Finding the characterized proteins for LmGT2 (D-ribose transporter LmGT2) in D-ribose catabolism
Or see clustering for step LmGT2
Or see all steps for D-ribose catabolism
Or cluster curated proteins matching a keyword
Definition of LmGT2
Fetched 1 sequences
Running ublast to find other characterized proteins with 40% identity and 70% coverage
Found hits to 5 other characterized sequences. (Found 6 hits including self hits.)
(Sequences that are similar to these will not be high-confidence candidates for LmGT2.)
TC 2.A.1.1.76 / O76486 Glucose transporter, GT1. GT1, 2, and 3 are homologues. GT2 and GT3 transport ribose as well as glucose at different rates. GT3 transports ribose with 6-fold lower efficiency due to two threonines in GT3 that are alanines in GT2. They are in two loops between TMSs 3, 4, and 7, 8 (Naula et al., 2010). GT1 is expressed in the flagellar membrane and may be both a glucose transporter and sensor, allowing the parasites to enter the stationary phase when they deplete glucose although in the absence of the sensor, they lose viability from Leishmania mexicana
PFams: Sugar_tr, MFS_1, Sugar_tr
610 amino acids: PaperBLAST, CDD, TCDB::O76486
95% identical to
TC 2.A.1.1.77 / O61059 The D-glucose/D-ribose transporter, LmGT2 (Most similar to 1.A.1.1.18) from Leishmania mexicana
PFams: Sugar_tr, MFS_1, Sugar_tr
567 amino acids: PaperBLAST, CDD
TC 2.A.1.1.78 / O61060 The glucose transporter, LmGT3 (homologous to LmGT2 (1.A.1.1.75)). Two threonine residues located in the hydrophilic loops connecting TMSs 3 & 4 and 7 & 8 of GT3 prevent transport of D-ribose. Changing these two residues to alanine (as in GT2) allows transport of ribose. Thus, loops 3-4 and 7-8 partially determine substrate specificity from Leishmania mexicana
PFams: Sugar_tr, MFS_1, Sugar_tr
566 amino acids: PaperBLAST, CDD, TCDB::O61060
92% identical to
TC 2.A.1.1.77 / O61059 The D-glucose/D-ribose transporter, LmGT2 (Most similar to 1.A.1.1.18) from Leishmania mexicana
PFams: Sugar_tr, MFS_1, Sugar_tr
567 amino acids: PaperBLAST, CDD
TC 2.A.1.1.18 / Q06222 Glucose/mannose/fructose transporter and high affinity sensor, Snf3p (regulates glucose transport via other systems) from Trypanosoma brucei brucei
PFams: Sugar_tr, MFS_1
529 amino acids: PaperBLAST, CDD, TCDB::Q06222
47% identical to
TC 2.A.1.1.77 / O61059 The D-glucose/D-ribose transporter, LmGT2 (Most similar to 1.A.1.1.18) from Leishmania mexicana
PFams: Sugar_tr, MFS_1, Sugar_tr
567 amino acids: PaperBLAST, CDD
TC 2.A.1.1.71 / B1PLM1 Hexose (glucose) transporter, GT4 (D2) (almost identical to 2.A.1.1.16) from Leishmania mexicana
PFams: Sugar_tr, MFS_1
627 amino acids: PaperBLAST, CDD, TCDB::B1PLM1
43% identical to
TC 2.A.1.1.77 / O61059 The D-glucose/D-ribose transporter, LmGT2 (Most similar to 1.A.1.1.18) from Leishmania mexicana
PFams: Sugar_tr, MFS_1, Sugar_tr
567 amino acids: PaperBLAST, CDD
TC 2.A.1.1.16 / Q01441 Low-affinity hexose (glucose, fructose, mannose, 2-deoxyglucose) uniporter from Leishmania donovani
PFams: Sugar_tr, MFS_1
558 amino acids: PaperBLAST, CDD, TCDB::Q01441
43% identical to
TC 2.A.1.1.77 / O61059 The D-glucose/D-ribose transporter, LmGT2 (Most similar to 1.A.1.1.18) from Leishmania mexicana
PFams: Sugar_tr, MFS_1, Sugar_tr
567 amino acids: PaperBLAST, CDD