase (EC 2.3.3.5; EC 2.3.3.16; EC 2.3.3.1) from Escherichia coli K-12 substr. MG1655
PRPC_ECOLI / P31660 2-methylcitrate synthase; 2-MCS; MCS; (2S,3S)-2-methylcitrate synthase; Citrate synthase; EC 2.3.3.5; EC 2.3.3.16 from Escherichia coli (strain K12)
P31660 2-methylcitrate synthase (EC 2.3.3.5) from Escherichia coli
P31660 2-methylcitrate synthase (EC 2.3.3.5; EC 2.3.3.16) from Escherichia coli (strain K12)
GB|AP_000985.1 2-methylcitrate synthase; EC 2.3.3.5 from Escherichia coli K12
PFams: Citrate_synt
389 amino acids: PaperBLAST, CDD, Compare to cluster

MMGD_BACSU / P45858 Citrate/2-methylcitrate synthase; 2-methylcitrate synthase; 2-MCS; MCS; Citrate synthase; EC 2.3.3.-; EC 2.3.3.16 from Bacillus subtilis (strain 168)
P45858 citrate synthase (unknown stereospecificity) (EC 2.3.3.16) from Bacillus subtilis
PFams: Citrate_synt
372 amino acids: PaperBLAST, CDD, Compare to cluster

Q2Z1A8 2-methylcitrate synthase (EC 2.3.3.5) from Cupriavidus necator
PFams: Citrate_synt
398 amino acids: PaperBLAST, CDD, Compare to cluster

PRPC_SALTY / Q56063 2-methylcitrate synthase; 2-MCS; mcs; Citrate synthase; EC 2.3.3.5; EC 2.3.3.16 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Q56063 2-methylcitrate synthase (EC 2.3.3.5) from Salmonella enterica subsp. enterica serovar Typhimurium
Q56063 2-methylcitrate synthase (EC 2.3.3.5) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
PFams: Citrate_synt
389 amino acids: PaperBLAST, CDD, Compare to cluster

PRPC1_CORGL / Q8NSH7 2-methylcitrate synthase 1; 2-MCS; MCS; Citrate synthase 1; CS; EC 2.3.3.5; EC 2.3.3.16 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
Q8NSH7 2-methylcitrate synthase (EC 2.3.3.5) from Corynebacterium glutamicum
PFams: Citrate_synt
381 amino acids: PaperBLAST, CDD, Compare to cluster

PRPC2_CORGL / Q8NSL1 2-methylcitrate synthase 2; 2-MCS; MCS; Citrate synthase 2; CS; EC 2.3.3.5; EC 2.3.3.16 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
Q8NSL1 2-methylcitrate synthase (EC 2.3.3.5) from Corynebacterium glutamicum
PFams: Citrate_synt
383 amino acids: PaperBLAST, CDD, Compare to cluster

Q8X694 2-methylcitrate synthase (EC 2.3.3.5) from Escherichia coli
PFams: Citrate_synt
389 amino acids: PaperBLAST, CDD, Compare to cluster

Q9I5E3 2-methylcitrate synthase (EC 2.3.3.5) from Pseudomonas aeruginosa
PFams: Citrate_synt
375 amino acids: PaperBLAST, CDD, Compare to cluster

Q9KSC1 2-methylcitrate synthase (EC 2.3.3.5) from Vibrio cholerae
PFams: Citrate_synt
377 amino acids: PaperBLAST, CDD, Compare to cluster

PRPC_MYCTE / H8F0D7 2-methylcitrate synthase; 2-MCS; MCS; Citrate synthase; CS; EC 2.3.3.5; EC 2.3.3.16 from Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)
PRPC_MYCTU / I6Y9Q3 2-methylcitrate synthase; 2-MCS; MCS; Citrate synthase; EC 2.3.3.5; EC 2.3.3.16 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PFams: Citrate_synt
393 amino acids: PaperBLAST, CDD, Compare to cluster

PRPC_ABDS2 / O34002 2-methylcitrate synthase; 2-MCS; MCS; Citrate synthase; EC 2.3.3.5; EC 2.3.3.16 from Antarctic bacterium DS2-3R
O34002 citrate (Si)-synthase (EC 2.3.3.1) from antarctic bacterium DS2-3R
PFams: Citrate_synt
379 amino acids: PaperBLAST, CDD, Compare to cluster

PRPC_SHEON / Q8EJW2 2-methylcitrate synthase; 2-MCS; MCS; Citrate synthase; EC 2.3.3.5; EC 2.3.3.16 from Shewanella oneidensis (strain MR-1)
SO0344 2-methylcitrate synthase (EC 2.3.3.5) from Shewanella oneidensis MR-1
PFams: Citrate_synt
375 amino acids: PaperBLAST, CDD, Compare to cluster

PRPC_CUPNE / Q937N9 2-methylcitrate synthase; 2-MCS; MCS; Citrate synthase; EC 2.3.3.5; EC 2.3.3.16 from Cupriavidus necator (Alcaligenes eutrophus) (Ralstonia eutropha)
Q937N9 2-methylcitrate synthase (EC 2.3.3.5) from Cupriavidus metallidurans
PFams: Citrate_synt
385 amino acids: PaperBLAST, CDD, Compare to cluster

Pf6N2E2_6062 2-methylcitrate synthase (EC 2.3.3.5) from Pseudomonas fluorescens FW300-N2E2
PFams: Citrate_synt
375 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 460-472 amino acids (not heteromeric)

PRPC_ASPFC / B0YD89 2-methylcitrate synthase, mitochondrial; Methylcitrate synthase; (2S,3S)-2-methylcitrate synthase; Citrate synthase 2; EC 2.3.3.5; EC 2.3.3.16 from Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus)
PRPC_ASPFM / Q50I20 2-methylcitrate synthase, mitochondrial; Methylcitrate synthase; (2S,3S)-2-methylcitrate synthase; Citrate synthase 1; EC 2.3.3.5; EC 2.3.3.16 from Neosartorya fumigata (Aspergillus fumigatus)
Q50I20 2-methylcitrate synthase (EC 2.3.3.5) from Aspergillus fumigatus
GI|63028051 methylcitrate synthase; EC 2.3.3.5 from Aspergillus fumigatus
PFams: Citrate_synt
465 amino acids: PaperBLAST, CDD, Compare to cluster

PRPC_NECHA / C7C435 2-methylcitrate synthase, mitochondrial; Methylcitrate synthase; (2S,3S)-2-methylcitrate synthase; Citrate synthase 2; EC 2.3.3.5; EC 2.3.3.16 from Nectria haematococca
PFams: Citrate_synt
472 amino acids: PaperBLAST, CDD, Compare to cluster

PRPC_GIBMO / C7C436 2-methylcitrate synthase, mitochondrial; Methylcitrate synthase; (2S,3S)-2-methylcitrate synthase; Citrate synthase 2; EC 2.3.3.5; EC 2.3.3.16 from Gibberella moniliformis (Maize ear and stalk rot fungus) (Fusarium verticillioides)
PFams: Citrate_synt
472 amino acids: PaperBLAST, CDD, Compare to cluster

PRPC_YARLI / Q6C793 2-methylcitrate synthase, mitochondrial; Methylcitrate synthase; (2S,3S)-2-methylcitrate synthase; Citrate synthase 2; EC 2.3.3.5; EC 2.3.3.16 from Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
PFams: Citrate_synt
465 amino acids: PaperBLAST, CDD, Compare to cluster

PRPC_EMENI / Q9TEM3 2-methylcitrate synthase, mitochondrial; Methylcitrate synthase; (2S,3S)-2-methylcitrate synthase; Citrate synthase 2; EC 2.3.3.5; EC 2.3.3.16 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Q9TEM3 citrate synthase (unknown stereospecificity) (EC 2.3.3.16) from Aspergillus nidulans
GI|5763968 methylcitrate synthase; EC 2.3.3.5 from Emericella nidulans
PFams: Citrate_synt
460 amino acids: PaperBLAST, CDD, Compare to cluster