Finding the characterized proteins for serP1 (L-threonine uptake transporter SerP1) in L-threonine catabolism
Or see clustering for step serP1
Or see all steps for L-threonine catabolism
Or cluster curated proteins matching a keyword
Definition of serP1
Fetched 1 sequences
Running ublast to find other characterized proteins with 40% identity and 70% coverage
Found hits to 5 other characterized sequences. (Found 6 hits including self hits.)
Removing ignored items reduces this to 4 close sequences.
(Sequences that are similar to these will not be high-confidence candidates for serP1.)
SERP2_LACLM / A2RI86 DL-alanine permease SerP2 from Lactococcus lactis subsp. cremoris (strain MG1363)
PFams: AA_permease, AA_permease_2
460 amino acids: PaperBLAST, CDD, SwissProt::A2RI86
62% identical to
TC 2.A.3.1.21 / F2HQ25 Serine uptake transporter, SerP1, of 259 aas and 12 TMSs (Trip et al. 2013). L-serine is the highest affinity substrate (Km = 18 μM), but SerP1 also transports L-threonine and L-cysteine (Km values = 20 - 40 μM) from Lactococcus lactis subsp. lactis (strain CV56)
PFams: AA_permease, AA_permease_2
459 amino acids: PaperBLAST, CDD
TC 2.A.3.1.20 / F2HQ24 Serine transporter, SerP2 or YdgB, of 459 aas and 12 TMSs (Trip et al. 2013). Transports L-alanine (Km = 20 μM), D-alanine (Km = 38 μM), L-serine, D-serine (Km = 356 μM) and glycine (Noens and Lolkema 2015). The encoding gene is adjacent to the one encoding SerP1 (TC# 2.A.3.1.21) from Lactococcus lactis subsp. lactis (strain CV56)
PFams: AA_permease, AA_permease_2
457 amino acids: PaperBLAST, CDD, TCDB::F2HQ24
62% identical to
TC 2.A.3.1.21 / F2HQ25 Serine uptake transporter, SerP1, of 259 aas and 12 TMSs (Trip et al. 2013). L-serine is the highest affinity substrate (Km = 18 μM), but SerP1 also transports L-threonine and L-cysteine (Km values = 20 - 40 μM) from Lactococcus lactis subsp. lactis (strain CV56)
PFams: AA_permease, AA_permease_2
459 amino acids: PaperBLAST, CDD
b4208 D-serine/alanine/glycine/:H+symporter from Escherichia coli K-12 substr. MG1655
P0AAE0 D-serine/alanine/glycine/:H+symporter from Escherichia coli (strain K12)
CYCA_ECOLI / P0AAE0 D-serine/D-alanine/glycine transporter from Escherichia coli (strain K12)
TC 2.A.3.1.7 / P0AAE0 D-Serine/D-alanine/glycine/D-cycloserine:H+ symporter from Escherichia coli
PFams: AA_permease, AA_permease_2
470 amino acids: PaperBLAST, CDD, SwissProt::P0AAE0
40% identical to
TC 2.A.3.1.21 / F2HQ25 Serine uptake transporter, SerP1, of 259 aas and 12 TMSs (Trip et al. 2013). L-serine is the highest affinity substrate (Km = 18 μM), but SerP1 also transports L-threonine and L-cysteine (Km values = 20 - 40 μM) from Lactococcus lactis subsp. lactis (strain CV56)
PFams: AA_permease, AA_permease_2
459 amino acids: PaperBLAST, CDD
CYCA_ECOL6 / A0A0H2VDI7 D-serine/D-alanine/glycine transporter from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
PFams: AA_permease, AA_permease_2
470 amino acids: PaperBLAST, CDD, SwissProt::A0A0H2VDI7
40% identical to
TC 2.A.3.1.21 / F2HQ25 Serine uptake transporter, SerP1, of 259 aas and 12 TMSs (Trip et al. 2013). L-serine is the highest affinity substrate (Km = 18 μM), but SerP1 also transports L-threonine and L-cysteine (Km values = 20 - 40 μM) from Lactococcus lactis subsp. lactis (strain CV56)
PFams: AA_permease, AA_permease_2
459 amino acids: PaperBLAST, CDD
(Sequences that are similar to these will still be high-confidence candidates for serP1.)
SERP1_LACLM / A2RI87 Serine permease SerP1 from Lactococcus lactis subsp. cremoris (strain MG1363)
PFams: AA_permease, AA_permease_2
459 amino acids: PaperBLAST, CDD, SwissProt::A2RI87
94% identical to
TC 2.A.3.1.21 / F2HQ25 Serine uptake transporter, SerP1, of 259 aas and 12 TMSs (Trip et al. 2013). L-serine is the highest affinity substrate (Km = 18 μM), but SerP1 also transports L-threonine and L-cysteine (Km values = 20 - 40 μM) from Lactococcus lactis subsp. lactis (strain CV56)
PFams: AA_permease, AA_permease_2
459 amino acids: PaperBLAST, CDD