GapMind for catabolism of small carbon sources

 

Other Characterized Proteins Similar to mcmA

Finding the characterized proteins for mcmA (methylmalonyl-CoA mutase, fused catalytic and adenosylcobamide-binding components) in L-threonine catabolism

Or see clustering for step mcmA

Or see all steps for L-threonine catabolism

Or cluster curated proteins matching a keyword

Definition of mcmA

Fetched 11 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 9 other characterized sequences. (Found 20 hits including self hits.)

Removing ignored items reduces this to 5 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for mcmA.)

ICMF_CUPMC / Q1LRY0 Fused isobutyryl-CoA mutase; EC 5.4.99.13; EC 3.6.5.- from Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34) (Ralstonia metallidurans)
Q1LRY0 isobutyryl-CoA mutase (EC 5.4.99.13) from Cupriavidus metallidurans
PFams: B12-binding, MeaB, cobW, MM_CoA_mutase
1093 amino acids: PaperBLAST, CDD, SwissProt::Q1LRY0
83% identical to

Q8Y2U5 methylmalonyl-CoA mutase (EC 5.4.99.2) from Ralstonia solanacearum
PFams: B12-binding, MeaB, cobW, MM_CoA_mutase
1099 amino acids: PaperBLAST, CDD

ICMF_NOCFA / Q5Z110 Fused isobutyryl-CoA mutase; EC 5.4.99.13; EC 3.6.5.- from Nocardia farcinica (strain IFM 10152)
PFams: B12-binding, MeaB, MM_CoA_mutase
1071 amino acids: PaperBLAST, CDD, SwissProt::Q5Z110
68% identical to

Q8Y2U5 methylmalonyl-CoA mutase (EC 5.4.99.2) from Ralstonia solanacearum
PFams: B12-binding, MeaB, cobW, MM_CoA_mutase
1099 amino acids: PaperBLAST, CDD

ICMF_GEOKA / Q5KUG0 Fused isobutyryl-CoA mutase; EC 5.4.99.13; EC 3.6.5.- from Geobacillus kaustophilus (strain HTA426)
PFams: B12-binding, MeaB, cobW, MM_CoA_mutase
1086 amino acids: PaperBLAST, CDD, SwissProt::Q5KUG0
62% identical to

Q8Y2U5 methylmalonyl-CoA mutase (EC 5.4.99.2) from Ralstonia solanacearum
PFams: B12-binding, MeaB, cobW, MM_CoA_mutase
1099 amino acids: PaperBLAST, CDD

I3VE77 2-hydroxyisobutanoyl-CoA mutase (subunit 2/2) (EC 5.4.99.64) from Aquincola tertiaricarbonis
I3VE77 2-hydroxyisobutanoyl-CoA mutase large subunit (EC 5.4.99.64) from Aquincola tertiaricarbonis
PFams: MM_CoA_mutase
Heteromeric, 562 amino acids: PaperBLAST, CDD, metacyc::MONOMER-19834
45% identical to

MCM_RHOS4 / Q3J4D7 Methylmalonyl-CoA mutase; MCM; EC 5.4.99.2 from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Q3J4D7 methylmalonyl-CoA mutase (EC 5.4.99.2) from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
PFams: MM_CoA_mutase, B12-binding
709 amino acids: PaperBLAST, CDD

D5WTR7 2-hydroxyisobutanoyl-CoA mutase (subunit 2/2) (EC 5.4.99.64) from Kyrpidia tusciae DSM 2912
PFams: MM_CoA_mutase
Heteromeric, 563 amino acids: PaperBLAST, CDD, BRENDA::D5WTR7
40% identical to

MCM_RHOS4 / Q3J4D7 Methylmalonyl-CoA mutase; MCM; EC 5.4.99.2 from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Q3J4D7 methylmalonyl-CoA mutase (EC 5.4.99.2) from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
PFams: MM_CoA_mutase, B12-binding
709 amino acids: PaperBLAST, CDD

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for mcmA.)

A9WI23 methylmalonyl-CoA mutase large subunit (EC 5.4.99.2) from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
PFams: MM_CoA_mutase, B12-binding
Heteromeric, 733 amino acids: PaperBLAST, CDD, metacyc::MONOMER-17290
68% identical to

Q84FZ1 methylmalonyl-CoA mutase (EC 5.4.99.2) from Methylorubrum extorquens
PFams: MM_CoA_mutase, B12-binding
721 amino acids: PaperBLAST, CDD

MUTB_PROFR / P11653 Methylmalonyl-CoA mutase large subunit; MCM-alpha; EC 5.4.99.2 from Propionibacterium freudenreichii subsp. shermanii
P11653 methylmalonyl-CoA mutase (EC 5.4.99.2) from Propionibacterium freudenreichii subsp. shermanii
P11653 methylmalonyl-CoA mutase large subunit (EC 5.4.99.2) from Propionibacterium freudenreichii subsp. shermanii
PFams: MM_CoA_mutase, B12-binding
Heteromeric, 728 amino acids: PaperBLAST, CDD, BRENDA::P11653
69% identical to

Q84FZ1 methylmalonyl-CoA mutase (EC 5.4.99.2) from Methylorubrum extorquens
PFams: MM_CoA_mutase, B12-binding
721 amino acids: PaperBLAST, CDD

O74009 methylmalonyl-CoA mutase (subunit 2/2) (EC 5.4.99.2) from Pyrococcus horikoshii
PFams: MM_CoA_mutase
Heteromeric, 563 amino acids: PaperBLAST, CDD, BRENDA::O74009
51% identical to

MCM_RHOS4 / Q3J4D7 Methylmalonyl-CoA mutase; MCM; EC 5.4.99.2 from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Q3J4D7 methylmalonyl-CoA mutase (EC 5.4.99.2) from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
PFams: MM_CoA_mutase, B12-binding
709 amino acids: PaperBLAST, CDD

A4YEG1 methylmalonyl-CoA mutase (subunit 2/2) (EC 5.4.99.2) from Metallosphaera sedula
PFams: MM_CoA_mutase
Heteromeric, 553 amino acids: PaperBLAST, CDD, BRENDA::A4YEG1
48% identical to

MCM_RHOS4 / Q3J4D7 Methylmalonyl-CoA mutase; MCM; EC 5.4.99.2 from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Q3J4D7 methylmalonyl-CoA mutase (EC 5.4.99.2) from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
PFams: MM_CoA_mutase, B12-binding
709 amino acids: PaperBLAST, CDD