GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for tdh (L-threonine 3-dehydrogenase) in L-threonine catabolism

Or see other characterized proteins similar to tdh

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Definition of tdh

Fetched 12 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 11 of these sequences

Found 2 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 341-350 amino acids (not heteromeric)

TDH_PYRHO / O58389 L-threonine 3-dehydrogenase; L-ThrDH; TDH; L-threonine dehydrogenase; EC 1.1.1.103 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
O58389 L-threonine 3-dehydrogenase (EC 1.1.1.103) from Pyrococcus horikoshii
PFams: ADH_N, Glu_dehyd_C, ADH_zinc_N, ADH_zinc_N_2
348 amino acids: PaperBLAST, CDD, Compare to cluster

b3616 threonine dehydrogenase (EC 1.1.1.103) from Escherichia coli K-12 substr. MG1655
P07913 threonine dehydrogenase (EC 1.1.1.103) from Escherichia coli (strain K12)
TDH_ECOLI / P07913 L-threonine 3-dehydrogenase; TDH; L-threonine dehydrogenase; EC 1.1.1.103 from Escherichia coli (strain K12)
P07913 L-threonine 3-dehydrogenase (EC 1.1.1.103) from Escherichia coli
PFams: ADH_N, ADH_zinc_N
341 amino acids: PaperBLAST, CDD, Compare to cluster

TDH_THEKO / Q5JI69 L-threonine 3-dehydrogenase; TDH; L-threonine dehydrogenase; EC 1.1.1.103 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
Q5JI69 L-threonine 3-dehydrogenase (EC 1.1.1.103) from Thermococcus kodakarensis
PFams: ADH_N, Glu_dehyd_C, ADH_zinc_N, ADH_zinc_N_2
350 amino acids: PaperBLAST, CDD, Compare to cluster

TDH_THET8 / Q5SKS4 L-threonine 3-dehydrogenase; TDH; EC 1.1.1.103 from Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
PFams: ADH_N, ADH_zinc_N
343 amino acids: PaperBLAST, CDD, Compare to cluster

TDH_PYRFU / Q8U259 L-threonine 3-dehydrogenase; TDH; L-threonine dehydrogenase; EC 1.1.1.103 from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Q8U259 alcohol dehydrogenase (EC 1.1.1.1) from Pyrococcus furiosus
PFams: ADH_N, Glu_dehyd_C, ADH_zinc_N, ADH_zinc_N_2
348 amino acids: PaperBLAST, CDD, Compare to cluster

PGA1_c34320 L-threonine 3-dehydrogenase (EC 1.1.1.103) from Phaeobacter inhibens BS107
PFams: ADH_N, Glu_dehyd_C, ADH_zinc_N
342 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 318-373 amino acids (not heteromeric)

E3PS87 L-threonine 3-dehydrogenase (EC 1.1.1.103) from Acetoanaerobium sticklandii
PFams: RmlD_sub_bind, Epimerase, Polysacc_synt_2, 3Beta_HSD, GDP_Man_Dehyd, NAD_binding_4
319 amino acids: PaperBLAST, CDD, Compare to cluster

E5RQ20 L-threonine 3-dehydrogenase (EC 1.1.1.103) from Cupriavidus necator
PFams: RmlD_sub_bind, Epimerase, GDP_Man_Dehyd
318 amino acids: PaperBLAST, CDD, Compare to cluster

TDH_MOUSE / Q8K3F7 L-threonine 3-dehydrogenase, mitochondrial; EC 1.1.1.103 from Mus musculus (Mouse)
Q8K3F7 L-threonine 3-dehydrogenase (EC 1.1.1.103) from Mus musculus
PFams: RmlD_sub_bind, Epimerase, 3Beta_HSD, GDP_Man_Dehyd
373 amino acids: PaperBLAST, CDD, Compare to cluster

TDH_PIG / Q8MIR0 L-threonine 3-dehydrogenase, mitochondrial; EC 1.1.1.103 from Sus scrofa (Pig)
PFams: RmlD_sub_bind, Epimerase, 3Beta_HSD, GDP_Man_Dehyd, NAD_binding_4
373 amino acids: PaperBLAST, CDD, Compare to cluster

RR42_RS28300 L-threonine 3-dehydrogenase (EC 1.1.1.103) from Cupriavidus basilensis 4G11
PFams: RmlD_sub_bind, Epimerase, 3Beta_HSD, GDP_Man_Dehyd, Polysacc_synt_2, NAD_binding_4
324 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/1 heteromeric)

b3589 L-threonine dehydrogenase (EC 1.1.1.103) from Escherichia coli K-12 substr. MG1655
P37686 L-threonine dehydrogenase (EC 1.1.1.103) from Escherichia coli (strain K12)
PFams: Fe-ADH, Fe-ADH_2
383 amino acids: PaperBLAST, CDD