GapMind for catabolism of small carbon sources

 

Other Characterized Proteins Similar to Slc28a3

Finding the characterized proteins for Slc28a3 (thymidine:Na+ symporter SLC28A3) in thymidine catabolism

Or see clustering for step Slc28a3

Or see all steps for thymidine catabolism

Or cluster curated proteins matching a keyword

Definition of Slc28a3

Fetched 1 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 7 other characterized sequences. (Found 8 hits including self hits.)

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for Slc28a3.)

TC 2.A.41.2.6 / Q9ERH8 Broad-specificity nucleoside:Na+, H+ and Li+ symporter, hCNT3 (Slc28a3) transports a broad range of both purine and pyrimidine nucleosides as well as anticancer and antiviral nucleoside drugs, but guanosine, 3'azido-3-deoxythymidine and 2',3'-dideoxycytidine, which are substrates with Na+, are not substrates with H+. Both of the two cation-binding sites can apparently bind Na+, but only one can bind H+, and the Na+ and H+ forms transport different ranges of substrates. (Note: Cnt1 and Cnt2 are Na+-specific.) from Homo sapiens (Human)
RF|NP_071712.3 solute carrier family 28 member 3 from Mus musculus
PFams: Nucleos_tra2_N, Gate, Nucleos_tra2_C
703 amino acids: PaperBLAST, CDD, CharProtDB::CH_091498
55% identical to

TC 2.A.41.2.5 / Q9UA35 Broadly selective nucleoside:Na+ cotransporter, hfCNT (transports uridine, thymidine, inosine, 3'-azido-3'deoxythymidine, 2'3'dideoxycytidine, and 2'3'dideoxyinosine) (Na+/uridine = 2) from Eptatretus stoutii (Pacific hagfish)
PFams: Nucleos_tra2_N, Gate, Nucleos_tra2_C
683 amino acids: PaperBLAST, CDD

S28A3_RAT / Q8VIH3 Solute carrier family 28 member 3; Concentrative Na(+)-nucleoside cotransporter 3; CNT 3; rCNT3 from Rattus norvegicus (Rat)
PFams: Nucleos_tra2_N, Gate, Nucleos_tra2_C
705 amino acids: PaperBLAST, CDD, SwissProt::Q8VIH3
55% identical to

TC 2.A.41.2.5 / Q9UA35 Broadly selective nucleoside:Na+ cotransporter, hfCNT (transports uridine, thymidine, inosine, 3'-azido-3'deoxythymidine, 2'3'dideoxycytidine, and 2'3'dideoxyinosine) (Na+/uridine = 2) from Eptatretus stoutii (Pacific hagfish)
PFams: Nucleos_tra2_N, Gate, Nucleos_tra2_C
683 amino acids: PaperBLAST, CDD

S28A3_HUMAN / Q9HAS3 Solute carrier family 28 member 3; Concentrative Na(+)-nucleoside cotransporter 3; CNT 3; hCNT3 from Homo sapiens (Human)
TC 2.A.41.2.8 / Q9HAS3 Solute carrier family 28 member 3 (Concentrative Na+-nucleoside cotransporter 3) (CNT 3) (hCNT3) from Homo sapiens
PFams: Nucleos_tra2_N, Gate, Nucleos_tra2_C
691 amino acids: PaperBLAST, CDD, SwissProt::Q9HAS3
53% identical to

TC 2.A.41.2.5 / Q9UA35 Broadly selective nucleoside:Na+ cotransporter, hfCNT (transports uridine, thymidine, inosine, 3'-azido-3'deoxythymidine, 2'3'dideoxycytidine, and 2'3'dideoxyinosine) (Na+/uridine = 2) from Eptatretus stoutii (Pacific hagfish)
PFams: Nucleos_tra2_N, Gate, Nucleos_tra2_C
683 amino acids: PaperBLAST, CDD

TC 2.A.41.2.1 / Q62773 Purine-specific nucleoside:Na+ symporter
PFams: Nucleos_tra2_N, Gate, Nucleos_tra2_C
659 amino acids: PaperBLAST, CDD, TCDB::Q62773
47% identical to

TC 2.A.41.2.5 / Q9UA35 Broadly selective nucleoside:Na+ cotransporter, hfCNT (transports uridine, thymidine, inosine, 3'-azido-3'deoxythymidine, 2'3'dideoxycytidine, and 2'3'dideoxyinosine) (Na+/uridine = 2) from Eptatretus stoutii (Pacific hagfish)
PFams: Nucleos_tra2_N, Gate, Nucleos_tra2_C
683 amino acids: PaperBLAST, CDD

S28A1_RAT / Q62674 Sodium/nucleoside cotransporter 1; Concentrative nucleoside transporter 1; CNT 1; Na(+)/nucleoside cotransporter 1; Sodium-coupled nucleoside transporter 1; Solute carrier family 28 member 1 from Rattus norvegicus (Rat)
TC 2.A.41.2.2 / Q62674 Nonspecific nucleoside:Na+ symporter from Rattus norvegicus (Rat)
RF|NP_446315.1 sodium/nucleoside cotransporter 1 from Rattus norvegicus
PFams: Nucleos_tra2_N, Gate, Nucleos_tra2_C
648 amino acids: PaperBLAST, CDD, SwissProt::Q62674
48% identical to

TC 2.A.41.2.5 / Q9UA35 Broadly selective nucleoside:Na+ cotransporter, hfCNT (transports uridine, thymidine, inosine, 3'-azido-3'deoxythymidine, 2'3'dideoxycytidine, and 2'3'dideoxyinosine) (Na+/uridine = 2) from Eptatretus stoutii (Pacific hagfish)
PFams: Nucleos_tra2_N, Gate, Nucleos_tra2_C
683 amino acids: PaperBLAST, CDD

TC 2.A.41.2.4 / O43868 Purine nucleoside, uridine, and 2'3'dideoxyinosine cladribrine:Na+ symporter, CNT2 (Na+/nucleoside = 1) from Homo sapiens (Human)
PFams: Nucleos_tra2_N, Gate, Nucleos_tra2_C
658 amino acids: PaperBLAST, CDD, TCDB::O43868
46% identical to

TC 2.A.41.2.5 / Q9UA35 Broadly selective nucleoside:Na+ cotransporter, hfCNT (transports uridine, thymidine, inosine, 3'-azido-3'deoxythymidine, 2'3'dideoxycytidine, and 2'3'dideoxyinosine) (Na+/uridine = 2) from Eptatretus stoutii (Pacific hagfish)
PFams: Nucleos_tra2_N, Gate, Nucleos_tra2_C
683 amino acids: PaperBLAST, CDD

S28A1_HUMAN / O00337 Sodium/nucleoside cotransporter 1; Concentrative nucleoside transporter 1; CNT 1; hCNT1; Na(+)/nucleoside cotransporter 1; Sodium-coupled nucleoside transporter 1; Solute carrier family 28 member 1 from Homo sapiens (Human)
TC 2.A.41.2.3 / O00337 Pyrimidine-preferring nucleoside:Na+ symporter, CNT1 (Na+/nucleoside = 2)(transports uridine, gemcitabine and 5'-deoxy-5'-fluorouridine) (Larráyoz et al., 2004), but in addition to pyrimidine nucelosides, it transports adenosine from Homo sapiens (Human)
PFams: Nucleos_tra2_N, Gate, Nucleos_tra2_C
649 amino acids: PaperBLAST, CDD, SwissProt::O00337
48% identical to

TC 2.A.41.2.5 / Q9UA35 Broadly selective nucleoside:Na+ cotransporter, hfCNT (transports uridine, thymidine, inosine, 3'-azido-3'deoxythymidine, 2'3'dideoxycytidine, and 2'3'dideoxyinosine) (Na+/uridine = 2) from Eptatretus stoutii (Pacific hagfish)
PFams: Nucleos_tra2_N, Gate, Nucleos_tra2_C
683 amino acids: PaperBLAST, CDD