Other Characterized Proteins Similar to yjcH

Finding the characterized proteins for yjcH (putative small subunit of pyruvate transporter (yjcH-like)) in pyruvate catabolism

Or see clustering for step yjcH

Or see all steps for pyruvate catabolism

Or cluster curated proteins matching a keyword

Definition of yjcH

• Curated sequence GFF1742: required for pyruvate transport, with PS417_08865 (actP-like)
• Curated sequence AZOBR_RS02935: required for pyruvate transport, with AZOBR_RS02940
• Curated sequence Pf1N1B4_3672: required for pyruvate transport, with Pf1N1B4_3673 (actP-like)
• Curated sequence Pf6N2E2_5848: required for pyruvate transport, with Pf6N2E2_5849 (actP-like)
• Ignore hits to 18096 when looking for 'other' hits (DUF485 domain-containing inner membrane protein YjcH. required for glycolate transport, with actP)
• UniProt sequence E4PHQ1: SubName: Full=Membrane protein containing probable solute: sodium symporter, small subunit domain {ECO:0000313|EMBL:ADP97016.1};
• Curated sequence GFF345: small component of D-alanine uptake system, with Psest_0347 (actP-like)
• Comment: This is the yjcH-like small subunit. These are similar to E. coli b4068/yjcH/18096, involved in glycolate & acetate transport, so ignore that. Added Marinobacter HP15_1252 (E4PHQ1) because it has a specific phenotype (if mild) and fills the gap.

Fetched 6 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 3 other characterized sequences. (Found 8 hits including self hits.)

Removing ignored items reduces this to 2 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for yjcH.)

Sama_1522 small component of lactate uptake system from Shewanella amazonensis SB2B
PFams: DUF4212
Heteromeric, 88 amino acids: PaperBLAST, CDD, reanno::SB2B:6937352
51% identical to

Psest_0346 small component of D-alanine uptake system, with Psest_0347 (actP-like) from Pseudomonas stutzeri RCH2
PFams: DUF4212
Heteromeric, 87 amino acids: PaperBLAST, CDD

Shew_2372 small component of L-lactate and L-malate uptake system from Shewanella loihica PV-4
PFams: DUF4212
Heteromeric, 88 amino acids: PaperBLAST, CDD, reanno::PV4:5209924
48% identical to

E4PHQ1 Membrane protein containing probable solute: sodium symporter, small subunit domain
88 amino acids: PaperBLAST, CDD

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for yjcH.)

b4068 required for glycolate transport, with actP from Escherichia coli BW25113
b4068 DUF485 domain-containing inner membrane protein YjcH from Escherichia coli K-12 substr. MG1655
PFams: DUF485
104 amino acids: PaperBLAST, CDD, ecocyc::YJCH-MONOMER
61% identical to

Pf1N1B4_3672 required for pyruvate transport, with Pf1N1B4_3673 (actP-like) from Pseudomonas fluorescens FW300-N1B4
PFams: DUF485
103 amino acids: PaperBLAST, CDD