Clusters of Characterized Proteins

GapMind for catabolism of small carbon sources

Clusters of Characterized Proteins

Clustering the characterized proteins for ald-dh-CoA (acetaldehyde dehydrogenase, acylating) in thymidine catabolism

Or see other characterized proteins similar to ald-dh-CoA

Or see all steps for thymidine catabolism

Or cluster curated proteins matching a keyword

Definition of ald-dh-CoA

Curated proteins or TIGRFams with EC 1.2.1.10
Ignore hits to items matching 1.1.1.1 when looking for 'other' hits
Ignore hits to items matching 1.1.1.71 when looking for 'other' hits
Ignore hits to items matching 1.2.1.57 when looking for 'other' hits
Ignore hits to Q2XQZ7 when looking for 'other' hits (4-hydroxy-2-oxovalerate aldolase (EC 4.1.3.39))
Comment: Many enzymes are multifunctional alcohol/acetaldehyde dehydrogenases, and many close homologs have just one annotation. EC 1.2.1.57 is acylating butanal dehydrogenase, which may also act on acetaldehyde. Q2XQZ7 is probably misannotated.

Fetched 23 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 23 of these sequences

Found 3 clusters of similar sequences. Download as table or as draft rules or view by cluster

Anaerobium acetethylicum

A0A1D3TRQ6 acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Anaerobium acetethylicum
PFams: Aldedh, Fe-ADH, Fe-ADH_2, Fe-ADH_2
871 amino acids: PaperBLAST, CDD (Cluster 1)

Bilophila wadsworthia

E5Y379 acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Bilophila wadsworthia 3_1_6
PFams: Aldedh
484 amino acids: PaperBLAST, CDD (Cluster 3)

Chlamydomonas reinhardtii

A8JI07 alcohol dehydrogenase / acetaldehyde dehydrogenase (EC 1.2.1.10; EC 1.1.1.1) from Chlamydomonas reinhardtii
PFams: Aldedh, Fe-ADH, Fe-ADH_2
954 amino acids: PaperBLAST, CDD (Cluster 1)

Clostridium acetobutylicum

P33744 alcohol/aldehyde dehydrogenase (EC 1.1.1.1; EC 1.2.1.10; EC 1.2.1.57) from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
ADHE_CLOAB / P33744 Aldehyde-alcohol dehydrogenase; AAD; EC 1.1.1.1; EC 1.2.1.3 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
GB|AAD04638.1 aldehyde-alcohol dehydrogenase; EC 1.1.1.1; EC 1.2.1.10 from Clostridium acetobutylicum ATCC 824
PFams: Aldedh, Fe-ADH
862 amino acids: PaperBLAST, CDD (Cluster 1)

Comamonas testosteroni

Q83VZ4 propanal dehydrogenase (EC 1.2.1.87) (from HMM only) from Comamonas testosteroni
PFams: Semialdhyde_dh, AcetDehyd-dimer
307 amino acids: PaperBLAST, CDD (Cluster 2)

Entamoeba histolytica

ADH2_ENTHI / Q24803 Aldehyde-alcohol dehydrogenase 2; EC 1.1.1.1; EC 1.2.1.10 from Entamoeba histolytica
GB|AAA81906.1 aldehyde-alcohol dehydrogenase 2; EC 1.1.1.1; EC 1.2.1.10 from Entamoeba histolytica
PFams: Aldedh, Fe-ADH, Fe-ADH_2, Fe-ADH_2
870 amino acids: PaperBLAST, CDD (Cluster 1)

Escherichia coli

b0351 acetaldehyde dehydrogenase (acetylating) MhpF (EC 1.2.1.10) from Escherichia coli K-12 substr. MG1655
P77580 acetaldehyde dehydrogenase (acetylating) MhpF (EC 1.2.1.10) from Escherichia coli (strain K12)
ACDH_ECOLI / P77580 Acetaldehyde dehydrogenase; Acetaldehyde dehydrogenase [acetylating]; EC 1.2.1.10 from Escherichia coli (strain K12)
GB|AAZ87107.1 acetaldehyde dehydrogenase; EC 1.2.1.10 from Escherichia coli K12
PFams: Semialdhyde_dh, AcetDehyd-dimer
316 amino acids: PaperBLAST, CDD (Cluster 2)

b1241 aldehyde/alcohol dehydrogenase AdhE (EC 1.1.1.1; EC 1.2.1.10) from Escherichia coli K-12 substr. MG1655
P0A9Q7 aldehyde/alcohol dehydrogenase AdhE (EC 1.1.1.1; EC 1.2.1.10) from Escherichia coli (strain K12)
MB|P0A9Q7 aldehyde-alcohol dehydrogenase; EC 1.1.1.1; EC 1.2.1.10 from Escherichia coli K12
PFams: Aldedh, Fe-ADH, Fe-ADH_2
891 amino acids: PaperBLAST, CDD (Cluster 1)

b2455 acetaldehyde dehydrogenase (acetylating) EutE (EC 1.2.1.10) from Escherichia coli K-12 substr. MG1655
P77445 acetaldehyde dehydrogenase (acetylating) EutE (EC 1.2.1.10) from Escherichia coli (strain K12)
PFams: Aldedh
467 amino acids: PaperBLAST, CDD (Cluster 3)

Hungateiclostridium thermocellum

A0A0H3W5U9 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Hungateiclostridium thermocellum
A3DCI2 alcohol dehydrogenase (EC 1.1.1.1); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Hungateiclostridium thermocellum
PFams: Aldedh, Fe-ADH, Fe-ADH_2, Fe-ADH_2
873 amino acids: PaperBLAST, CDD (Cluster 1)

Mycobacterium tuberculosis

P9WQH3 propanal dehydrogenase (EC 1.2.1.87) (from HMM only) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PFams: Semialdhyde_dh, AcetDehyd-dimer
303 amino acids: PaperBLAST, CDD (Cluster 2)

Paraburkholderia xenovorans

ACDH4_PARXL / Q79AF6 Acetaldehyde dehydrogenase 4; Acetaldehyde dehydrogenase [acetylating] 4; Propanal dehydrogenase (CoA-propanoylating); EC 1.2.1.10; EC 1.2.1.87 from Paraburkholderia xenovorans (strain LB400)
Q79AF6 acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10); propanal dehydrogenase (CoA-propanoylating) (EC 1.2.1.87) from Paraburkholderia xenovorans
PFams: Semialdhyde_dh, AcetDehyd-dimer
Heteromeric, 304 amino acids: PaperBLAST, CDD (Cluster 2)

Polytomella Pringsheim

Q70YJ9 alcohol dehydrogenase (EC 1.1.1.1); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Polytomella sp. Pringsheim 198.80
PFams: Aldedh, Fe-ADH
885 amino acids: PaperBLAST, CDD (Cluster 1)

Pseudomonas

Q52060 acetaldehyde dehydrogenase (acylating) (EC 1.2.1.10) from Pseudomonas sp. (strain CF600)
ACDH_PSEUF / Q52060 Acetaldehyde dehydrogenase; Acetaldehyde dehydrogenase [acetylating]; EC 1.2.1.10 from Pseudomonas sp. (strain CF600)
Q52060 acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Pseudomonas sp.
PFams: Semialdhyde_dh, AcetDehyd-dimer
Heteromeric, 312 amino acids: PaperBLAST, CDD (Cluster 2)

ACDH_PSESP / Q9KWS1 Acetaldehyde dehydrogenase; Acetaldehyde dehydrogenase [acetylating]; EC 1.2.1.10 from Pseudomonas sp.
PFams: Semialdhyde_dh, AcetDehyd-dimer
316 amino acids: PaperBLAST, CDD (Cluster 2)

Pseudomonas (strain

Pseudomonas putida

Q51949 acylating aldehyde dehydrogenase (EC 1.2.1.10) from Pseudomonas putida
PFams: Semialdhyde_dh, AcetDehyd-dimer
316 amino acids: PaperBLAST, CDD (Cluster 2)

Rhodococcus jostii

Q0S816 propanal dehydrogenase (EC 1.2.1.87) (from HMM only) from Rhodococcus jostii (strain RHA1)
PFams: Semialdhyde_dh, AcetDehyd-dimer
300 amino acids: PaperBLAST, CDD (Cluster 2)

Salmonella typhimurium

P41793 acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
PFams: Aldedh
467 amino acids: PaperBLAST, CDD (Cluster 3)

Thermoanaerobacter

B0K315 acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Thermoanaerobacter sp.
PFams: Aldedh
466 amino acids: PaperBLAST, CDD (Cluster 3)

Thermoanaerobacter X514

B0K4A2 alcohol dehydrogenase (EC 1.1.1.1); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Thermoanaerobacter sp. X514
PFams: Aldedh, Fe-ADH, Fe-ADH_2, Fe-ADH_2
872 amino acids: PaperBLAST, CDD (Cluster 1)

Thermoanaerobacter ethanolicus

C7IV28 alcohol dehydrogenase (EC 1.1.1.1); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Thermoanaerobacter ethanolicus
PFams: Aldedh, Fe-ADH, Fe-ADH_2, Fe-ADH_2
872 amino acids: PaperBLAST, CDD (Cluster 1)

Thermoanaerobacterium saccharolyticum

A0A0H3W5K4 acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Thermoanaerobacterium saccharolyticum
I3VSF1 alcohol dehydrogenase (EC 1.1.1.1); L-lactate dehydrogenase (EC 1.1.1.27); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Thermoanaerobacterium saccharolyticum
PFams: Aldedh, Fe-ADH, Fe-ADH_2, Fe-ADH_2
859 amino acids: PaperBLAST, CDD (Cluster 1)

Thermus thermophilus

ACDH_THET8 / Q53WH9 Acetaldehyde dehydrogenase; Acetaldehyde dehydrogenase [acetylating]; Propanal dehydrogenase (CoA-propanoylating); Propanaldehyde dehydrogenase; EC 1.2.1.10; EC 1.2.1.87 from Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Q53WH9 acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10); propanal dehydrogenase (CoA-propanoylating) (EC 1.2.1.87) from Thermus thermophilus
PFams: GFO_IDH_MocA, Semialdhyde_dh, AcetDehyd-dimer
307 amino acids: PaperBLAST, CDD (Cluster 2)