GapMind for catabolism of small carbon sources

 

Other Characterized Proteins Similar to mcm-small

Finding the characterized proteins for mcm-small (methylmalonyl-CoA mutase, small (adenosylcobamide-binding) subunit) in L-threonine catabolism

Or see clustering for step mcm-small

Or see all steps for L-threonine catabolism

Or cluster curated proteins matching a keyword

Definition of mcm-small

Fetched 2 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 17 other characterized sequences. (Found 19 hits including self hits.)

Removing ignored items reduces this to 6 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for mcm-small.)

I3VE74 2-hydroxyisobutanoyl-CoA mutase (subunit 1/2) (EC 5.4.99.64) from Aquincola tertiaricarbonis
I3VE74 2-hydroxyisobutanoyl-CoA mutase small subunit (EC 5.4.99.64) from Aquincola tertiaricarbonis
PFams: B12-binding
Heteromeric, 136 amino acids: PaperBLAST, CDD, metacyc::MONOMER-19835
54% identical to

O58013 methylmalonyl-CoA mutase (subunit 1/2) (EC 5.4.99.2) from Pyrococcus horikoshii
PFams: B12-binding
Heteromeric, 147 amino acids: PaperBLAST, CDD

D5WTR8 2-hydroxyisobutanoyl-CoA mutase (subunit 1/2) (EC 5.4.99.64) from Kyrpidia tusciae DSM 2912
PFams: B12-binding
Heteromeric, 132 amino acids: PaperBLAST, CDD, BRENDA::D5WTR8
50% identical to

O58013 methylmalonyl-CoA mutase (subunit 1/2) (EC 5.4.99.2) from Pyrococcus horikoshii
PFams: B12-binding
Heteromeric, 147 amino acids: PaperBLAST, CDD

PCMB_XANP2 / A7IQE6 Pivalyl-CoA mutase small subunit; PCM small subunit; Pivalyl-CoA mutase, AdoCbl-binding subunit; EC 5.4.99.- from Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2)
PFams: B12-binding
148 amino acids: PaperBLAST, CDD, SwissProt::A7IQE6
46% identical to

A4YIE3 methylmalonyl-CoA mutase (subunit 1/2) (EC 5.4.99.2) from Metallosphaera sedula
PFams: B12-binding
Heteromeric, 155 amino acids: PaperBLAST, CDD

ECM_RHOS4 / Q3IZ90 Ethylmalonyl-CoA mutase; EC 5.4.99.63 from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Q3IZ90 ethylmalonyl-CoA mutase (EC 5.4.99.63) from Rhodobacter sphaeroides
PFams: MM_CoA_mutase, B12-binding
652 amino acids: PaperBLAST, CDD, BRENDA::Q3IZ90
43% identical to

A4YIE3 methylmalonyl-CoA mutase (subunit 1/2) (EC 5.4.99.2) from Metallosphaera sedula
PFams: B12-binding
Heteromeric, 155 amino acids: PaperBLAST, CDD

C7C6S9 ethylmalonyl-CoA mutase (EC 5.4.99.63) from Methylorubrum extorquens
PFams: MM_CoA_mutase, B12-binding
688 amino acids: PaperBLAST, CDD, BRENDA::C7C6S9
46% identical to

O58013 methylmalonyl-CoA mutase (subunit 1/2) (EC 5.4.99.2) from Pyrococcus horikoshii
PFams: B12-binding
Heteromeric, 147 amino acids: PaperBLAST, CDD

ECM_METEA / Q49115 Ethylmalonyl-CoA mutase; EC 5.4.99.63 from Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1) (Methylobacterium extorquens)
PFams: MM_CoA_mutase, B12-binding
688 amino acids: PaperBLAST, CDD, SwissProt::Q49115
46% identical to

O58013 methylmalonyl-CoA mutase (subunit 1/2) (EC 5.4.99.2) from Pyrococcus horikoshii
PFams: B12-binding
Heteromeric, 147 amino acids: PaperBLAST, CDD

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for mcm-small.)

MCM_RHIME / O86028 Methylmalonyl-CoA mutase; MCM; EC 5.4.99.2 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
PFams: MM_CoA_mutase, B12-binding
712 amino acids: PaperBLAST, CDD, SwissProt::O86028
50% identical to

A4YIE3 methylmalonyl-CoA mutase (subunit 1/2) (EC 5.4.99.2) from Metallosphaera sedula
PFams: B12-binding
Heteromeric, 155 amino acids: PaperBLAST, CDD

A9WI23 methylmalonyl-CoA mutase large subunit (EC 5.4.99.2) from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
PFams: MM_CoA_mutase, B12-binding
Heteromeric, 733 amino acids: PaperBLAST, CDD, metacyc::MONOMER-17290
49% identical to

O58013 methylmalonyl-CoA mutase (subunit 1/2) (EC 5.4.99.2) from Pyrococcus horikoshii
PFams: B12-binding
Heteromeric, 147 amino acids: PaperBLAST, CDD

MUTA_HUMAN / P22033 Methylmalonyl-CoA mutase, mitochondrial; MCM; Methylmalonyl-CoA isomerase; EC 5.4.99.2 from Homo sapiens (Human)
P22033 methylmalonyl-CoA mutase (EC 5.4.99.2) from Homo sapiens
P22033 Methylmalonyl-CoA mutase, mitochondrial (EC 5.4.99.2) from Homo sapiens
PFams: MM_CoA_mutase, B12-binding
750 amino acids: PaperBLAST, CDD, BRENDA::P22033
40% identical to

O58013 methylmalonyl-CoA mutase (subunit 1/2) (EC 5.4.99.2) from Pyrococcus horikoshii
PFams: B12-binding
Heteromeric, 147 amino acids: PaperBLAST, CDD

Q23381 methylmalonyl-CoA mutase (EC 5.4.99.2) from Caenorhabditis elegans
PFams: MM_CoA_mutase, B12-binding
744 amino acids: PaperBLAST, CDD, BRENDA::Q23381
42% identical to

O58013 methylmalonyl-CoA mutase (subunit 1/2) (EC 5.4.99.2) from Pyrococcus horikoshii
PFams: B12-binding
Heteromeric, 147 amino acids: PaperBLAST, CDD

F1KUP0 methylmalonyl-CoA mutase subunit (EC 5.4.99.2) from Ascaris suum
PFams: MM_CoA_mutase, B12-binding
748 amino acids: PaperBLAST, CDD, metacyc::MONOMER-18293
40% identical to

O58013 methylmalonyl-CoA mutase (subunit 1/2) (EC 5.4.99.2) from Pyrococcus horikoshii
PFams: B12-binding
Heteromeric, 147 amino acids: PaperBLAST, CDD

b2917 methylmalonyl-CoA mutase (EC 5.4.99.2) from Escherichia coli K-12 substr. MG1655
SCPA_ECOLI / P27253 Methylmalonyl-CoA mutase; MCM; EC 5.4.99.2 from Escherichia coli (strain K12)
P27253 methylmalonyl-CoA mutase (EC 5.4.99.2) from Escherichia coli (strain K12)
PFams: MM_CoA_mutase, B12-binding
714 amino acids: PaperBLAST, CDD, SwissProt::P27253
43% identical to

O58013 methylmalonyl-CoA mutase (subunit 1/2) (EC 5.4.99.2) from Pyrococcus horikoshii
PFams: B12-binding
Heteromeric, 147 amino acids: PaperBLAST, CDD

MCM_RHOS4 / Q3J4D7 Methylmalonyl-CoA mutase; MCM; EC 5.4.99.2 from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Q3J4D7 methylmalonyl-CoA mutase (EC 5.4.99.2) from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
PFams: MM_CoA_mutase, B12-binding
709 amino acids: PaperBLAST, CDD, SwissProt::Q3J4D7
43% identical to

O58013 methylmalonyl-CoA mutase (subunit 1/2) (EC 5.4.99.2) from Pyrococcus horikoshii
PFams: B12-binding
Heteromeric, 147 amino acids: PaperBLAST, CDD

Q84FZ1 methylmalonyl-CoA mutase (EC 5.4.99.2) from Methylorubrum extorquens
PFams: MM_CoA_mutase, B12-binding
721 amino acids: PaperBLAST, CDD, BRENDA::Q84FZ1
43% identical to

A4YIE3 methylmalonyl-CoA mutase (subunit 1/2) (EC 5.4.99.2) from Metallosphaera sedula
PFams: B12-binding
Heteromeric, 155 amino acids: PaperBLAST, CDD

Dsui_0519 Methylmalonyl-CoA mutase (EC 5.4.99.2) from Dechlorosoma suillum PS
PFams: MM_CoA_mutase, B12-binding
721 amino acids: PaperBLAST, CDD, reanno::PS:Dsui_0519
43% identical to

A4YIE3 methylmalonyl-CoA mutase (subunit 1/2) (EC 5.4.99.2) from Metallosphaera sedula
PFams: B12-binding
Heteromeric, 155 amino acids: PaperBLAST, CDD

MUTB_PROFR / P11653 Methylmalonyl-CoA mutase large subunit; MCM-alpha; EC 5.4.99.2 from Propionibacterium freudenreichii subsp. shermanii
P11653 methylmalonyl-CoA mutase (EC 5.4.99.2) from Propionibacterium freudenreichii subsp. shermanii
P11653 methylmalonyl-CoA mutase large subunit (EC 5.4.99.2) from Propionibacterium freudenreichii subsp. shermanii
PFams: MM_CoA_mutase, B12-binding
Heteromeric, 728 amino acids: PaperBLAST, CDD, BRENDA::P11653
42% identical to

A4YIE3 methylmalonyl-CoA mutase (subunit 1/2) (EC 5.4.99.2) from Metallosphaera sedula
PFams: B12-binding
Heteromeric, 155 amino acids: PaperBLAST, CDD

Q8MI68 methylmalonyl-CoA mutase (EC 5.4.99.2) from Sus scrofa
PFams: MM_CoA_mutase, B12-binding
750 amino acids: PaperBLAST, CDD, BRENDA::Q8MI68
41% identical to

A4YIE3 methylmalonyl-CoA mutase (subunit 1/2) (EC 5.4.99.2) from Metallosphaera sedula
PFams: B12-binding
Heteromeric, 155 amino acids: PaperBLAST, CDD