Other Characterized Proteins Similar to sdc

Finding the characterized proteins for sdc (succinate:Na+ symporter Sdc) in succinate catabolism

Or see clustering for step sdc

Or see all steps for succinate catabolism

Or cluster curated proteins matching a keyword

Definition of sdc

• Curated sequence A4QAL6: The aerobic dicarboxylate (succinate (Km, 30 μM), fumarate (Km, 79
• Curated sequence Q21339: Sodium-dependent high-affinity dicarboxylate transporter 3; Na(+)/dicarboxylate cotransporter 3; NaDC-3; ceNaDC3. High affinity dicarboxylate:Na+ symporter, NaDC2 (INDY2) (relative affinities: fumarate > malate > α-ketoglutarate > maleate > succinate > lactate)
• Curated sequence Q2FFH9: The Na+ (or Li+):dicarboxylate (2:1) symporter, SdcS (catalyzes succinate:succinate antiport as well as electroneutral symport in reconstituted proteoliposomes
• Curated sequence Q65NC0: The Na+-coupled dicarboxylate (succinate; malate; fumarate) transporter, SdcL (transports aspartate, α-ketoglutarate and oxaloacetate with low affinity). Km for succinate, ~6
• Curated sequence Q9KNE0: Dicarboxylate (succinate, fumarate, malate) transporter, vcINDY
• Curated sequence Q99SX1: Sodium-dependent dicarboxylate transporter SdcS; Na(+)/dicarboxylate symporter
• Comment: (Sodium-dependent dicarboxylate transporter SdcS (Q99SX1) was not originally included because the description did not mention succinate specifically.)

Fetched 6 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 1 other characterized sequences. (Found 7 hits including self hits.)

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for sdc.)

NAD1_CAEEL / Q93655 Sodium-dependent low-affinity dicarboxylate transporter 1; Na(+)/dicarboxylate cotransporter 1; NaDC-1; ceNaDC1 from Caenorhabditis elegans
TC 2.A.47.1.7 / Q93655 Low affinity dicarboxylate:Na+ symporter, NaDC1 (INDY1) (relative affinities: succinate > fumarate > α-ketoglutarate > malate > lactate > maleate)
PFams: Na_sulph_symp, CitMHS, CitMHS
582 amino acids: PaperBLAST, CDD, SwissProt::Q93655
46% identical to

NAD3_CAEEL / Q21339 Sodium-dependent high-affinity dicarboxylate transporter 3; Na(+)/dicarboxylate cotransporter 3; NaDC-3; ceNaDC3 from Caenorhabditis elegans
TC 2.A.47.1.8 / Q21339 High affinity dicarboxylate:Na+ symporter, NaDC2 (INDY2) (relative affinities: fumarate > malate > α-ketoglutarate > maleate > succinate > lactate)
PFams: Na_sulph_symp, CitMHS
566 amino acids: PaperBLAST, CDD