GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for sdh (sorbitol dehydrogenase) in D-sorbitol (glucitol) catabolism

Or see other characterized proteins similar to sdh

Or see all steps for D-sorbitol (glucitol) catabolism

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Definition of sdh

Fetched 30 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 29 of these sequences

Found 4 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 345-371 amino acids (not heteromeric)

DHSO1_YEAST / P35497 Sorbitol dehydrogenase 1; SDH 1; Polyol dehydrogenase; Xylitol dehydrogenase; EC 1.1.1.-; EC 1.1.1.9 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
P35497 L-iditol 2-dehydrogenase (EC 1.1.1.14) from Saccharomyces cerevisiae
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
357 amino acids: PaperBLAST, CDD, Compare to cluster

Q07786 L-iditol 2-dehydrogenase (EC 1.1.1.14) from Saccharomyces cerevisiae
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
357 amino acids: PaperBLAST, CDD, Compare to cluster

Q3C2L6 L-iditol 2-dehydrogenase (EC 1.1.1.14) from Solanum lycopersicum
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
355 amino acids: PaperBLAST, CDD, Compare to cluster

Q5I6M3 L-iditol 2-dehydrogenase (EC 1.1.1.14) from Malus domestica
PFams: ADH_N, Glu_dehyd_C, ADH_zinc_N, ADH_zinc_N_2
368 amino acids: PaperBLAST, CDD, Compare to cluster

Q5I6M4 L-iditol 2-dehydrogenase (EC 1.1.1.14) from Malus domestica
PFams: ADH_N, Glu_dehyd_C, ADH_zinc_N, ADH_zinc_N_2
371 amino acids: PaperBLAST, CDD, Compare to cluster

Q06004 glucitol dehydrogenase monomer (EC 1.1.1.9; EC 1.1.1.14) from Bacillus subtilis (strain 168)
DHSO_BACSU / Q06004 Sorbitol dehydrogenase; SDH; Glucitol dehydrogenase; L-iditol 2-dehydrogenase; Polyol dehydrogenase; Xylitol dehydrogenase; EC 1.1.1.-; EC 1.1.1.14; EC 1.1.1.9 from Bacillus subtilis (strain 168)
GI|304153 L-iditol 2-dehydrogenase; EC 1.1.1.14 from Bacillus subtilis subsp. subtilis str. 168
PFams: ADH_N, ADH_zinc_N
353 amino acids: PaperBLAST, CDD, Compare to cluster

DHSO_SCHPO / P36624 Sorbitol dehydrogenase; SDH; Polyol dehydrogenase; Protein tms1; EC 1.1.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
RF|NP_595120.1 hexitol dehydrogenase (predicted); EC 1.1.1.- from Schizosaccharomyces pombe
PFams: ADH_N, ADH_zinc_N
360 amino acids: PaperBLAST, CDD, Compare to cluster

DHSO_SHEEP / P07846 Sorbitol dehydrogenase; SDH; L-iditol 2-dehydrogenase; Polyol dehydrogenase; Xylitol dehydrogenase; XDH; EC 1.1.1.-; EC 1.1.1.14; EC 1.1.1.9 from Ovis aries (Sheep)
PFams: ADH_N, Glu_dehyd_C, AlaDh_PNT_C, ADH_zinc_N
354 amino acids: PaperBLAST, CDD, Compare to cluster

DHSO_CHICK / P0DMQ6 Sorbitol dehydrogenase; SDH; Polyol dehydrogenase; EC 1.1.1.- from Gallus gallus (Chicken)
PFams: ADH_N, Glu_dehyd_C, ADH_zinc_N
355 amino acids: PaperBLAST, CDD, Compare to cluster

DHSO_RAT / P27867 Sorbitol dehydrogenase; SDH; L-iditol 2-dehydrogenase; Polyol dehydrogenase; Xylitol dehydrogenase; XDH; EC 1.1.1.-; EC 1.1.1.14; EC 1.1.1.9 from Rattus norvegicus (Rat)
PFams: ADH_N, Glu_dehyd_C, ADH_zinc_N
357 amino acids: PaperBLAST, CDD, Compare to cluster

DHSO_HUMAN / Q00796 Sorbitol dehydrogenase; SDH; (R,R)-butanediol dehydrogenase; L-iditol 2-dehydrogenase; Polyol dehydrogenase; Ribitol dehydrogenase; RDH; Xylitol dehydrogenase; XDH; EC 1.1.1.-; EC 1.1.1.4; EC 1.1.1.14; EC 1.1.1.56; EC 1.1.1.9 from Homo sapiens (Human)
PFams: ADH_N, Glu_dehyd_C, ADH_zinc_N
357 amino acids: PaperBLAST, CDD, Compare to cluster

DHSO_BOVIN / Q58D31 Sorbitol dehydrogenase; SDH; L-iditol 2-dehydrogenase; Polyol dehydrogenase; Xylitol dehydrogenase; XDH; EC 1.1.1.-; EC 1.1.1.14; EC 1.1.1.9 from Bos taurus (Bovine)
PFams: ADH_N, Glu_dehyd_C, AlaDh_PNT_C, ADH_zinc_N
356 amino acids: PaperBLAST, CDD, Compare to cluster

DHSO_MOUSE / Q64442 Sorbitol dehydrogenase; SDH; SORD; L-iditol 2-dehydrogenase; Polyol dehydrogenase; Xylitol dehydrogenase; XDH; EC 1.1.1.-; EC 1.1.1.14; EC 1.1.1.9 from Mus musculus (Mouse)
PFams: ADH_N, Glu_dehyd_C, AlaDh_PNT_C, ADH_zinc_N
357 amino acids: PaperBLAST, CDD, Compare to cluster

DHSO_ARATH / Q9FJ95 Sorbitol dehydrogenase; SDH; Polyol dehydrogenase; Ribitol dehydrogenase; RDH; Xylitol dehydrogenase; XDH; EC 1.1.1.-; EC 1.1.1.56; EC 1.1.1.9 from Arabidopsis thaliana (Mouse-ear cress)
PFams: ADH_N, Glu_dehyd_C, ADH_zinc_N, ADH_zinc_N_2
364 amino acids: PaperBLAST, CDD, Compare to cluster

Q876R2 D-sorbitol dehydrogenase (EC 1.1.1.14; EC 1.1.1.9) from Hypocrea jecorina
PFams: ADH_N, Glu_dehyd_C, ADH_zinc_N
363 amino acids: PaperBLAST, CDD, Compare to cluster

A2QM95 sorbitol dehydrogenase (EC 1.1.1.14) from Aspergillus niger (strain CBS 513.88 / FGSC A1513)
PFams: ADH_N, Glu_dehyd_C, ADH_zinc_N
369 amino acids: PaperBLAST, CDD, Compare to cluster

HSERO_RS17015 L-iditol 2-dehydrogenase (EC 1.1.1.14); D-xylulose reductase (EC 1.1.1.9) from Herbaspirillum seropedicae SmR1
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
345 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 244-260 amino acids (not heteromeric)

A9CES4 galactitol 2-dehydrogenase (EC 1.1.1.16) from Agrobacterium fabrum (strain C58 / ATCC 33970)
GDH_AGRFC / A9CES4 Galactitol 2-dehydrogenase; GDH; Sorbitol dehydrogenase; SorbD; EC 1.1.1.16; EC 1.1.1.- from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
PFams: adh_short, KR, adh_short_C2
256 amino acids: PaperBLAST, CDD, Compare to cluster

Q1J2J0 L-iditol 2-dehydrogenase (EC 1.1.1.14) from Deinococcus geothermalis
PFams: adh_short, Epimerase, KR, adh_short_C2
255 amino acids: PaperBLAST, CDD, Compare to cluster

SDH_RHOSH / Q59787 Sorbitol dehydrogenase; SDH; Galactitol 2-dehydrogenase; L-iditol 2-dehydrogenase; Polyol dehydrogenase; EC 1.1.1.-; EC 1.1.1.16; EC 1.1.1.14 from Rhodobacter sphaeroides (Rhodopseudomonas sphaeroides)
GI|2338763 L-iditol 2-dehydrogenase; EC 1.1.1.14 from Rhodobacter sphaeroides
PFams: adh_short, KR, adh_short_C2
256 amino acids: PaperBLAST, CDD, Compare to cluster

BPHYT_RS16120 sorbitol dehydrogenase, D-fructose forming (EC 1.1.1.14) from Burkholderia phytofirmans PsJN
PFams: adh_short, KR, adh_short_C2
260 amino acids: PaperBLAST, CDD, Compare to cluster

PGA1_c13170 Sorbitol dehydrogenase (EC 1.1.1.14) from Phaeobacter inhibens BS107
PFams: adh_short, Epimerase, KR, adh_short_C2
257 amino acids: PaperBLAST, CDD, Compare to cluster

PS417_11520 Sorbitol dehydrogenase (EC 1.1.1.14) from Pseudomonas simiae WCS417
PFams: adh_short, KR, adh_short_C2
257 amino acids: PaperBLAST, CDD, Compare to cluster

Ac3H11_2940 D-sorbitol 2-dehydrogenase (EC 1.1.1.14) from Acidovorax sp. GW101-3H11
PFams: adh_short, KR, adh_short_C2
244 amino acids: PaperBLAST, CDD, Compare to cluster

Pf6N2E2_1959 D-sorbitol dehydrogenase (EC 1.1.1.14) from Pseudomonas fluorescens FW300-N2E2
PFams: adh_short, KR, adh_short_C2
257 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 740-743 amino acids (heteromeric)

Q70JN9 gluconate 5-dehydrogenase (EC 1.1.1.69); D-sorbitol dehydrogenase (acceptor) (subunit 1/2) (EC 1.1.99.21) from Gluconobacter oxydans
PFams: PQQ_2, PQQ, PQQ_2
Heteromeric, 743 amino acids: PaperBLAST, CDD, Compare to cluster

Q8KIL1 D-sorbitol dehydrogenase large subunit (EC 1.1.99.21) from Gluconobacter thailandicus
PFams: PQQ_2, PQQ, PQQ_2, PQQ_3
Heteromeric, 740 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 4 126-126 amino acids (heteromeric)

Q70JP0 gluconate 5-dehydrogenase (EC 1.1.1.69); D-sorbitol dehydrogenase (acceptor) (subunit 2/2) (EC 1.1.99.21) from Gluconobacter oxydans
Heteromeric, 126 amino acids: PaperBLAST, CDD, Compare to cluster

Q8L1D5 D-sorbitol dehydrogenase small subunit (EC 1.1.99.21) from Gluconobacter thailandicus
Heteromeric, 126 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/1 heteromeric)

Q9KWR5 L-iditol 2-dehydrogenase (EC 1.1.1.14) from Gluconobacter oxydans
PFams: Mannitol_dh, Mannitol_dh_C
485 amino acids: PaperBLAST, CDD