GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for deoA (thymidine phosphorylase DeoA) in thymidine catabolism

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Definition of deoA

Fetched 15 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 14 of these sequences

Found 3 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 421-503 amino acids (not heteromeric)

TYPH_HUMAN / P19971 Thymidine phosphorylase; TP; Gliostatin; Platelet-derived endothelial cell growth factor; PD-ECGF; TdRPase; EC 2.4.2.4 from Homo sapiens (Human)
P19971 thymidine phosphorylase (EC 2.4.2.4) from Homo sapiens
P19971 thymidine phosphorylase monomer (EC 2.4.2.3; EC 2.4.2.2) from Homo sapiens
PFams: Glycos_trans_3N, Glycos_transf_3, PYNP_C
482 amino acids: PaperBLAST, CDD, Compare to cluster

b4382 thymidine phosphorylase (EC 2.4.2.2; EC 2.4.2.4; EC 2.4.2.3) from Escherichia coli K-12 substr. MG1655
P07650 thymidine phosphorylase (EC 2.4.2.4) from Escherichia coli
P07650 thymidine phosphorylase (EC 2.4.2.2; EC 2.4.2.3) from Escherichia coli (strain K12)
GB|AAC77335.1 thymidine phosphorylase; EC 2.4.2.4 from Escherichia coli K12
PFams: Glycos_trans_3N, Glycos_transf_3, PYNP_C
440 amino acids: PaperBLAST, CDD, Compare to cluster

P75052 thymidine phosphorylase (EC 2.4.2.4) from Mycoplasma pneumoniae
PFams: Glycos_trans_3N, Glycos_transf_3, PYNP_C
421 amino acids: PaperBLAST, CDD, Compare to cluster

AMPPA_THEKO / Q5JCX3 AMP phosphorylase; AMPpase; Nucleoside monophosphate phosphorylase; NMP phosphorylase; EC 2.4.2.57 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
Q5JCX3 AMP phosphorylase (EC 2.4.2.57) from Thermococcus kodakarensis
Q5JCX3 AMP phosphorylase (EC 2.4.2.57) (from HMM only) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
PFams: Glycos_trans_3N, Glycos_transf_3, PYNP_C
503 amino acids: PaperBLAST, CDD, Compare to cluster

Q5SHF9 pyrimidine-nucleoside phosphorylase (EC 2.4.2.2) from Thermus thermophilus
PFams: Glycos_trans_3N, Glycos_transf_3, PYNP_C
423 amino acids: PaperBLAST, CDD, Compare to cluster

Q7CP66 thymidine phosphorylase (EC 2.4.2.4) from Salmonella enterica subsp. enterica serovar Typhimurium
PFams: Glycos_trans_3N, Glycos_transf_3, PYNP_C
440 amino acids: PaperBLAST, CDD, Compare to cluster

Q99N42 thymidine phosphorylase (EC 2.4.2.4) from Mus musculus
PFams: Glycos_trans_3N, Glycos_transf_3, PYNP_C
471 amino acids: PaperBLAST, CDD, Compare to cluster

PDP_BACSU / P39142 Pyrimidine-nucleoside phosphorylase; PYNP; Py-NPase; EC 2.4.2.2 from Bacillus subtilis (strain 168)
GB|CAB15976.2 pyrimidine-nucleoside phosphorylase; EC 2.4.2.2 from Bacillus subtilis
PFams: Glycos_trans_3N, Glycos_transf_3, PYNP_C
433 amino acids: PaperBLAST, CDD, Compare to cluster

PDP_GEOSE / P77836 Pyrimidine-nucleoside phosphorylase; PYNP; Py-NPase; EC 2.4.2.2 from Geobacillus stearothermophilus (Bacillus stearothermophilus)
P77836 pyrimidine-nucleoside phosphorylase monomer (EC 2.4.2.3; EC 2.4.2.2) from Geobacillus stearothermophilus
GB|BAA13512.1 pyrimidine-nucleoside phosphorylase; EC 2.4.2.2 from Geobacillus stearothermophilus
PFams: Glycos_trans_3N, Glycos_transf_3, PYNP_C
433 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 253-277 amino acids (not heteromeric)

Q5XA29 pyrimidine-nucleoside phosphorylase (EC 2.4.2.2) from Streptococcus pyogenes
PFams: PNP_UDP_1
259 amino acids: PaperBLAST, CDD, Compare to cluster

b3831 uridine phosphorylase (EC 2.4.2.2; EC 2.4.2.3) from Escherichia coli K-12 substr. MG1655
P12758 uridine phosphorylase (EC 2.4.2.2) from Escherichia coli (strain K12)
CH_003939 uridine phosphorylase; EC 2.4.2.3 from Escherichia coli K12
PFams: PNP_UDP_1
253 amino acids: PaperBLAST, CDD, Compare to cluster

Q5JJC1 uridine phosphorylase (EC 2.4.2.2) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
PFams: PNP_UDP_1
277 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 295-310 amino acids (not heteromeric)

UPP1_HUMAN / Q16831 Uridine phosphorylase 1; UPase 1; UrdPase 1; EC 2.4.2.3 from Homo sapiens (Human)
Q16831 uridine phosphorylase (EC 2.4.2.3) from Homo sapiens
Q16831 uridine phosphorylase 1 (EC 2.4.2.3; EC 2.4.2.2) from Homo sapiens
PFams: PNP_UDP_1
310 amino acids: PaperBLAST, CDD, Compare to cluster

UTPP_CAEEL / Q23588 Uridine and thymidine phosphorylase; Pyrimidine-nucleoside phosphorylase; EC 2.4.2.2 from Caenorhabditis elegans
PFams: PNP_UDP_1
295 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/1 heteromeric)

b0391 nucleoside phosphorylase PpnP (EC 2.4.2.15; EC 2.4.2.1; EC 2.4.2.2; EC 2.4.2.4; EC 2.4.2.3) from Escherichia coli K-12 substr. MG1655
PPNP_ECOLI / P0C037 Pyrimidine/purine nucleoside phosphorylase; Adenosine phosphorylase; Cytidine phosphorylase; Guanosine phosphorylase; Inosine phosphorylase; Thymidine phosphorylase; Uridine phosphorylase; Xanthosine phosphorylase; EC 2.4.2.1; EC 2.4.2.2; EC 2.4.2.15; EC 2.4.2.4; EC 2.4.2.3 from Escherichia coli (strain K12)
P0C037 nucleoside phosphorylase PpnP (EC 2.4.2.15; EC 2.4.2.2; EC 2.4.2.1) from Escherichia coli (strain K12)
PFams: Ppnp
94 amino acids: PaperBLAST, CDD