GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for iolA (malonate semialdehyde dehydrogenase (CoA-acylating)) in L-threonine catabolism

Or see other characterized proteins similar to iolA

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Or cluster curated proteins matching a keyword

Definition of iolA

Fetched 11 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 11 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 487-541 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

A0A081YAY7 malonate-semialdehyde dehydrogenase (EC 1.2.1.15); malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18); methylmalonate-semialdehyde dehydrogenase (CoA-acylating) (EC 1.2.1.27) from Pseudomonas sp.
PFams: Aldedh
498 amino acids: PaperBLAST, CDD, Compare to cluster

P42412 (methyl)malonate-semialdehyde dehydrogenase monomer (EC 1.2.1.27; EC 1.2.1.18) from Bacillus subtilis (strain 168)
IOLA_BACSU / P42412 Malonate-semialdehyde dehydrogenase; MSA dehydrogenase; Methylmalonate-semialdehyde dehydrogenase; MMSA dehydrogenase; MMSDH; MSDH; EC 1.2.1.-; EC 1.2.1.27 from Bacillus subtilis (strain 168)
P42412 methylmalonate-semialdehyde dehydrogenase (CoA-acylating) (EC 1.2.1.27) from Bacillus subtilis
PFams: Aldedh
487 amino acids: PaperBLAST, CDD, Compare to cluster

MMSA_HUMAN / Q02252 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; MMSDH; Malonate-semialdehyde dehydrogenase [acylating]; Aldehyde dehydrogenase family 6 member A1; EC 1.2.1.18; EC 1.2.1.27 from Homo sapiens (Human)
Q02252 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18); methylmalonate-semialdehyde dehydrogenase (CoA-acylating) (EC 1.2.1.27) from Homo sapiens
PFams: Aldedh
535 amino acids: PaperBLAST, CDD, Compare to cluster

Q9EQ20 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) from Mus musculus
PFams: Aldedh
535 amino acids: PaperBLAST, CDD, Compare to cluster

MMSA_RAT / Q02253 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; MMSDH; Malonate-semialdehyde dehydrogenase [acylating]; Aldehyde dehydrogenase family 6 member A1; EC 1.2.1.18; EC 1.2.1.27 from Rattus norvegicus (Rat)
PFams: Aldedh
535 amino acids: PaperBLAST, CDD, Compare to cluster

C8YX90 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) from Halomonas sp. HTNK1
PFams: Aldedh
503 amino acids: PaperBLAST, CDD, Compare to cluster

A0A1D8PM94 malonate semialdehyde dehydrogenase (CoA-acylating) (EC 1.2.1.18) from Candida albicans (strain SC5314 / ATCC MYA-2876)
PFams: Aldedh
541 amino acids: PaperBLAST, CDD, Compare to cluster

SMc00781 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) from Sinorhizobium meliloti 1021
PFams: Aldedh
498 amino acids: PaperBLAST, CDD, Compare to cluster

PS417_10925 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) from Pseudomonas simiae WCS417
PFams: Aldedh
499 amino acids: PaperBLAST, CDD, Compare to cluster

AO356_23175 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) from Pseudomonas fluorescens FW300-N2C3
PFams: Aldedh
500 amino acids: PaperBLAST, CDD, Compare to cluster

Pf6N2E2_515 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) from Pseudomonas fluorescens FW300-N2E2
PFams: Aldedh
500 amino acids: PaperBLAST, CDD, Compare to cluster