Other Characterized Proteins Similar to SOT

Finding the characterized proteins for SOT (sorbitol:H+ co-transporter SOT1 or SOT2) in D-sorbitol (glucitol) catabolism

Or see clustering for step SOT

Or see all steps for D-sorbitol (glucitol) catabolism

Or cluster curated proteins matching a keyword

Definition of SOT

• Curated sequence CH_091483: polyol transporter 5. Polyol transporter 5; Protein POLYOL TRANSPORTER 5; AtPLT5; Sugar-proton symporter PLT5. The broad specificity sugar/sugar alcohol (myo-inositol, glycerol, ribose, sorbitol, mannitol, xylitol, erythritol, etc) H+ symporter, AtPLT5 (transports a wide range of hexoses, pentoses, tetroses, sugar alcohols and a sugar acid, but not disaccharides) (Reinders et al., 2005) (expressed in roots, leaves and floral organs)
• Curated sequence AGG19156.1: Sorbitol (glucitol):H+ co-transporter, SOT2 (Km for sorbitol of 0.81 mM) of 491 aas and 12 TMSs (Gao et al. 2003). SOT2 of Prunus cerasus is mainly expressed only early in fruit development and not in leaves
• Curated sequence AIU41385.1: Sorbitol (D-Glucitol):H+ co-transporter, SOT1 (Km for sorbitol of 0.64 mM) of 509 aas and 12 TMSs (Gao et al. 2003). SOT1 of P. cerasus is expressed throughout fruit development, but especially when growth and sorbitol accumulation rates are highest. In leaves, PcSOT1 expression is highest in young, expanding tissues, but substantially less in mature leaves
• Comment: Various monomeric transporters related to SOT1 or SOT2

Fetched 3 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 2 other characterized sequences. (Found 5 hits including self hits.)

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for SOT.)

TC 2.A.1.1.79 / Q1XF07 Polyol (xylitol):H+ symporter, PLT4 from Lotus japonicus
PFams: Sugar_tr, MFS_1
519 amino acids: PaperBLAST, CDD, TCDB::Q1XF07
76% identical to

PLT5_ARATH / Q8VZ80 Polyol transporter 5; Protein POLYOL TRANSPORTER 5; AtPLT5; Sugar-proton symporter PLT5 from Arabidopsis thaliana (Mouse-ear cress)
TC 2.A.1.1.34 / Q8VZ80 The broad specificity sugar/sugar alcohol (myo-inositol, glycerol, ribose, sorbitol, mannitol, xylitol, erythritol, etc) H+ symporter, AtPLT5 (transports a wide range of hexoses, pentoses, tetroses, sugar alcohols and a sugar acid, but not disaccharides) (Reinders et al., 2005) (expressed in roots, leaves and floral organs) from Arabidopsis thaliana (Mouse-ear cress)
RF|NP_188513.1 polyol transporter 5 from Arabidopsis thaliana
PFams: Sugar_tr, MFS_1
539 amino acids: PaperBLAST, CDD

TC 2.A.1.1.75 / Q9XIH7 The fructose/xylose:H+ symporter, PMT1 (polyol monosaccharide transporter-1). Also transports other substrates at lower rates. PMT2 is largely of the same sequence and function. Both are present in pollen and young xylem cells (Klepek et al., 2005). A similar ortholog has been identifed in pollen grains of Petunia hybrida from Arabidopsis thaliana
PFams: Sugar_tr, MFS_1
511 amino acids: PaperBLAST, CDD, TCDB::Q9XIH7
64% identical to

TC 2.A.1.1.122 / AGG19156.1 Sorbitol (glucitol):H+ co-transporter, SOT2 (Km for sorbitol of 0.81 mM) of 491 aas and 12 TMSs (Gao et al. 2003). SOT2 of Prunus cerasus is mainly expressed only early in fruit development and not in leaves from Pyrus pyrifolia
PFams: Sugar_tr, MFS_1
491 amino acids: PaperBLAST, CDD