GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for serP (L-serine permease SerP) in L-serine catabolism

Or see other characterized proteins similar to serP

Or see all steps for L-serine catabolism

Or cluster curated proteins matching a keyword

Definition of serP

Fetched 3 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 3 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 457-459 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

SERP1_LACLM / A2RI87 Serine permease SerP1 from Lactococcus lactis subsp. cremoris (strain MG1363)
PFams: AA_permease, AA_permease_2
459 amino acids: PaperBLAST, CDD, Compare to cluster

TC 2.A.3.1.20 / F2HQ24 Serine transporter, SerP2 or YdgB, of 459 aas and 12 TMSs (Trip et al. 2013). Transports L-alanine (Km = 20 μM), D-alanine (Km = 38 μM), L-serine, D-serine (Km = 356 μM) and glycine (Noens and Lolkema 2015). The encoding gene is adjacent to the one encoding SerP1 (TC# 2.A.3.1.21) from Lactococcus lactis subsp. lactis (strain CV56)
PFams: AA_permease, AA_permease_2
457 amino acids: PaperBLAST, CDD, Compare to cluster

TC 2.A.3.1.21 / F2HQ25 Serine uptake transporter, SerP1, of 259 aas and 12 TMSs (Trip et al. 2013). L-serine is the highest affinity substrate (Km = 18 μM), but SerP1 also transports L-threonine and L-cysteine (Km values = 20 - 40 μM) from Lactococcus lactis subsp. lactis (strain CV56)
PFams: AA_permease, AA_permease_2
459 amino acids: PaperBLAST, CDD, Compare to cluster