GapMind for catabolism of small carbon sources

 

Other Characterized Proteins Similar to acs

Finding the characterized proteins for acs (acetyl-CoA synthetase, AMP-forming) in L-threonine catabolism

Or see clustering for step acs

Or see all steps for L-threonine catabolism

Or cluster curated proteins matching a keyword

Definition of acs

Fetched 31 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 21 other characterized sequences. (Found 52 hits including self hits.)

There are also 3 HMM-only high-coverage hits.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for acs.)

AAE5_ARATH / Q9FFE6 Probable acyl-activating enzyme 5, peroxisomal; AMP-binding protein 5; AtAMPBP5; EC 6.2.1.- from Arabidopsis thaliana (Mouse-ear cress)
PFams: AMP-binding, AMP-binding_C
552 amino acids: PaperBLAST, CDD, SwissProt::Q9FFE6
67% identical to

M4IQQ5 isobutanoate/2-methylbutanoate--CoA ligase (EC 6.2.1.1) from Humulus lupulus
PFams: AMP-binding, AMP-binding_C
556 amino acids: PaperBLAST, CDD

AAE6_ARATH / Q9FFE9 Probable acyl-activating enzyme 6; AMP-binding protein 6; AtAMPBP6; EC 6.2.1.- from Arabidopsis thaliana (Mouse-ear cress)
PFams: AMP-binding, AMP-binding_C
550 amino acids: PaperBLAST, CDD, SwissProt::Q9FFE9
67% identical to

M4IQQ5 isobutanoate/2-methylbutanoate--CoA ligase (EC 6.2.1.1) from Humulus lupulus
PFams: AMP-binding, AMP-binding_C
556 amino acids: PaperBLAST, CDD

AAE8_ARATH / Q9LQS1 Probable acyl-activating enzyme 8; AMP-binding protein 8; AtAMPBP8; EC 6.2.1.- from Arabidopsis thaliana (Mouse-ear cress)
PFams: AMP-binding, AMP-binding_C
544 amino acids: PaperBLAST, CDD, SwissProt::Q9LQS1
66% identical to

M4IQQ5 isobutanoate/2-methylbutanoate--CoA ligase (EC 6.2.1.1) from Humulus lupulus
PFams: AMP-binding, AMP-binding_C
556 amino acids: PaperBLAST, CDD

AAE2_ARATH / Q9SEY5 Probable acyl-activating enzyme 2; AMP-binding protein 2; AtAMPBP2; EC 6.2.1.- from Arabidopsis thaliana (Mouse-ear cress)
PFams: AMP-binding, AMP-binding_C
603 amino acids: PaperBLAST, CDD, SwissProt::Q9SEY5
65% identical to

M4IRL4 isovalerate--CoA ligase (EC 6.2.1.1) from Humulus lupulus
PFams: AMP-binding, AMP-binding_C
573 amino acids: PaperBLAST, CDD

AEE10_ARATH / Q9LPK7 Probable acyl-activating enzyme 10; AMP-binding protein 10; AtAMPBP10; EC 6.2.1.- from Arabidopsis thaliana (Mouse-ear cress)
PFams: AMP-binding, AMP-binding_C
549 amino acids: PaperBLAST, CDD, SwissProt::Q9LPK7
62% identical to

M4IQQ5 isobutanoate/2-methylbutanoate--CoA ligase (EC 6.2.1.1) from Humulus lupulus
PFams: AMP-binding, AMP-binding_C
556 amino acids: PaperBLAST, CDD

AEE9_ARATH / Q9LPK6 Probable acyl-activating enzyme 9; AMP-binding protein 9; AtAMPBP9; EC 6.2.1.- from Arabidopsis thaliana (Mouse-ear cress)
PFams: AMP-binding, AMP-binding_C
550 amino acids: PaperBLAST, CDD, SwissProt::Q9LPK6
62% identical to

M4IQQ5 isobutanoate/2-methylbutanoate--CoA ligase (EC 6.2.1.1) from Humulus lupulus
PFams: AMP-binding, AMP-binding_C
556 amino acids: PaperBLAST, CDD

AAE4_ARATH / O80658 Probable acyl-activating enzyme 4; AMP-binding protein 4; AtAMPBP4; EC 6.2.1.- from Arabidopsis thaliana (Mouse-ear cress)
PFams: AMP-binding, AMP-binding_C
545 amino acids: PaperBLAST, CDD, SwissProt::O80658
61% identical to

M4IQQ5 isobutanoate/2-methylbutanoate--CoA ligase (EC 6.2.1.1) from Humulus lupulus
PFams: AMP-binding, AMP-binding_C
556 amino acids: PaperBLAST, CDD

AAE1_ARATH / F4HUK6 Probable acyl-activating enzyme 1, peroxisomal; AMP-binding protein 1; AtAMPBP1; EC 6.2.1.- from Arabidopsis thaliana (Mouse-ear cress)
PFams: AMP-binding, AMP-binding_C
556 amino acids: PaperBLAST, CDD, SwissProt::F4HUK6
60% identical to

M4IRL4 isovalerate--CoA ligase (EC 6.2.1.1) from Humulus lupulus
PFams: AMP-binding, AMP-binding_C
573 amino acids: PaperBLAST, CDD

D0CV95 3-(methylthio)propionyl-CoA ligase (EC 6.2.1.44) from Ruegeria lacuscaerulensis
PFams: AMP-binding, AMP-binding_C
542 amino acids: PaperBLAST, CDD, BRENDA::D0CV95
56% identical to

AEE7_ARATH / Q8VZF1 Acetate/butyrate--CoA ligase AAE7, peroxisomal; AMP-binding protein 7; AtAMPBP7; Acetyl-CoA synthetase; Acyl-activating enzyme 7; Butyryl-CoA synthetase; Protein ACETATE NON-UTILIZING 1; EC 6.2.1.1; EC 6.2.1.2 from Arabidopsis thaliana (Mouse-ear cress)
PFams: AMP-binding, AMP-binding_C
569 amino acids: PaperBLAST, CDD

Q5LVM3 3-(methylthio)propionyl-CoA ligase (EC 6.2.1.44) from Ruegeria pomeroyi
PFams: AMP-binding, AMP-binding_C
542 amino acids: PaperBLAST, CDD, BRENDA::Q5LVM3
55% identical to

AEE7_ARATH / Q8VZF1 Acetate/butyrate--CoA ligase AAE7, peroxisomal; AMP-binding protein 7; AtAMPBP7; Acetyl-CoA synthetase; Acyl-activating enzyme 7; Butyryl-CoA synthetase; Protein ACETATE NON-UTILIZING 1; EC 6.2.1.1; EC 6.2.1.2 from Arabidopsis thaliana (Mouse-ear cress)
PFams: AMP-binding, AMP-binding_C
569 amino acids: PaperBLAST, CDD

Q9HWI3 3-(methylthio)propionyl-CoA ligase (EC 6.2.1.44) from Pseudomonas aeruginosa
PFams: AMP-binding, AMP-binding_C
540 amino acids: PaperBLAST, CDD, BRENDA::Q9HWI3
53% identical to

AEE7_ARATH / Q8VZF1 Acetate/butyrate--CoA ligase AAE7, peroxisomal; AMP-binding protein 7; AtAMPBP7; Acetyl-CoA synthetase; Acyl-activating enzyme 7; Butyryl-CoA synthetase; Protein ACETATE NON-UTILIZING 1; EC 6.2.1.1; EC 6.2.1.2 from Arabidopsis thaliana (Mouse-ear cress)
PFams: AMP-binding, AMP-binding_C
569 amino acids: PaperBLAST, CDD

J9ZU73 cinnamate:CoA ligase (EC 6.2.1.12) from Hypericum calycinum
PFams: AMP-binding, AMP-binding_C
572 amino acids: PaperBLAST, CDD, metacyc::MONOMER-17857
52% identical to

M4IQQ5 isobutanoate/2-methylbutanoate--CoA ligase (EC 6.2.1.1) from Humulus lupulus
PFams: AMP-binding, AMP-binding_C
556 amino acids: PaperBLAST, CDD

Q88J54 short chain acyl-CoA synthetase (EC 6.2.1.2) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
PFams: AMP-binding, AMP-binding_C
548 amino acids: PaperBLAST, CDD, metacyc::G1G01-2975-MONOMER
50% identical to

AEE7_ARATH / Q8VZF1 Acetate/butyrate--CoA ligase AAE7, peroxisomal; AMP-binding protein 7; AtAMPBP7; Acetyl-CoA synthetase; Acyl-activating enzyme 7; Butyryl-CoA synthetase; Protein ACETATE NON-UTILIZING 1; EC 6.2.1.1; EC 6.2.1.2 from Arabidopsis thaliana (Mouse-ear cress)
PFams: AMP-binding, AMP-binding_C
569 amino acids: PaperBLAST, CDD

Q4FP19 3-(methylthio)propionyl-CoA ligase (EC 6.2.1.44) from Candidatus Pelagibacter ubique
PFams: AMP-binding, AMP-binding_C
542 amino acids: PaperBLAST, CDD, BRENDA::Q4FP19
50% identical to

AEE7_ARATH / Q8VZF1 Acetate/butyrate--CoA ligase AAE7, peroxisomal; AMP-binding protein 7; AtAMPBP7; Acetyl-CoA synthetase; Acyl-activating enzyme 7; Butyryl-CoA synthetase; Protein ACETATE NON-UTILIZING 1; EC 6.2.1.1; EC 6.2.1.2 from Arabidopsis thaliana (Mouse-ear cress)
PFams: AMP-binding, AMP-binding_C
569 amino acids: PaperBLAST, CDD

AAE11_ARATH / Q9C8D4 Butyrate--CoA ligase AAE11, peroxisomal; Acyl-activating enzyme 11; Butyryl-CoA synthetase; EC 6.2.1.2 from Arabidopsis thaliana (Mouse-ear cress)
PFams: AMP-binding, AMP-binding_C
572 amino acids: PaperBLAST, CDD, SwissProt::Q9C8D4
48% identical to

M4IQQ5 isobutanoate/2-methylbutanoate--CoA ligase (EC 6.2.1.1) from Humulus lupulus
PFams: AMP-binding, AMP-binding_C
556 amino acids: PaperBLAST, CDD

PGA1_c11900 Propionate--CoA ligase (EC 6.2.1.17) from Phaeobacter inhibens BS107
PFams: ACAS_N, AMP-binding, AMP-binding_C
629 amino acids: PaperBLAST, CDD, reanno::Phaeo:GFF1175
51% identical to

ACSS3_RAT / A0A0G2K047 Acyl-CoA synthetase short-chain family member 3, mitochondrial; Acetate--CoA ligase 3; Acyl-CoA synthetase short-chain family member 3; Propionate--CoA ligase; EC 6.2.1.1; EC 6.2.1.17 from Rattus norvegicus (Rat)
A0A0G2K047 propionate-CoA ligase (EC 6.2.1.17) from Rattus norvegicus
PFams: ACAS_N, AMP-binding, AMP-binding_C
683 amino acids: PaperBLAST, CDD

I3PB36 cinnamate:CoA ligase (EC 6.2.1.12) from Petunia hybrida
PFams: AMP-binding, AMP-binding_C
570 amino acids: PaperBLAST, CDD, metacyc::MONOMER-17854
48% identical to

M4IQQ5 isobutanoate/2-methylbutanoate--CoA ligase (EC 6.2.1.1) from Humulus lupulus
PFams: AMP-binding, AMP-binding_C
556 amino acids: PaperBLAST, CDD

AAE12_ARATH / Q9SS00 Probable acyl-activating enzyme 12, peroxisomal; EC 6.2.1.- from Arabidopsis thaliana (Mouse-ear cress)
PFams: AMP-binding, AMP-binding_C
578 amino acids: PaperBLAST, CDD, SwissProt::Q9SS00
46% identical to

M4IQQ5 isobutanoate/2-methylbutanoate--CoA ligase (EC 6.2.1.1) from Humulus lupulus
PFams: AMP-binding, AMP-binding_C
556 amino acids: PaperBLAST, CDD

AAE20_ARATH / Q9SS01 Benzoate--CoA ligase, peroxisomal; Acyl-activating enzyme 20; Protein BENZOYLOXYGLUCOSINOLATE 1; EC 6.2.1.25 from Arabidopsis thaliana (Mouse-ear cress)
Q9SS01 benzoate-CoA ligase (EC 6.2.1.25) from Arabidopsis thaliana
PFams: AMP-binding, AMP-binding_C
580 amino acids: PaperBLAST, CDD, SwissProt::Q9SS01
46% identical to

M4IQQ5 isobutanoate/2-methylbutanoate--CoA ligase (EC 6.2.1.1) from Humulus lupulus
PFams: AMP-binding, AMP-binding_C
556 amino acids: PaperBLAST, CDD

B1YBY4 4-hydroxybutyrate-CoA ligase (EC 6.2.1.40) from Pyrobaculum neutrophilum
PFams: ACAS_N, AMP-binding, AMP-binding_C
629 amino acids: PaperBLAST, CDD, BRENDA::B1YBY4
47% identical to

Q2XNL6 acetate-CoA ligase (EC 6.2.1.1) from Methanothermobacter thermautotrophicus
PFams: ACAS_N, AMP-binding, AMP-binding_C
634 amino acids: PaperBLAST, CDD

b0335 propionyl-CoA synthetase (EC 6.2.1.17) from Escherichia coli K-12 substr. MG1655
P77495 propionate-CoA ligase (EC 6.2.1.17) from Escherichia coli
P77495 propionyl-CoA synthetase (EC 6.2.1.17) from Escherichia coli (strain K12)
PFams: ACAS_N, AMP-binding, AMP-binding_C
628 amino acids: PaperBLAST, CDD, BRENDA::P77495
40% identical to

ACSS3_HUMAN / Q9H6R3 Acyl-CoA synthetase short-chain family member 3, mitochondrial; Acetate--CoA ligase 3; Acyl-CoA synthetase short-chain family member 3; Propionate--CoA ligase; EC 6.2.1.1; EC 6.2.1.17 from Homo sapiens (Human)
PFams: ACAS_N, AMP-binding, AMP-binding_C
686 amino acids: PaperBLAST, CDD

HMM-only sequences

(Since these sequences' annotations are outside the definition for acs, HMM hits that are over 40% similar to these sequences will be scored as moderate confidence.)

A4YGF9 4-hydroxybutyrate-CoA ligase (EC 6.2.1.40) from Metallosphaera sedula
PFams: ACAS_N, AMP-binding, AMP-binding_C
664 amino acids: PaperBLAST, CDD

HPCAS_SULTO / Q973W5 3-hydroxypropionyl-coenzyme A synthetase; 3-hydroxypropionyl-CoA synthetase; EC 6.2.1.36 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii)
Q973W5 3-hydroxypropionyl-CoA synthase (EC 6.2.1.36) from Sulfurisphaera tokodaii
PFams: ACAS_N, AMP-binding, AMP-binding_C
659 amino acids: PaperBLAST, CDD

HPCAS_METS5 / A4YGR1 3-hydroxypropionyl-coenzyme A synthetase; 3-hydroxypropionyl-CoA synthetase; EC 6.2.1.36 from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)
A4YGR1 propionate-CoA ligase (EC 6.2.1.17); 3-hydroxypropionyl-CoA synthase (EC 6.2.1.36) from Metallosphaera sedula
A4YGR1 3-hydroxypropionyl-CoA synthetase subunit (EC 6.2.1.36) from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)
PFams: ACAS_N, AMP-binding, AMP-binding_C
661 amino acids: PaperBLAST, CDD