Clusters of Characterized Proteins

Clustering the characterized proteins for cscB (sucrose:H+ symporter CscB) in sucrose catabolism

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Definition of cscB

• Curated sequence P30000: Sucrose permease; Sucrose transport protein. Sucrose:H+ symporter, CscB, also transports maltose (Peng et al. 2009). CscB recognizes not just sucrose but also fructose and lactulose, but glucopyranosides are not transported and do not inhibit sucrose transport
• UniProt sequence Q4KBP0: SubName: Full=Oligosaccharide:H+ symporter family protein {ECO:0000313|EMBL:AAY92507.1};
• Comment: PMID:29808622 report that PFL_3238 (Q4KBP0) is a sucrose permease; it is related to E. coli cscB

Fetched 2 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 2 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 415-429 amino acids (not heteromeric)

CSCB_ECOLX / P30000 Sucrose permease; Sucrose transport protein from Escherichia coli
TC 2.A.1.5.3 / P30000 Sucrose:H+ symporter, CscB, also transports maltose (Peng et al. 2009). CscB recognizes not just sucrose but also fructose and lactulose, but glucopyranosides are not transported and do not inhibit sucrose transport from Escherichia coli
PFams: LacY_symp, MFS_1, Nuc_H_symport, MFS_1_like
415 amino acids: PaperBLAST, CDD, Compare to cluster

Q4KBP0 Oligosaccharide:H+ symporter family protein
429 amino acids: PaperBLAST, CDD, Compare to cluster