Clusters of Characterized Proteins

Clustering the characterized proteins for thuE (sucrose ABC transporter, substrate-binding component ThuE) in sucrose catabolism

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Definition of thuE

• Curated sequence Q72H68: Trehalose/maltose-binding protein aka TT_C1627, component of The trehalose/maltose/sucrose/palatinose porter (TTC1627-9) plus MalK1 (ABC protein, shared with 3.A.1.1.24) (Silva et al. 2005; Chevance et al., 2006). The receptor (TTC1627) binds disaccharide alpha-glycosides, namely trehalose (alpha-1,1), sucrose (alpha-1,2), maltose (alpha-1,4), palatinose (alpha-1,6) and glucose
• Curated sequence Q9R9Q7: ThuE aka RB0311 aka SMB20325, component of Trehalose/maltose/sucrose porter (trehalose inducible). ABC transporter for D-Trehalose, periplasmic substrate-binding component
• UniProt sequence A0A166QFS3: SubName: Full=ABC transporter substrate-binding protein {ECO:0000313|EMBL:KZN20190.1};
• Comment: ThuEFGK in Sinorhizobium meliloti and TTC1627:TTC1629 + MalK1 in Thermus thermophilus. Also, a thuEFGK homolog in various Pseudomonas is important for fitness on sucrose, i.e., Pf1N1B4_5112:5116 or Psyr_0762:Psyr_0759, and is presumably a sucrose transporter. The N1B4 system is A0A166QFS3 A0A166QFV1 A0A161ZE72 A0A166QFW2.

Fetched 3 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 3 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 423-429 amino acids (2/3 heteromeric)

TC 3.A.1.1.25 / Q72H68 Trehalose/maltose-binding protein aka TT_C1627, component of The trehalose/maltose/sucrose/palatinose porter (TTC1627-9) plus MalK1 (ABC protein, shared with 3.A.1.1.24) (Silva et al. 2005; Chevance et al., 2006). The receptor (TTC1627) binds disaccharide alpha-glycosides, namely trehalose (alpha-1,1), sucrose (alpha-1,2), maltose (alpha-1,4), palatinose (alpha-1,6) and glucose from Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
PFams: SBP_bac_1, SBP_bac_8
Heteromeric, 429 amino acids: PaperBLAST, CDD, Compare to cluster

SM_b20325 ABC transporter for D-Trehalose, periplasmic substrate-binding component from Sinorhizobium meliloti 1021
TC 3.A.1.1.17 / Q9R9Q7 ThuE aka RB0311 aka SMB20325, component of Trehalose/maltose/sucrose porter (trehalose inducible) from Rhizobium meliloti (Sinorhizobium meliloti)
PFams: SBP_bac_1, SBP_bac_11, SBP_bac_8
Heteromeric, 423 amino acids: PaperBLAST, CDD, Compare to cluster

A0A166QFS3 ABC transporter substrate-binding protein
424 amino acids: PaperBLAST, CDD, Compare to cluster