Other Characterized Proteins Similar to deoA

GapMind for catabolism of small carbon sources

Other Characterized Proteins Similar to deoA

Finding the characterized proteins for deoA (thymidine phosphorylase DeoA) in thymidine catabolism

Or see clustering for step deoA

Or see all steps for thymidine catabolism

Or cluster curated proteins matching a keyword

Definition of deoA

Curated proteins or TIGRFams with EC 2.4.2.2
Curated proteins or TIGRFams with EC 2.4.2.4
Ignore hits to P19663 when looking for 'other' hits (Thymidine phosphorylase; TdRPase; EC 2.4.2.4)
Ignore hits to items matching 2.4.2.3 when looking for 'other' hits
Comment: P19663 is ignored because it is a sequence fragment. Many uridine phosphorylases (EC 2.4.2.3) are also deoxyuridine phosphorylases and thymidine phosphyrylases, so hits to these are ignored.

Fetched 15 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 11 other characterized sequences. (Found 26 hits including self hits.)

Removing ignored items reduces this to 1 close sequences.

There are also 1 HMM-only high-coverage hits.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for deoA.)

Q72IR2 purine-nucleoside phosphorylase (EC 2.4.2.1) from Thermus thermophilus
PFams: PNP_UDP_1
235 amino acids: PaperBLAST, CDD, BRENDA::Q72IR2
40% identical to

Q5JJC1 uridine phosphorylase (EC 2.4.2.2) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
PFams: PNP_UDP_1
277 amino acids: PaperBLAST, CDD

HMM-only sequences

(Since these sequences' annotations are outside the definition for deoA, HMM hits that are over 40% similar to these sequences will be scored as moderate confidence.)

Q5JCX3 AMP phosphorylase (EC 2.4.2.57) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
AMPPA_THEKO / Q5JCX3 AMP phosphorylase; AMPpase; Nucleoside monophosphate phosphorylase; NMP phosphorylase; EC 2.4.2.57 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
Q5JCX3 AMP phosphorylase (EC 2.4.2.57) from Thermococcus kodakarensis
PFams: Glycos_trans_3N, Glycos_transf_3, PYNP_C
503 amino acids: PaperBLAST, CDD

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for deoA.)

BWI76_RS01295 Uridine phosphorylase (EC 2.4.2.3) from Klebsiella michiganensis M5al
PFams: PNP_UDP_1
253 amino acids: PaperBLAST, CDD, reanno::Koxy:BWI76_RS01295
97% identical to

b3831 uridine phosphorylase (EC 2.4.2.2; EC 2.4.2.3) from Escherichia coli K-12 substr. MG1655
P12758 uridine phosphorylase (EC 2.4.2.2) from Escherichia coli (strain K12)
CH_003939 uridine phosphorylase; EC 2.4.2.3 from Escherichia coli K12
PFams: PNP_UDP_1
253 amino acids: PaperBLAST, CDD

P0A1F6 uridine phosphorylase (EC 2.4.2.3) from Salmonella enterica subsp. enterica serovar Typhimurium
PFams: PNP_UDP_1
253 amino acids: PaperBLAST, CDD, BRENDA::P0A1F6
97% identical to

Q499V1 uridine phosphorylase (EC 2.4.2.3) from Rattus norvegicus
PFams: PNP_UDP_1
312 amino acids: PaperBLAST, CDD, BRENDA::Q499V1
80% identical to

Q16831 uridine phosphorylase 1 (EC 2.4.2.3; EC 2.4.2.2) from Homo sapiens
UPP1_HUMAN / Q16831 Uridine phosphorylase 1; UPase 1; UrdPase 1; EC 2.4.2.3 from Homo sapiens (Human)
Q16831 uridine phosphorylase (EC 2.4.2.3) from Homo sapiens
PFams: PNP_UDP_1
310 amino acids: PaperBLAST, CDD

UPP1_MOUSE / P52624 Uridine phosphorylase 1; UPase 1; UrdPase 1; EC 2.4.2.3 from Mus musculus (Mouse)
PFams: PNP_UDP_1
311 amino acids: PaperBLAST, CDD, SwissProt::P52624
79% identical to

Sama_0412 Uridine phosphorylase (EC 2.4.2.3) from Shewanella amazonensis SB2B
PFams: PNP_UDP_1
252 amino acids: PaperBLAST, CDD, reanno::SB2B:6936223
79% identical to

Shewana3_3680 Uridine phosphorylase (EC 2.4.2.3) from Shewanella sp. ANA-3
PFams: PNP_UDP_1
252 amino acids: PaperBLAST, CDD, reanno::ANA3:7026537
76% identical to

Q9K4U1 uridine phosphorylase (EC 2.4.2.3) from Vibrio cholerae
PFams: PNP_UDP_1
253 amino acids: PaperBLAST, CDD, BRENDA::Q9K4U1
75% identical to

SO4133 Uridine phosphorylase (EC 2.4.2.3) from Shewanella oneidensis MR-1
C7EWM3 uridine phosphorylase (EC 2.4.2.3) from Shewanella oneidensis
PFams: PNP_UDP_1
252 amino acids: PaperBLAST, CDD, BRENDA::C7EWM3
75% identical to

UPP2_HUMAN / O95045 Uridine phosphorylase 2; UPase 2; UrdPase 2; EC 2.4.2.3 from Homo sapiens (Human)
O95045 uridine phosphorylase (EC 2.4.2.3) from Homo sapiens
PFams: PNP_UDP_1
317 amino acids: PaperBLAST, CDD, SwissProt::O95045
65% identical to

Q9YA34 uridine phosphorylase (EC 2.4.2.3) from Aeropyrum pernix
PFams: PNP_UDP_1
282 amino acids: PaperBLAST, CDD, BRENDA::Q9YA34
60% identical to

Q5JJC1 uridine phosphorylase (EC 2.4.2.2) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
PFams: PNP_UDP_1
277 amino acids: PaperBLAST, CDD